Acetamide Reagent (CAS 60-35-5) — formula C2H5NO, molecular weight 59.07; category organic chemicals.
Documented applications: Uses: Acetamide is used as a solvent, plasticizer, and a wetting and penetrating agent., Used as a solvent, stabilizer, humectant for paper, hygroscopic agent, wetting agent, penetrating agent, and denaturant of alcohol, Also used in lacquers, explosives, and soldering fluxes, [HSDB] Used as a solvent in the following applications: plasticizers, lacquers, soldering flux, wetting agents, and synthesis of other agents, [ACGIH], Soldering [Category: Heat or Machine], Pulp and Paper Processing [Category: Industry], Painting (Solvents) [Category: Paint], Solvent, molten acetamide is an excellent solvent for many organic and inorganic compounds. Solubilizer, renders sparingly soluble substances more soluble in water by mere addition or by fusion. Plasticizer, stabilizer. Manufacture of methylamine, denaturing alcohol. In organic synthesis., Organic synthesis (reactant, solvent, peroxide stabilizer), general solvent, penetrating agent., It suppresses acid buildup in printing inks, and perfumes. It is a mild moisturizer and is used as a softener for leather, textiles, paper, and certain plastics. ... Acetamide and substituted acetamide-containing thiourea can be used for treatment of herpes viruses. Derivatives can also be used as feeding behavior modifiers., MEDICATION, This is an endogenously produced metabolite found in the human body. It is used in metabolic reactions, catabolic reactions or waste generation., Use Classification: Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes, Methods of Manufacturing: Prepared by fractional distillation of ammonium acetate., Interaction of ethyl acetate and ammonium hydroxide., Acetamide can be produced by several methods. Ammonia reacts vigorously with acetyl halides or acetic anhydride to produce acetamide. Alkyl acetates also react with ammonia to yield acetamide. Dehydration of ammonium acetate is the standard procedure for preparation of acetamide. Finally, acetonitrile is hydrolyzed to yield acetamide in the presence of an acid or base catalyst., Formulations, Preparations: In 1963 ... available in USA as technical grade (99% minimum acetamide and 0.3% maximum free acid) and as chemically pure, odorless grade (99.5-99.9% acetamide and trace of free acid)., Grades: Technical, CP, chemically pure: a grade designation signifying a minimum of impurities, but not 100% purity, (odorless), intermediate, reagent., General Manufacturing Information: Acetamide: ACTIVE.
Acetamide Reagent is a carbon-based organic compound with CAS registry number 60-35-5 and molecular formula C2H5NO (molecular weight 59.07), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 60-35-5
Its molecular formula C2H5NO comprises 2 C, 5 H, 1 N, 1 O atoms.
Also known as: Acetamide Reagent · Acetamide
Category: organic chemicals
The CAS registry number of Acetamide Reagent is 60-35-5.
Molecular formula C2H5NO, molecular weight 59.07.
It is also registered under: Acetamide Reagent, Acetamide.
Recorded applications: Uses: Acetamide is used as a solvent, plasticizer, and a wetting and penetrating agent., Used as a solvent, stabilizer, humectant for paper, hygroscopic agent, wetting agent, penetrating agent, and denaturant of alcohol, Also used in lacquers, explosives, and soldering fluxes, [HSDB] Used as a solvent in the following applications: plasticizers, lacquers, soldering flux, wetting agents, and synthesis of other agents, [ACGIH], Soldering [Category: Heat or Machine], Pulp and Paper Processing [Category: Industry], Painting (Solvents) [Category: Paint], Solvent, molten acetamide is an excellent solvent for many organic and inorganic compounds. Solubilizer, renders sparingly soluble substances more soluble in water by mere addition or by fusion. Plasticizer, stabilizer. Manufacture of methylamine, denaturing alcohol. In organic synthesis., Organic synthesis (reactant, solvent, peroxide stabilizer), general solvent, penetrating agent., It suppresses acid buildup in printing inks, and perfumes. It is a mild moisturizer and is used as a softener for leather, textiles, paper, and certain plastics. ... Acetamide and substituted acetamide-containing thiourea can be used for treatment of herpes viruses. Derivatives can also be used as feeding behavior modifiers., MEDICATION, This is an endogenously produced metabolite found in the human body. It is used in metabolic reactions, catabolic reactions or waste generation., Use Classification: Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes, Methods of Manufacturing: Prepared by fractional distillation of ammonium acetate., Interaction of ethyl acetate and ammonium hydroxide., Acetamide can be produced by several methods. Ammonia reacts vigorously with acetyl halides or acetic anhydride to produce acetamide. Alkyl acetates also react with ammonia to yield acetamide. Dehydration of ammonium acetate is the standard procedure for preparation of acetamide. Finally, acetonitrile is hydrolyzed to yield acetamide in the presence of an acid or base catalyst., Formulations, Preparations: In 1963 ... available in USA as technical grade (99% minimum acetamide and 0.3% maximum free acid) and as chemically pure, odorless grade (99.5-99.9% acetamide and trace of free acid)., Grades: Technical, CP, chemically pure: a grade designation signifying a minimum of impurities, but not 100% purity, (odorless), intermediate, reagent., General Manufacturing Information: Acetamide: ACTIVE.
Category: Organic Chemicals.
Public-database records for Acetamide Reagent (CAS 60-35-5), reproduced here for independent cross-checking.
| Reported hazard statements | H351, H361, H320, H316 |
|---|
H351: Suspected of causing cancer [Warning Carcinogenicity]
P203, P280, P318, P405, and P501 (click each P-code to see the statement)
| Regulatory & Food Contact | FDA Substance added to food: FLAVORING AGENT OR ADJUVANT FLAVOURING_AGENT: Flavouring Agent ACETAMIDE--NLFG TRS 934-JECFA 65/89 FAS 56-JECFA 65 |
|---|
| 沸点 | 430 °F at 760 mmHg (NTP, 1992) |
|---|---|
| 沸点 | 222 |
| 沸点 | 222 °C at 760 mm Hg |
| 沸点 | 221.00 to 222.00 °C. @ 760.00 mm Hg |
| 沸点 | 222 °C |
| 沸点 | 430 °F |
| 沸点 | 221 °C @760 [mm Hg] |
| 熔点 | 180.1 °F (NTP, 1992) |
| 熔点 | 81 |
| 熔点 | 81.16 °C |
| CAS Registry Number | 60-35-5 |
|---|---|
| PubChem CID | 178 |
| 分子式 | C2H5NO |
| IUPAC 名称 | acetamide |
| UNII（FDA） | 8XOE1JSO29 |
| JECFA 编号 | 1592 |
acetamide; 60-35-5; Ethanamide; Acetic acid amide; Methanecarboxamide; Acetimidic acid; Ethanimidic acid; Amid kyseliny octove; NCI-C02108; CH3CONH2; DTXSID7020005; AI3-02060; 8XOE1JSO29; NSC 25945; NSC-25945; DTXCID505
| 分子量 | 59.07 |
|---|---|
| XLogP3 | -0.9 |
| 氢键供体数 | 1 |
| 氢键受体数 | 1 |
| 可旋转键数 | 0 |
| 精确质量 | 59.037113783 |
| 单同位素质量 | 59.037113783 |
| 拓扑极性表面积 | 43.1 |
| 重原子数 | 4 |
| 形式电荷 | 0 |
Acetamide Reagent · CAS 60-35-5 · C2H5NO. UNII 8XOE1JSO29. 沸点: 430 °F at 760 mmHg (NTP, 1992); 沸点: 222; 沸点: 222 °C at 760 mm Hg.
Source: PubChem / Wikidata; the batch COA governs where values differ.
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