cysteamine

CAS 60-23-1C2H7NSMW 77.15

cysteamine（CAS 60-23-1）：分子式 C2H7NS、分子量 77.15；类别有机化学品。

规格参数

CAS号60-23-1

分子式C2H7NS

分子量77.15

熔点67-71

沸点133.6±23.0

LogP0.1

应用领域Uses: Therap Cat: Antidote to acetaminophen、SRP: former、Experimentally as a radioprotective agent and to produce acute and chronic duodenal ulcers in rats.、Use (kg、approx.) in Germany (2009): >50、Consumption (g per capita、approx.) in Germany (2009): 0.000611、Calculated removal (%): 92.1、Formulations、Preparations: U.S.- 50 mg (Rx) Cystagon. 150 mg (Rx) Cystagon.、General Manufacturing Information: While data specific to cysteamine were not available(SRC、2005)、the literature suggests that some pharmaceutically active compounds originating from human and veterinary therapy are not eliminated completely in municipal sewage treatment plants and are therefore discharged into receiving waters(1). Wastewater treatment processes often were not designed to remove them from the effluent(2). Selected organic waste compounds may be degrading to new and more persistent compounds that may be released instead of or in addition to the parent compound(2). Studies have indicated that several polar pharmaceutically active compounds can leach through subsoils into aquifers(1).

类别Organic Chemicals

用途与场景

登记用途：Uses: Therap Cat: Antidote to acetaminophen、SRP: former、Experimentally as a radioprotective agent and to produce acute and chronic duodenal ulcers in rats.、Use (kg、approx.) in Germany (2009): >50、Consumption (g per capita、approx.) in Germany (2009): 0.000611、Calculated removal (%): 92.1、Formulations、Preparations: U.S.- 50 mg (Rx) Cystagon. 150 mg (Rx) Cystagon.、General Manufacturing Information: While data specific to cysteamine were not available(SRC、2005)、the literature suggests that some pharmaceutically active compounds originating from human and veterinary therapy are not eliminated completely in municipal sewage treatment plants and are therefore discharged into receiving waters(1). Wastewater treatment processes often were not designed to remove them from the effluent(2). Selected organic waste compounds may be degrading to new and more persistent compounds that may be released instead of or in addition to the parent compound(2). Studies have indicated that several polar pharmaceutically active compounds can leach through subsoils into aquifers(1).。

采购档案

这个产品是什么

cysteamine 是一种以碳骨架为基础的有机化合物，登记 CAS 号为 60-23-1，分子式 C2H7NS（分子量 77.15），归属于有机化学品大类化工原料。

识别信息

登记 CAS 号：60-23-1

其分子式 C2H7NS 由 2 个碳、7 个氢、1 个氮、1 个硫组成。

别名/同义词：cysteamine

所属分类：有机化学品

常见问题

cysteamine 的 CAS 号是多少？

cysteamine 的 CAS 登记号为 60-23-1。

cysteamine 的分子式与分子量是多少？

分子式 C2H7NS，分子量 77.15。

cysteamine 还有哪些别名？

别名/同义词：cysteamine。

cysteamine 的登记用途是什么？

登记用途：Uses: Therap Cat: Antidote to acetaminophen、SRP: former、Experimentally as a radioprotective agent and to produce acute and chronic duodenal ulcers in rats.、Use (kg、approx.) in Germany (2009): >50、Consumption (g per capita、approx.) in Germany (2009): 0.000611、Calculated removal (%): 92.1、Formulations、Preparations: U.S.- 50 mg (Rx) Cystagon. 150 mg (Rx) Cystagon.、General Manufacturing Information: While data specific to cysteamine were not available(SRC、2005)、the literature suggests that some pharmaceutically active compounds originating from human and veterinary therapy are not eliminated completely in municipal sewage treatment plants and are therefore discharged into receiving waters(1). Wastewater treatment processes often were not designed to remove them from the effluent(2). Selected organic waste compounds may be degrading to new and more persistent compounds that may be released instead of or in addition to the parent compound(2). Studies have indicated that several polar pharmaceutically active compounds can leach through subsoils into aquifers(1).。

cysteamine 属于哪个分类？

所属分类：Organic Chemicals。

PubChem 公开数据

cysteamine（CAS 60-23-1）的公开数据库记录，列此仅供独立核对。

危险化学品分类与危害说明

Reported hazard statements	H302 (100%), H315 (100%), H319 (100%), H335 (97.6%), H317, H318, H402, H412

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

物理形态与操作说明

Solid
Crystals by sublimation in vacuo
Crystals from alcohol
Disagreeable odor
Decomposes
Freely soluble in water.

公开数据库收录的理化数据

沸点	133.6±23.0
熔点	67-71
熔点	97-98.5 °C
熔点	98 °C
LogP	0.1
Dissociation Constants	10.4

这个物质在各数据库里的编号

CAS Registry Number	60-23-1
PubChem CID	6058
分子式	C2H7NS
IUPAC 名称	2-aminoethanethiol
UNII（FDA）	5UX2SD1KE2

数据库记载的用途

Therap Cat: Antidote to acetaminophen /SRP: former/
Experimentally as a radioprotective agent and to produce acute and chronic duodenal ulcers in rats.
Use (kg; approx.) in Germany (2009): >50
Consumption (g per capita; approx.) in Germany (2009): 0.000611
The bitartrate salt of cysteamine is used for the oral treatment of nephropathic cystinosis and cystinuria in adults and in children aged ≥6 years. The hydrochloride salt, formulated as ophthalmic drops, is indicated for the treatment of corneal cystine crystal accumulation in patients with cystinosis. Approved by the EMA for the treatment of corneal cystine crystal accumulation in adults and in children aged ≥6 months with cystinosis
Cysteamine is a simple aminothiol molecule that is used to treat nephropathic cystinosis, due to its ability to decrease the markedly elevated and toxic levels of intracellular cystine that occur in this disease and cause its major complications. Cysteamine has been associated with serum enzyme elevations when given intravenously in high doses, but it has not been shown to cause clinically apparent acute liver injury.

它在各数据库里的别名

CYSTEAMINE; 2-Aminoethanethiol; 60-23-1; Mercaptamine; Thioethanolamine; 2-Mercaptoethylamine; Mercamine; beta-Mercaptoethylamine; Decarboxycysteine; Cysteinamine; 2-Amino-1-ethanethiol; beta-Aminoethanethiol; Ethanethiol, 2-amino-; Mercaptoethylamine; 2-Mercaptoethanamine; beta-Aminoethylthiol

计算机算出的分子描述符

分子量	77.15
XLogP3	-0.4
氢键供体数	2
氢键受体数	2
可旋转键数	1
精确质量	77.02992040
单同位素质量	77.02992040
拓扑极性表面积	27
重原子数	4
形式电荷	0

数据库摘要

cysteamine · CAS 60-23-1 · C2H7NS. UNII 5UX2SD1KE2. 沸点: 133.6±23.0; 熔点: 67-71; 熔点: 97-98.5 °C.

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。