Carbamic acid,[(1S)-1-(2S)-oxiranyl-2-phenylethyl]-, 1,1-dimethylethyl ester, hydrochloride(9CI)

Public-database records for Carbamic acid,[(1S)-1-(2S)-oxiranyl-2-phenylethyl]-, 1,1-dimethylethyl ester, hydrochloride(9CI) (CAS 463-77-4), reproduced here for independent cross-checking.

Physical description and handling notes

• Solid

How this substance is indexed

Documented uses

• This is an endogenously produced metabolite found in the human body. It is used in metabolic reactions, catabolic reactions or waste generation.
• Paraoxonase (PON1) is a key enzyme in the metabolism of organophosphates. PON1 can inactivate some organophosphates through hydrolysis. PON1 hydrolyzes the active metabolites in several organophosphates insecticides as well as, nerve agents such as soman, sarin, and VX. The presence of PON1 polymorphisms causes there to be different enzyme levels and catalytic efficiency of this esterase, which in turn suggests that different individuals may be more susceptible to the toxic effect of OP exposure.

Names this substance appears under

CARBAMIC ACID; Aminoformic acid; 463-77-4; O0UC6XOS4H; DTXSID5048009; CHEBI:28616; azaniumylformate; hydron;carbamate; RefChem:123374; carbamic acid, calcium salt; carbamic acid, potassium salt; DTXCID5027986; imidocarbonic acid; aminocarboxylic acid; SCHEMBL2; Aminoameisensaeure

Computed molecular descriptors

Database abstract

Carbamic acid,[(1,2,3,4-tetrahydro-3-isoquinolinyl)methyl]-, 1,1-dimethylethyl ester (9CI) · CAS 463-77-4 · CH3NO2. UNII O0UC6XOS4H.

Source: PubChem / Wikidata; the batch COA governs where values differ.