Imiquimod (CAS 99011-02-6) — formula C14H16N4, molecular weight 240.30.
Documented applications: Uses: MEDICATION, Adjuvants, Immunologic, Antineoplastic Agents, Use (kg, approx.) in Germany (2009): >10, Use (kg) in USA (2002): 680, Consumption (g per capita, approx.) in Germany (2009): 0.000122, Consumption (g per capita) in the USA (2002): 0.00241, Calculated removal (%): 31.5, Methods of Manufacturing: Preparation: J. F. Gerster, European Patent Office 145340, idem, United States of America 4689338 (1985, 1987 both to Riker), Formulations, Preparations: For topical use, imiquimod is commercially, available, as a 5% cream. Each gram of the cream contains 50 mg of imiquimod in an off-white, oil-in-water vanishing cream base. Imiquimod topical cream contains methylparaben and propylparaben as preservatives., Topical: Cream 5%, Aldara (Graceway)., Zyclara, Beselna, General Manufacturing Information: Cellulose, hydrogen 1, 2-benzenedicarboxylate, 2-hydroxypropyl methyl ether: ACTIVE.
Imiquimod is a chemical compound with CAS registry number 99011-02-6 and molecular formula C14H16N4 (molecular weight 240.30).
CAS number: 99011-02-6
Its molecular formula C14H16N4 comprises 14 C, 16 H, 4 N atoms.
Also known as: Imiquimod · Hypromellose · Hydroxypropyl Methylcellulose Phthalate
The CAS registry number of Imiquimod is 99011-02-6.
Molecular formula C14H16N4, molecular weight 240.30.
It is also registered under: Imiquimod, Hypromellose, Hydroxypropyl Methylcellulose Phthalate.
Recorded applications: Uses: MEDICATION, Adjuvants, Immunologic, Antineoplastic Agents, Use (kg, approx.) in Germany (2009): >10, Use (kg) in USA (2002): 680, Consumption (g per capita, approx.) in Germany (2009): 0.000122, Consumption (g per capita) in the USA (2002): 0.00241, Calculated removal (%): 31.5, Methods of Manufacturing: Preparation: J. F. Gerster, European Patent Office 145340, idem, United States of America 4689338 (1985, 1987 both to Riker), Formulations, Preparations: For topical use, imiquimod is commercially, available, as a 5% cream. Each gram of the cream contains 50 mg of imiquimod in an off-white, oil-in-water vanishing cream base. Imiquimod topical cream contains methylparaben and propylparaben as preservatives., Topical: Cream 5%, Aldara (Graceway)., Zyclara, Beselna, General Manufacturing Information: Cellulose, hydrogen 1, 2-benzenedicarboxylate, 2-hydroxypropyl methyl ether: ACTIVE.
Public-database records for Imiquimod (CAS 99011-02-6), reproduced here for independent cross-checking.
| GHS notification summary | 2.1% (1 / 47) |
|---|---|
| Reported hazard statements | H300 (83%), H315 (93.6%), H319 (91.5%), H335 (87.2%), H413 (50%) |
This chemical does not meet GHS hazard criteria for 2.1% (1 of 47) of reports.
H300 (83%): Fatal if swallowed [Danger Acute toxicity, oral]
| GHS notification summary | 2.1% (1 / 47) |
|---|
| 熔点 | 292-294 °C |
|---|---|
| 熔点 | 292 - 294 °C |
| 溶解度 | 2.47e-01 g/L |
| LogP | 2.7 |
| LogP | 2.89 |
| CAS Registry Number | 99011-02-6 |
|---|---|
| PubChem CID | 57469 |
| 分子式 | C14H16N4 |
| IUPAC 名称 | 1-(2-methylpropyl)imidazo[4,5-c]quinolin-4-amine |
| UNII（FDA） | P1QW714R7M |
IMIQUIMOD; 99011-02-6; Aldara; 1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine; Zyclara; 1-isobutyl-1H-imidazo[4,5-c]quinolin-4-amine; 4-Amino-1-isobutyl-1H-imidazo[4,5-c]quinoline; R-837; R 837; 4-Amino-1-isobutyl-1H-imidazo(4,5-c)quinoline; S-26308; DTXSID7041047; TMX-101; S 26308; Imiquimodum; S26308
| 分子量 | 240.30 |
|---|---|
| XLogP3 | 2.6 |
| 氢键供体数 | 1 |
| 氢键受体数 | 3 |
| 可旋转键数 | 2 |
| 精确质量 | 240.137496527 |
| 单同位素质量 | 240.137496527 |
| 拓扑极性表面积 | 56.7 |
| 重原子数 | 18 |
| 形式电荷 | 0 |
Imiquimod · CAS 99011-02-6 · C14H16N4. UNII P1QW714R7M. 熔点: 292-294 °C; 熔点: 292 - 294 °C; 溶解度: 2.47e-01 g/L.
Source: PubChem / Wikidata; the batch COA governs where values differ.
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