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Finerenone

CAS 1050477-31-0C21H22N4O3MW 378.4

Finerenone(CAS 1050477-31-0):分子式 C21H22N4O3、分子量 378.4。

规格参数

CAS号1050477-31-0
分子式C21H22N4O3
分子量378.4
LogP2.51

采购档案

这个产品是什么

Finerenone 是一种化工化合物,登记 CAS 号为 1050477-31-0,分子式 C21H22N4O3(分子量 378.4)。

识别信息

登记 CAS 号:1050477-31-0

其分子式 C21H22N4O3 由 21 个碳、22 个氢、4 个氮、3 个氧 组成。

别名/同义词:Finerenone

常见问题

Finerenone 的 CAS 号是多少?

Finerenone 的 CAS 登记号为 1050477-31-0。

Finerenone 的分子式与分子量是多少?

分子式 C21H22N4O3,分子量 378.4。

Finerenone 还有哪些别名?

别名/同义词:Finerenone。

PubChem 公开数据

Finerenone(CAS 1050477-31-0)的公开数据库记录,列此仅供独立核对。

危险化学品分类与危害说明

Reported hazard statementsH301 (100%), H360 (66.7%), H362 (33.3%), H373 (33.3%), H410 (66.7%)

H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]

H360 (66.7%): May damage fertility or the unborn child [Danger Reproductive toxicity]

公开数据库收录的理化数据

LogP2.51

这个物质在各数据库里的编号

CAS Registry Number1050477-31-0
PubChem CID60150535
分子式C21H22N4O3
IUPAC 名称(4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide
UNII(FDA)DE2O63YV8R

数据库记载的用途

  • Finerenone is a selective, nonsteroidal mineralocorticoid receptor antagonist that is used in the therapy of chronic renal disease in patients with type 2 diabetes to slow progression of renal dysfunction and reduce the risk of cardiovascular disease morbidity and mortality. Finerenone has not been linked to serum enzyme elevations during therapy or with instances of clinically apparent liver injury.
  • Breast Feeding; Lactation; Mineralocorticoid Receptor Antagonists
  • Avoid grapefruit products. Grapefruit products may increase exposure to finerenone, increasing the risk and severity of adverse effects.
  • Take with or without food. Food does not have a clinically significant effect on area under the curve.
  • Established Pharmacologic Class [EPC] - Nonsteroidal Mineralocorticoid-Receptor Antagonist
  • Mechanisms of Action [MoA] - Mineralocorticoid Receptor Antagonists

它在各数据库里的别名

Finerenone; 1050477-31-0; Kerendia; (4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide; BAY94-8862; BAY 94-8862; finerenona; finerenonum; DE2O63YV8R; BAY-94-8862; (4S)-4-(4-Cyano-2-methoxyphenyl)-5-ethoxy-1,4-dihydro-2,8-dimethyl-1,6-naphthyridine-3-carboxamide; DTXSID10146928; RefChem:57201; DTXCID5069419; 814-499-5; Finerenone (BAY 94-8862)

计算机算出的分子描述符

分子量378.4
XLogP32.4
氢键供体数2
氢键受体数6
可旋转键数5
精确质量378.16919058
单同位素质量378.16919058
拓扑极性表面积110
重原子数28
形式电荷0

数据库摘要

Finerenone · CAS 1050477-31-0 · C21H22N4O3. UNII DE2O63YV8R. LogP: 2.51.

数据来源:PubChem / Wikidata;与随货 COA 不一致时以 COA 为准。

获取 Finerenone 报价

供应商:济南圣和化工有限公司 · 一个工作日内回复。

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