Bronopol (CAS 52-51-7) — formula C3H6BrNO4, molecular weight 199.99.
Documented applications: Uses: CIR ingredient: 2-Bromo-2-Nitropropane-1, 3-Diol, Bronopol is a preservative and antiseptic used in cosmetics and topical medications. It is used as a preservative in paints, textiles, cooling towers, humidifiers, and hide processing. [Marks, p. 136-7] Used in cleaning agents, paints, cosmetics, glues, paper mills, water systems, metalworking fluids, polishes, and printing inks, [Kanerva, p. 405], Metal Machining [Category: Heat or Machine], Pulp and Paper Processing [Category: Industry], Painting (Pigments, Binders, and Biocides) [Category: Paint], Working with Glues and Adhesives [Category: Other], Using Disinfectants or Biocides [Category: Clean], Leather Tanning and Processing [Category: Industry], Textiles (Printing, Dyeing, or Finishing) [Category: Industry], Dressing Hair [Category: Other], Preparing and mounting animal skins (taxidermy) [Category: Hobbies], For bronopol (USEPA, OPP Pesticide Code: 216400) ACTIVE products with label matches., SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses., For seed treatment on cotton for Xanthomonas campestris (blackarm diseae)., Biocide used in recirculating cooling towers, FDA (1998) approved the use of, bronopol, in adhesives as a component of articles intended for use in packaging, transporting, or holding food ... ., For more Uses (Complete) data for BRONOPOL (7 total), please visit the HSDB record page., Bronopol is used as a preservative in pharmaceuticals, as well as numerous consumer products such as shampoos and cosmetics. It is also used as an antimicrobial in many industrial environments such as paper mills, oil exploration and production facilities, as well as cooling water disinfection plants. (L643), Use Classification: Cosmetics -> Preservative, Industry Uses: Anti-adhesive, cohesive, Preservative, Pigment, Consumer Uses: Anti-adhesive, Household Products: Information on 38 consumer products that contain 2-Bromo-2-nitropropane-1, 3-diol in the following categories is provided:, • Auto Products, • Commercial, Institutional, • Home Maintenance, • Inside the Home, • Personal Care, Methods of Manufacturing: Bronopol is made by the bromination of the sodium salt of 2-nitropropane-1, 3-diol., Formulations, Preparations: Trade name: Onyxide 500, Formulation types registered: pelleted, tableted, crystalline, soluble concentrate, liquid, solid., Tradename: Bronotak, Powder for dry application., For more Formulations, Preparations (Complete) data for BRONOPOL (49 total), U.S. Production: 2023: <50, 000 lb, 2022: <50, 2021: 250, 000 - <400, 2020: 1, 000, 000 - <5, Production volumes for non-confidential chemicals reported under the Inventory Update Rule.[Table#6821], Production volume for non-confidential chemicals reported under the 2006 Inventory Update Rule. Chemical: 1, 3-Propanediol, 2-bromo-2-nitro-. Aggregated National Production Volume: < 500, 000 pounds., General Manufacturing Information: Paint and Coating Manufacturing, Rubber Product Manufacturing, 1, 2-bromo-2-nitro-: ACTIVE, The WHO Recommended Classification of Pesticides by Hazard identifies bronopol (technical grade) as Class II: moderately hazardous, Main Use: bacteriostat (soil)..
Bronopol is a chemical compound with CAS registry number 52-51-7 and molecular formula C3H6BrNO4 (molecular weight 199.99).
CAS number: 52-51-7
Its molecular formula C3H6BrNO4 comprises 3 C, 6 H, 1 Br, 1 N, 4 O atoms.
Also known as: Bronopol · 2-Bromo-2-nitro-1,3-propanediol
The CAS registry number of Bronopol is 52-51-7.
Molecular formula C3H6BrNO4, molecular weight 199.99.
It is also registered under: Bronopol, 2-Bromo-2-nitro-1,3-propanediol.
Recorded applications: Uses: CIR ingredient: 2-Bromo-2-Nitropropane-1, 3-Diol, Bronopol is a preservative and antiseptic used in cosmetics and topical medications. It is used as a preservative in paints, textiles, cooling towers, humidifiers, and hide processing. [Marks, p. 136-7] Used in cleaning agents, paints, cosmetics, glues, paper mills, water systems, metalworking fluids, polishes, and printing inks, [Kanerva, p. 405], Metal Machining [Category: Heat or Machine], Pulp and Paper Processing [Category: Industry], Painting (Pigments, Binders, and Biocides) [Category: Paint], Working with Glues and Adhesives [Category: Other], Using Disinfectants or Biocides [Category: Clean], Leather Tanning and Processing [Category: Industry], Textiles (Printing, Dyeing, or Finishing) [Category: Industry], Dressing Hair [Category: Other], Preparing and mounting animal skins (taxidermy) [Category: Hobbies], For bronopol (USEPA, OPP Pesticide Code: 216400) ACTIVE products with label matches., SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses., For seed treatment on cotton for Xanthomonas campestris (blackarm diseae)., Biocide used in recirculating cooling towers, FDA (1998) approved the use of, bronopol, in adhesives as a component of articles intended for use in packaging, transporting, or holding food ... ., For more Uses (Complete) data for BRONOPOL (7 total), please visit the HSDB record page., Bronopol is used as a preservative in pharmaceuticals, as well as numerous consumer products such as shampoos and cosmetics. It is also used as an antimicrobial in many industrial environments such as paper mills, oil exploration and production facilities, as well as cooling water disinfection plants. (L643), Use Classification: Cosmetics -> Preservative, Industry Uses: Anti-adhesive, cohesive, Preservative, Pigment, Consumer Uses: Anti-adhesive, Household Products: Information on 38 consumer products that contain 2-Bromo-2-nitropropane-1, 3-diol in the following categories is provided:, • Auto Products, • Commercial, Institutional, • Home Maintenance, • Inside the Home, • Personal Care, Methods of Manufacturing: Bronopol is made by the bromination of the sodium salt of 2-nitropropane-1, 3-diol., Formulations, Preparations: Trade name: Onyxide 500, Formulation types registered: pelleted, tableted, crystalline, soluble concentrate, liquid, solid., Tradename: Bronotak, Powder for dry application., For more Formulations, Preparations (Complete) data for BRONOPOL (49 total), U.S. Production: 2023: <50, 000 lb, 2022: <50, 2021: 250, 000 - <400, 2020: 1, 000, 000 - <5, Production volumes for non-confidential chemicals reported under the Inventory Update Rule.[Table#6821], Production volume for non-confidential chemicals reported under the 2006 Inventory Update Rule. Chemical: 1, 3-Propanediol, 2-bromo-2-nitro-. Aggregated National Production Volume: < 500, 000 pounds., General Manufacturing Information: Paint and Coating Manufacturing, Rubber Product Manufacturing, 1, 2-bromo-2-nitro-: ACTIVE, The WHO Recommended Classification of Pesticides by Hazard identifies bronopol (technical grade) as Class II: moderately hazardous, Main Use: bacteriostat (soil)..
Public-database records for Bronopol (CAS 52-51-7), reproduced here for independent cross-checking.
| GHS notification summary | 0.1% (1 / 2149) |
|---|---|
| Reported hazard statements | H302, H312, H315, H318, H335, H400, H301 (14.4%), H331 (10%) |
H302: Harmful if swallowed [Warning Acute toxicity, oral]
H312: Harmful in contact with skin [Warning Acute toxicity, dermal]
| Regulatory & Food Contact | FDA Cumulative Estimated Daily Intake (CEDI): FCS FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS FDA Inventory of Effective Food Contact Substance (FCS) Noti: FCS 2-Bromo-2-nitro-1,3-propanediol (CAS Reg. No. 52-51-7) As a preservative for boiler water additive formulations. For use only as a preservative in boiler water additive formulations. The food-contact substance shall be adde |
|---|---|
| GHS notification summary | 0.1% (1 / 2149) |
| 沸点 | 305.1 °F at 760 mmHg (NTP, 1992) |
|---|---|
| 沸点 | 130 |
| 熔点 | 266 to 271 °F (NTP, 1992) |
| 熔点 | 123-130 |
| 熔点 | 131.5 °C |
| 熔点 | 120-122 °C |
| 闪点 | 167 °C |
| 溶解度 | 25-25g/100mL at 22°C |
| 溶解度 | In water, 2.5X10+5 mg/L at 22 °C |
| 蒸气压 | 1.2601e-05 mmHg at 68 °F (NTP, 1992) |
| CAS Registry Number | 52-51-7 |
|---|---|
| PubChem CID | 2450 |
| 分子式 | C3H6BrNO4 |
| IUPAC 名称 | 2-bromo-2-nitropropane-1,3-diol |
| UNII（FDA） | 6PU1E16C9W |
bronopol; 52-51-7; 2-Bromo-2-nitro-1,3-propanediol; 2-Bromo-2-nitropropane-1,3-diol; Bronosol; Bronocot; Bronotak; Bronidiol; Bronopolu; Lexgard bronopol; Onyxide 500; Bronopolum; 1,3-Propanediol, 2-bromo-2-nitro-; 2-Nitro-2-bromo-1,3-propanediol; DTXSID8024652; beta-Bromo-beta-nitrotrimethyleneglycol
| 分子量 | 199.99 |
|---|---|
| XLogP3 | -0.6 |
| 氢键供体数 | 2 |
| 氢键受体数 | 4 |
| 可旋转键数 | 2 |
| 精确质量 | 198.94802 |
| 单同位素质量 | 198.94802 |
| 拓扑极性表面积 | 86.3 |
| 重原子数 | 9 |
| 形式电荷 | 0 |
Bronopol · CAS 52-51-7 · C3H6BrNO4. UNII 6PU1E16C9W. 沸点: 305.1 °F at 760 mmHg (NTP, 1992); 沸点: 130; 熔点: 266 to 271 °F (NTP, 1992).
Source: PubChem / Wikidata; the batch COA governs where values differ.
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