Nafamostat Mesylate

Public-database records for Nafamostat Mesylate (CAS 82956-11-4), reproduced here for independent cross-checking.

Safety classification and hazard statements

How this substance is indexed

Documented uses

• Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.
• Agents that prevent BLOOD CLOTTING.
• Compounds which inhibit or antagonize biosynthesis or actions of proteases (ENDOPEPTIDASES).
• Serine proteinase inhibitors which inhibit trypsin. They may be endogenous or exogenous compounds.
• Exogenous or endogenous compounds which inhibit SERINE ENDOPEPTIDASES.
• Compounds that negatively regulate the cascade process of COMPLEMENT ACTIVATION. Uncontrolled complement activation and resulting cell lysis is potentially dangerous for the host.

Names this substance appears under

Nafamostat mesylate; 82956-11-4; nafamostat mesilate; FUT-175; Nafamstat Mesilate; Ronastat; Nafamostat dimethanesulfonate; 1D2T74921W; Benzoic acid, 4-[(aminoiminomethyl)amino]-, 6-(aminoiminomethyl)-2-naphthalenyl ester, dimethanesulfonate; DTXSID7046128; FUT 175; 6-Amidino-2-naphthyl 4-guanidinobenzoate dimethanesulfonate; CKD-314; Benzoic acid, 4-((aminoiminomethyl)amino)-, 6-(aminoiminomethyl)-2-naphthalenyl ester, dimethanesulfonate; RefChem:164397; FUT175

Computed molecular descriptors

Database abstract

Nafamostat Mesylate · CAS 82956-11-4 · C21H25N5O8S2. UNII 1D2T74921W.

Source: PubChem / Wikidata; the batch COA governs where values differ.