hexyl 2-(1-(diethylaminohydroxyphenyl)methanoyl)benzoate

Public-database records for hexyl 2-(1-(diethylaminohydroxyphenyl)methanoyl)benzoate (CAS 302776-68-7), reproduced here for independent cross-checking.

Safety classification and hazard statements

Regulatory listings

Physical description and handling notes

• 54, Decomposes at 314
• Diethylamino hydroxybenzoyl hexyl benzoate is an organic UV filter that attenuates the exposure of UV radiation on human skin. _In vitro_, topical application of diethylamino hydroxybenzoyl hexyl benzoate exerted an anti-inflammatory effect on inflammation-evoked mouse ears by inhibiting oedema formation.

Reported physical properties

How this substance is indexed

Documented uses

• Information on 1 consumer products that contain Hexyl 2-(1-(diethylaminohydroxyphenyl)methanoyl)benzoate in the following categories is provided:
• Indicated for use as a sunscreen agent.
• Based on the findings of a rat study assessing dermal or percutaneous absorption, only a minor amount of diethylamino hydroxybenzoyl hexyl benzoate will undergo percutaneous absorption and most of the compounds will remain in the upper layers of the stratum corneum. In rat and porcine skin, the percutaneous absorption was 0.10 ± 0.12 μg/cm^2 or 0.04 ± 0.05%.
• In steady-state and transient photolysis experiments _in vitro_, diethylamino hydroxybenzoyl hexyl benzoate may be oxidized by H2O2/UV to form degradation products. Like other UV filters, diethylamino hydroxybenzoyl hexyl benzoate may be subject to photodegradation upon absorption of UV radiation, which results in the compound passing from a ground state to either a singlet or triplet excited state.
• Diethylamino hydroxybenzoyl hexyl benzoate absorbs in the UV-A range with the peak at 354 nm.

Names this substance appears under

302776-68-7; Diethylamino hydroxybenzoyl hexyl benzoate; Hexyl 2-(4-(diethylamino)-2-hydroxybenzoyl)benzoate; Hexyl 2-[4-(Diethylamino)-2-hydroxybenzoyl]benzoate; Benzoic acid, 2-[4-(diethylamino)-2-hydroxybenzoyl]-, hexyl ester; ANQ870JD20; DTXSID60184370; Benzoic acid, 2-(4-(diethylamino)-2-hydroxybenzoyl)-, hexyl ester; RefChem:133468; DTXCID70106861; 443-860-6; 608-453-1; Uvinul A Plus; MFCD11616752; 2-[4-(DIETHYLAMINO)-2-HYDROXYBENZOYL]BENZOIC ACID HEXYL ESTER; C24H31NO4

Computed molecular descriptors

Database abstract

hexyl 2-(1-(diethylaminohydroxyphenyl)methanoyl)benzoate · CAS 302776-68-7 · C24H31NO4. UNII ANQ870JD20. 溶解度: < 0.01 mg/L; LogP: 6.2.

Source: PubChem / Wikidata; the batch COA governs where values differ.