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Amiloride hydrochloride

CAS 17440-83-4C6H8ClN7O.ClHMW 266.09

Amiloride hydrochloride (CAS 17440-83-4) — formula C6H8ClN7O.ClH, molecular weight 266.09.

Specifications

CAS Number17440-83-4
Molecular FormulaC6H8ClN7O.ClH
Molecular Weight266.09
Melting Point560.3 °F (NTP, 1992)

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What this product is

Amiloride hydrochloride is a chemical compound with CAS registry number 17440-83-4 and molecular formula C6H8ClN7O.ClH (molecular weight 266.09).

Identification

CAS number: 17440-83-4

Its molecular formula C6H8ClN7O.ClH comprises 6 C, 9 H, 2 Cl, 7 N, 1 O atoms.

Also known as: Amiloride hydrochloride · Amiloride hydrochloride dihydrate

Frequently Asked Questions

What is the CAS number of Amiloride hydrochloride?

The CAS registry number of Amiloride hydrochloride is 17440-83-4.

What is the molecular formula and molecular weight of Amiloride hydrochloride?

Molecular formula C6H8ClN7O.ClH, molecular weight 266.09.

What other names is Amiloride hydrochloride known by?

It is also registered under: Amiloride hydrochloride, Amiloride hydrochloride dihydrate.

PubChem Public Data

Public-database records for Amiloride hydrochloride (CAS 17440-83-4), reproduced here for independent cross-checking.

Safety classification and hazard statements

Reported hazard statementsH301 (100%), H315 (63.3%), H319 (63.3%), H412 (62.5%)

H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]

H315 (63.3%): Causes skin irritation [Warning Skin corrosion/irritation]

Physical description and handling notes

  • Amiloride hydrochloride appears as crystalline solid or very light yellow powder. (NTP, 1992)
  • less than 1 mg/mL at 67.1 °F (NTP, 1992)
  • 145.7 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

Reported physical properties

熔点560.3 °F (NTP, 1992)

How this substance is indexed

CAS Registry Number17440-83-4
PubChem CID16230
分子式C6H8ClN7O.ClH
IUPAC 名称3,5-diamino-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide;hydrochloride
UNII(FDA)7M458Q65S3

Documented uses

  • Agents that promote the excretion of urine through their effects on kidney function.
  • A subclass of sodium channel blockers that are specific for ACID-SENSING SODIUM CHANNELS.
  • A subclass of sodium channel blockers that are specific for EPITHELIAL SODIUM CHANNELS.

Names this substance appears under

2016-88-8; Amiloride chloride; Amiloride hydrochloride anhydrous; CCRIS 5959; Amiloride Hydrochloride, Anhydrous; 7M458Q65S3; Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-, monohydrochloride; Anhydrous Amiloride Hydrochloride; RefChem:870453; Hydrochloride, Anhydrous Amiloride; 217-958-2; Amiloride HCl anhydrous; Amiloride hydrochloride hydrate; Amiloride (hydrochloride); 3,5-diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide hydrochloride; 3,5-Diamino-N-(aminoiminomethyl)-6-chloropyrazinecarboxamide hydrochloride

Computed molecular descriptors

分子量266.09
氢键供体数5
氢键受体数5
可旋转键数1
精确质量265.0245633
单同位素质量265.0245633
拓扑极性表面积159
重原子数16
形式电荷0
复杂度279

Database abstract

Amiloride hydrochloride · CAS 17440-83-4 · C6H8ClN7O.ClH. UNII 7M458Q65S3. 熔点: 560.3 °F (NTP, 1992).

Source: PubChem / Wikidata; the batch COA governs where values differ.

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