C12 Alcohol (CAS 112-53-8) — formula C12H26O, molecular weight 186.33.
Documented applications: Uses: Used to manufacture sulfuric acid esters (wetting agents) and in synthetic detergents, lube additives, pharmaceuticals, rubber, textiles, and perfumes, Also used as a flavoring agent and as a foam stabilizer for alcohol sulfate surfactants, [HSDB] Used to make surfactants for detergents, cleaning products, shampoos, cosmetics, lubricants, wetting agents, emulsifiers, dispersing agents, and antioxidants, Also used to make biocides and disinfectants, 1-Dodecanol is used in foam control, aluminum rolling, metalworking, and in the rubber, and perfume industries, Also used as a froth flotation agent and a flavoring ingredient in non-alcoholic beverages, ice cream, candy, baked goods, chewing gum, and syrups, [CHEMINFO] Used as Lepidoptera pheromone in apple and pear orchards, [EPA], Aluminum Producing [Category: Industry], Metal Machining [Category: Heat or Machine], Textiles (Fiber & Fabric Manufacturing) [Category: Industry], Used to make detergents, sulfonic acid esters (wetting agents), thiodipropionate, lauryl chloride, specialty ethoxylates, sulfate defoamers, rubbers, perfumes, and foaming agents, [HSDB], For 1-dodecanol (USEPA, OPP Pesticide Code: 001509 ) ACTIVE products with label matches., SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses., Manufacture of sulfuric acid esters which are used as wetting agents., Synthetic detergents, flavoring agent., Principally as chemical intermediate for salts of n-dodecyl sulfate, foam stabilizer for alcohol sulfate surfactants, chemical intermediate for ethoxylated 1-dodecanol, alkyl glyceryl ethers and tri-n-dodecyl trithiophosphate, n-dodecyl derivatives such as lactate, thioglycholate, mercaptopropionate, methacrylate and chloride, n-dodecyl sulfosuccinate salts, n-dodecyloxypropylamine and di-n-dodecyl 3, 3'-thiodipropionate, di-n-dodecyl phosphate and di-n-dodecyl hydrogen phosphate, For more Uses (Complete) data for 1-DODECANOL (8 total), please visit the HSDB record page., LAURYL ALCOHOL IS USED IN MFR OF DETERGENTS, MANUFACTURE OF SULFONIC ACID ESTERS WHICH ARE USED AS WETTING AGENTS, INTERMEDIATE FOR PRODUCTION OF THIODIPROPIONATE, LAURYL CHLORIDE, SPECIALTY ETHOXYLATES AND SULFATE DEFOAMERS, LUBE ADDITIVES, PHARMACEUTICALS, RUBBERS, TEXTILES, PERFUMES, FOAMING AGENTS, Use Classification: EPA Safer Chemical Functional Use Classes -> Solvents, Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern, Fragrance Ingredients, Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes, Flavoring Agents -> JECFA Flavorings Index, Cosmetics -> Viscosity controlling, Emollient, Emulsion stabilizing, Emulsifying, Industry Uses: Emulsifier, Not Known or Reasonably Ascertainable, Cleaning agent, Intermediate, Lubricating agent, Solvent, Solubility enhancer, Surfactant (surface active agent), Consumer Uses: Lubricating agent, Emulsifier, Household Products: Information on 50 consumer products that contain Lauryl alcohol in the following categories is provided:, • Auto Products, • Commercial, Institutional, • Inside the Home, • Personal Care, Methods of Manufacturing: Addition of ethylene to triethylaluminum followed by oxidation of the trialkylaluminum growth product, hydrolysis, and fractional distillation, catalytic hydrogenation of methyl laurate., Prepared by the reduction of esters of lauric acid with sodium and absolute alcohol ... or by high pressure hydrogenation of the esters using copper chromite catalyst., Reduction of coconut-oil fatty acids., In former times prepared solely from natural products...now also mfg from ethylene by the Ziegler process and by the Shell version of the oxo process., C12 to C18 alcohols, LAURYL ALCOHOL WAS PREVIOUSLY PREPARED COMMERCIALLY BY REDUCTION OF ETHYL LAURATE (FROM COCONUT OIL) WITH SODIUM & ABSOLUTE ALCOHOL, BUT PRESENTLY IS MFR BY CATALYTIC HYDROGENATION OF COCONUT OIL FATTY ACIDS OR THEIR ESTERS UNDER HIGH PRESSURE., PREPARED BY THE REDUCTION OF ESTERS OF LAURIC ACID WITH SODIUM AND ABSOLUTE ALCOHOL OR BY HIGH PRESSURE HYDROGENATION OF THE ESTERS USING COPPER CHROMITE CATALYSTS, Formulations, Preparations: Grades: Technical, Food Chemical Codex, Royaltac-M (Macdermid Agricultural Solutions, Inc.): Active ingredient: lauryl alcohol 0.3%, 1-octanol 36.2%, 1-decanol 48.2%., Off-Shoot-T (Macdermid Agricultural Solutions, C8-C10 Fatty Alcohol Technical (Macdermid Agricultural Solutions, 1-octanol 42.6%, 1-decanol 56.7%., For more Formulations, Preparations (Complete) data for 1-DODECANOL (17 total), TECHNICAL & F.C.C, Consumption Patterns: Use as a chemical intermediate for n-dodecyl sulfate salts is believed to consume the largest quantity of 1-dodecanol, production of ethoxylated 1-dodecanol is probably the next largest market (1976), In the U.S.A. approximately 20, 000 lbs, year are used in fragrances, and some typical concentrations reported in personal care products include soaps (0.01 - 0.09%), detergents (0.002 - 0.018%), lotions and creams (0.005 - 0.02%) and perfumes (0.09 - 0.25%)., U.S. Production: 2023: 50, 000, 000 - <100, 000 lb, 2022: 100, 000 - <250, 2021: 100, 2020: 70, 000 - <85, (1972) 2.2X10+10 G (INCL C10+ LINEAR ALCOHOLS), (1975) 1.01X10+11 G (INCL HIGHER ALCOHOLS), (1986) >10 million-50 million pounds, (1990) >50 million-100 million pounds, For more U.S. Production (Complete) data for.
C12 Alcohol is a chemical compound with CAS registry number 112-53-8 and molecular formula C12H26O (molecular weight 186.33).
CAS number: 112-53-8
Its molecular formula C12H26O comprises 12 C, 26 H, 1 O atoms.
Also known as: C12 Alcohol · Lauryl alcohol · 1-DODECANOL
The CAS registry number of C12 Alcohol is 112-53-8.
Molecular formula C12H26O, molecular weight 186.33.
It is also registered under: C12 Alcohol, Lauryl alcohol, 1-DODECANOL.
Recorded applications: Uses: Used to manufacture sulfuric acid esters (wetting agents) and in synthetic detergents, lube additives, pharmaceuticals, rubber, textiles, and perfumes, Also used as a flavoring agent and as a foam stabilizer for alcohol sulfate surfactants, [HSDB] Used to make surfactants for detergents, cleaning products, shampoos, cosmetics, lubricants, wetting agents, emulsifiers, dispersing agents, and antioxidants, Also used to make biocides and disinfectants, 1-Dodecanol is used in foam control, aluminum rolling, metalworking, and in the rubber, and perfume industries, Also used as a froth flotation agent and a flavoring ingredient in non-alcoholic beverages, ice cream, candy, baked goods, chewing gum, and syrups, [CHEMINFO] Used as Lepidoptera pheromone in apple and pear orchards, [EPA], Aluminum Producing [Category: Industry], Metal Machining [Category: Heat or Machine], Textiles (Fiber & Fabric Manufacturing) [Category: Industry], Used to make detergents, sulfonic acid esters (wetting agents), thiodipropionate, lauryl chloride, specialty ethoxylates, sulfate defoamers, rubbers, perfumes, and foaming agents, [HSDB], For 1-dodecanol (USEPA, OPP Pesticide Code: 001509 ) ACTIVE products with label matches., SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses., Manufacture of sulfuric acid esters which are used as wetting agents., Synthetic detergents, flavoring agent., Principally as chemical intermediate for salts of n-dodecyl sulfate, foam stabilizer for alcohol sulfate surfactants, chemical intermediate for ethoxylated 1-dodecanol, alkyl glyceryl ethers and tri-n-dodecyl trithiophosphate, n-dodecyl derivatives such as lactate, thioglycholate, mercaptopropionate, methacrylate and chloride, n-dodecyl sulfosuccinate salts, n-dodecyloxypropylamine and di-n-dodecyl 3, 3'-thiodipropionate, di-n-dodecyl phosphate and di-n-dodecyl hydrogen phosphate, For more Uses (Complete) data for 1-DODECANOL (8 total), please visit the HSDB record page., LAURYL ALCOHOL IS USED IN MFR OF DETERGENTS, MANUFACTURE OF SULFONIC ACID ESTERS WHICH ARE USED AS WETTING AGENTS, INTERMEDIATE FOR PRODUCTION OF THIODIPROPIONATE, LAURYL CHLORIDE, SPECIALTY ETHOXYLATES AND SULFATE DEFOAMERS, LUBE ADDITIVES, PHARMACEUTICALS, RUBBERS, TEXTILES, PERFUMES, FOAMING AGENTS, Use Classification: EPA Safer Chemical Functional Use Classes -> Solvents, Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern, Fragrance Ingredients, Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes, Flavoring Agents -> JECFA Flavorings Index, Cosmetics -> Viscosity controlling, Emollient, Emulsion stabilizing, Emulsifying, Industry Uses: Emulsifier, Not Known or Reasonably Ascertainable, Cleaning agent, Intermediate, Lubricating agent, Solvent, Solubility enhancer, Surfactant (surface active agent), Consumer Uses: Lubricating agent, Emulsifier, Household Products: Information on 50 consumer products that contain Lauryl alcohol in the following categories is provided:, • Auto Products, • Commercial, Institutional, • Inside the Home, • Personal Care, Methods of Manufacturing: Addition of ethylene to triethylaluminum followed by oxidation of the trialkylaluminum growth product, hydrolysis, and fractional distillation, catalytic hydrogenation of methyl laurate., Prepared by the reduction of esters of lauric acid with sodium and absolute alcohol ... or by high pressure hydrogenation of the esters using copper chromite catalyst., Reduction of coconut-oil fatty acids., In former times prepared solely from natural products...now also mfg from ethylene by the Ziegler process and by the Shell version of the oxo process., C12 to C18 alcohols, LAURYL ALCOHOL WAS PREVIOUSLY PREPARED COMMERCIALLY BY REDUCTION OF ETHYL LAURATE (FROM COCONUT OIL) WITH SODIUM & ABSOLUTE ALCOHOL, BUT PRESENTLY IS MFR BY CATALYTIC HYDROGENATION OF COCONUT OIL FATTY ACIDS OR THEIR ESTERS UNDER HIGH PRESSURE., PREPARED BY THE REDUCTION OF ESTERS OF LAURIC ACID WITH SODIUM AND ABSOLUTE ALCOHOL OR BY HIGH PRESSURE HYDROGENATION OF THE ESTERS USING COPPER CHROMITE CATALYSTS, Formulations, Preparations: Grades: Technical, Food Chemical Codex, Royaltac-M (Macdermid Agricultural Solutions, Inc.): Active ingredient: lauryl alcohol 0.3%, 1-octanol 36.2%, 1-decanol 48.2%., Off-Shoot-T (Macdermid Agricultural Solutions, C8-C10 Fatty Alcohol Technical (Macdermid Agricultural Solutions, 1-octanol 42.6%, 1-decanol 56.7%., For more Formulations, Preparations (Complete) data for 1-DODECANOL (17 total), TECHNICAL & F.C.C, Consumption Patterns: Use as a chemical intermediate for n-dodecyl sulfate salts is believed to consume the largest quantity of 1-dodecanol, production of ethoxylated 1-dodecanol is probably the next largest market (1976), In the U.S.A. approximately 20, 000 lbs, year are used in fragrances, and some typical concentrations reported in personal care products include soaps (0.01 - 0.09%), detergents (0.002 - 0.018%), lotions and creams (0.005 - 0.02%) and perfumes (0.09 - 0.25%)., U.S. Production: 2023: 50, 000, 000 - <100, 000 lb, 2022: 100, 000 - <250, 2021: 100, 2020: 70, 000 - <85, (1972) 2.2X10+10 G (INCL C10+ LINEAR ALCOHOLS), (1975) 1.01X10+11 G (INCL HIGHER ALCOHOLS), (1986) >10 million-50 million pounds, (1990) >50 million-100 million pounds, For more U.S. Production (Complete) data for.
Public-database records for C12 Alcohol (CAS 112-53-8), reproduced here for independent cross-checking.
| GHS notification summary | 2.2% (85 / 3888) |
|---|---|
| Reported hazard statements | H319 (83.8%), H400 (85.7%), H410 (14%), H411 (24.8%), H320, H370, H412, H371 |
This chemical does not meet GHS hazard criteria for 2.2% (85 of 3888) of reports.
H319 (83.8%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
| Regulatory & Food Contact | EU Flavoring substances FDA Substance added to food: FLAVORING AGENT OR ADJUVANT FDA Cumulative Estimated Daily Intake (CEDI): FCS FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS Flavoring Agents FLAVOURING_AGENT: Flavouring Agent |
|---|---|
| GHS notification summary | 2.2% (85 / 3888) |
| 沸点 | 498 °F at 760 mmHg (USCG, 1999) |
|---|---|
| 沸点 | 259 °C at 760 mm Hg |
| 沸点 | 259 °C |
| 沸点 | at 101.3kPa: 250 °C |
| 沸点 | 260 °C @760 [mm Hg] |
| 熔点 | 75 °F (USCG, 1999) |
| 熔点 | 24 °C |
| 闪点 | 260 °F (USCG, 1999) |
| 闪点 | 127 °C |
| 闪点 | 260 °F (127 °C) (Closed cup) |
| CAS Registry Number | 112-53-8 |
|---|---|
| PubChem CID | 8193 |
| 分子式 | C12H26O |
| IUPAC 名称 | dodecan-1-ol |
| UNII(FDA) | 178A96NLP2 |
| FEMA 编号 | 2617 |
| JECFA 编号 | 109 |
1-DODECANOL; Dodecan-1-ol; Dodecyl alcohol; 112-53-8; Lauryl alcohol; n-Dodecyl alcohol; Lauric alcohol; Laurinic alcohol; Undecyl carbinol; Dodecylalcohol; 1-Hydroxydodecane; Pisol; 1-Dodecyl alcohol; n-Dodecan-1-ol; Duodecyl alcohol; Lorol 5
| 分子量 | 186.33 |
|---|---|
| XLogP3 | 5.1 |
| 氢键供体数 | 1 |
| 氢键受体数 | 1 |
| 可旋转键数 | 10 |
| 精确质量 | 186.198365449 |
| 单同位素质量 | 186.198365449 |
| 拓扑极性表面积 | 20.2 |
| 重原子数 | 13 |
| 形式电荷 | 0 |
1-DODECANOL · CAS 112-53-8 · C12H26O. UNII 178A96NLP2. 沸点: 498 °F at 760 mmHg (USCG, 1999); 沸点: 259 °C at 760 mm Hg; 沸点: 259 °C.
Source: PubChem / Wikidata; the batch COA governs where values differ.
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