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Gluconolactone

CAS 90-80-2C6H10O6MW 178.14

Gluconolactone (CAS 90-80-2) — formula C6H10O6, molecular weight 178.14; category organic chemicals.

Specifications

CAS Number90-80-2
Molecular FormulaC6H10O6
Molecular Weight178.14
Melting Point155 °C /decomposes/
LogP-2
ApplicationsUses: CIR ingredient: Glucarolactone, CIR ingredient: Gluconolactone, Used in cleaning compounds, the dairy and brewery industries, textile printing, and tofu production (coagulant), [Merck Index] Used as a curing or pickling agent, flavoring agent, formulation aid, leavening agent, pH control agent, and sequestrant for foods, [FDA] Permitted for use as an inert ingredient in non-food pesticide products, [EPA] Important intermediate in carbohydrate metabolism in mammals, Used for industrial cleaning, metal surface treatment, textile bleach stabilizing, aluminum processing, and as a chelating agent in cement set retarding, cleaning products, personal care products, pharmaceuticals, and foods, [OECD SIDS: Gluconic acid and its derivatives - 2004], Aluminum Producing [Category: Industry], Acid and Alkali Cleaning of Metals [Category: Clean], Textiles (Fiber & Fabric Manufacturing) [Category: Industry], Cement Producing [Category: Industry], Textiles (Printing, Dyeing, or Finishing) [Category: Industry], Component of many cleaning compounds because of the sequestering ability of the gluconate radical which remains active in alkaline solutions, in the dairy industry to prevent milkstone, in breweries to prevent beerstone, as latent acid catalyst for acid colloid resins, particularly in textile printing, as a coagulant for tofu., Sequestering agent, Food additive, Medication (Vet), Use Classification: EPA Safer Chemical Functional Use Classes -> Preservatives and Antioxidants, Processing Aids and Additives, Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern, Food Additives -> ACID, ACIDITY_REGULATOR, RAISING_AGENT, SEQUESTRANT -> JECFA Functional Classes, Cosmetics -> Skin conditioning, Solvent, Humectant, Industry Uses: Processing aids not otherwise specified, Not Known or Reasonably Ascertainable, Intermediate, Chelating agent, Consumer Uses: Processing aids not otherwise specified, Household Products: Information on 41 consumer products that contain Gluconolactone in the following categories is provided:, • Inside the Home, • Personal Care, • Pet Care, Methods of Manufacturing: By oxidation of glucose with bromine water ... by oxidation of glucose in Acetobacter suboxydans, Glucono-1, 5-lactone crystallizes from a supersaturated aqueous gluconic acid solution between 36 and 57 °C. A two-step continuous crystallization is said to result in increased productivity per unit volume under conditions that are favorable in terms of energy consumption. In the first step, a crystalline suspension (3 to 10 % crystalline material) is produced in a supersaturated gluconic acid solution held at 65 to 75 °C. The second step involves controlled cooling to 40 to 45 °C, followed by a period of crystal maturation at constant temperature. A portion of the resulting crystalline suspension is then recycled to the first step. ... The 1, 5-lactone may also be obtained from an aqueous gluconic acid solution by dehydration involving azeotropic distillation with alcohols, followed by crystallization from the alcohol-containing residue. Crystallization above 70 °C leads to the 1, 4-lactone., U.S. Production: 2023: 3, 750, 236 lb, 2022: 4, 124, 048 lb, 2021: 4, 439, 127 lb, 2020: 3, 657, 983 lb, This chemical is listed as a High Production Volume (HPV) (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and, or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B, 51FR21438)., (1986) >1 million - 10 million pounds, (1990) >1 million - 10 million pounds, (1994) >1 million - 10 million pounds, (2002) 10 thousand - 500 thousand pounds, General Manufacturing Information: Non-metallic Mineral Product Manufacturing (includes clay, glass, cement, concrete, lime, gypsum, and other non-metallic mineral product manufacturing), All Other Chemical Product and Preparation Manufacturing, All Other Basic Organic Chemical Manufacturing, D-Gluconic acid, .delta.-lactone: ACTIVE, Structure: J Stanek et al, The Monosaccharides (Academic Press, NY 1963) p 271., Glucono-delta-lactone is direct food additive limited by meat inspection div to use at, 8 oz, 100 lb of cured, comminuted meat or meat product to speed up color-fixing process & to reduce time required for smoking, must be listed in product ingredient statement.
CategoryOrganic Chemicals|Stabilizers & Coagulants

Where it is used

Documented applications: Uses: CIR ingredient: Glucarolactone, CIR ingredient: Gluconolactone, Used in cleaning compounds, the dairy and brewery industries, textile printing, and tofu production (coagulant), [Merck Index] Used as a curing or pickling agent, flavoring agent, formulation aid, leavening agent, pH control agent, and sequestrant for foods, [FDA] Permitted for use as an inert ingredient in non-food pesticide products, [EPA] Important intermediate in carbohydrate metabolism in mammals, Used for industrial cleaning, metal surface treatment, textile bleach stabilizing, aluminum processing, and as a chelating agent in cement set retarding, cleaning products, personal care products, pharmaceuticals, and foods, [OECD SIDS: Gluconic acid and its derivatives - 2004], Aluminum Producing [Category: Industry], Acid and Alkali Cleaning of Metals [Category: Clean], Textiles (Fiber & Fabric Manufacturing) [Category: Industry], Cement Producing [Category: Industry], Textiles (Printing, Dyeing, or Finishing) [Category: Industry], Component of many cleaning compounds because of the sequestering ability of the gluconate radical which remains active in alkaline solutions, in the dairy industry to prevent milkstone, in breweries to prevent beerstone, as latent acid catalyst for acid colloid resins, particularly in textile printing, as a coagulant for tofu., Sequestering agent, Food additive, Medication (Vet), Use Classification: EPA Safer Chemical Functional Use Classes -> Preservatives and Antioxidants, Processing Aids and Additives, Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern, Food Additives -> ACID, ACIDITY_REGULATOR, RAISING_AGENT, SEQUESTRANT -> JECFA Functional Classes, Cosmetics -> Skin conditioning, Solvent, Humectant, Industry Uses: Processing aids not otherwise specified, Not Known or Reasonably Ascertainable, Intermediate, Chelating agent, Consumer Uses: Processing aids not otherwise specified, Household Products: Information on 41 consumer products that contain Gluconolactone in the following categories is provided:, • Inside the Home, • Personal Care, • Pet Care, Methods of Manufacturing: By oxidation of glucose with bromine water ... by oxidation of glucose in Acetobacter suboxydans, Glucono-1, 5-lactone crystallizes from a supersaturated aqueous gluconic acid solution between 36 and 57 °C. A two-step continuous crystallization is said to result in increased productivity per unit volume under conditions that are favorable in terms of energy consumption. In the first step, a crystalline suspension (3 to 10 % crystalline material) is produced in a supersaturated gluconic acid solution held at 65 to 75 °C. The second step involves controlled cooling to 40 to 45 °C, followed by a period of crystal maturation at constant temperature. A portion of the resulting crystalline suspension is then recycled to the first step. ... The 1, 5-lactone may also be obtained from an aqueous gluconic acid solution by dehydration involving azeotropic distillation with alcohols, followed by crystallization from the alcohol-containing residue. Crystallization above 70 °C leads to the 1, 4-lactone., U.S. Production: 2023: 3, 750, 236 lb, 2022: 4, 124, 048 lb, 2021: 4, 439, 127 lb, 2020: 3, 657, 983 lb, This chemical is listed as a High Production Volume (HPV) (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and, or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B, 51FR21438)., (1986) >1 million - 10 million pounds, (1990) >1 million - 10 million pounds, (1994) >1 million - 10 million pounds, (2002) 10 thousand - 500 thousand pounds, General Manufacturing Information: Non-metallic Mineral Product Manufacturing (includes clay, glass, cement, concrete, lime, gypsum, and other non-metallic mineral product manufacturing), All Other Chemical Product and Preparation Manufacturing, All Other Basic Organic Chemical Manufacturing, D-Gluconic acid, .delta.-lactone: ACTIVE, Structure: J Stanek et al, The Monosaccharides (Academic Press, NY 1963) p 271., Glucono-delta-lactone is direct food additive limited by meat inspection div to use at, 8 oz, 100 lb of cured, comminuted meat or meat product to speed up color-fixing process & to reduce time required for smoking, must be listed in product ingredient statement..

Purchase Profile

What this product is

Gluconolactone is a carbon-based organic compound with CAS registry number 90-80-2 and molecular formula C6H10O6 (molecular weight 178.14), belonging to the organic chemicals segment of chemical raw materials.

Identification

CAS number: 90-80-2

Its molecular formula C6H10O6 comprises 6 C, 10 H, 6 O atoms.

Also known as: Gluconolactone · Glucono-δ-lactone USP26 FCCIV

Category: organic chemicals / chemical

Frequently Asked Questions

What is the CAS number of Gluconolactone?

The CAS registry number of Gluconolactone is 90-80-2.

What is the molecular formula and molecular weight of Gluconolactone?

Molecular formula C6H10O6, molecular weight 178.14.

What other names is Gluconolactone known by?

It is also registered under: Gluconolactone, Glucono-δ-lactone USP26 FCCIV.

What are the documented applications of Gluconolactone?

Recorded applications: Uses: CIR ingredient: Glucarolactone, CIR ingredient: Gluconolactone, Used in cleaning compounds, the dairy and brewery industries, textile printing, and tofu production (coagulant), [Merck Index] Used as a curing or pickling agent, flavoring agent, formulation aid, leavening agent, pH control agent, and sequestrant for foods, [FDA] Permitted for use as an inert ingredient in non-food pesticide products, [EPA] Important intermediate in carbohydrate metabolism in mammals, Used for industrial cleaning, metal surface treatment, textile bleach stabilizing, aluminum processing, and as a chelating agent in cement set retarding, cleaning products, personal care products, pharmaceuticals, and foods, [OECD SIDS: Gluconic acid and its derivatives - 2004], Aluminum Producing [Category: Industry], Acid and Alkali Cleaning of Metals [Category: Clean], Textiles (Fiber & Fabric Manufacturing) [Category: Industry], Cement Producing [Category: Industry], Textiles (Printing, Dyeing, or Finishing) [Category: Industry], Component of many cleaning compounds because of the sequestering ability of the gluconate radical which remains active in alkaline solutions, in the dairy industry to prevent milkstone, in breweries to prevent beerstone, as latent acid catalyst for acid colloid resins, particularly in textile printing, as a coagulant for tofu., Sequestering agent, Food additive, Medication (Vet), Use Classification: EPA Safer Chemical Functional Use Classes -> Preservatives and Antioxidants, Processing Aids and Additives, Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern, Food Additives -> ACID, ACIDITY_REGULATOR, RAISING_AGENT, SEQUESTRANT -> JECFA Functional Classes, Cosmetics -> Skin conditioning, Solvent, Humectant, Industry Uses: Processing aids not otherwise specified, Not Known or Reasonably Ascertainable, Intermediate, Chelating agent, Consumer Uses: Processing aids not otherwise specified, Household Products: Information on 41 consumer products that contain Gluconolactone in the following categories is provided:, • Inside the Home, • Personal Care, • Pet Care, Methods of Manufacturing: By oxidation of glucose with bromine water ... by oxidation of glucose in Acetobacter suboxydans, Glucono-1, 5-lactone crystallizes from a supersaturated aqueous gluconic acid solution between 36 and 57 °C. A two-step continuous crystallization is said to result in increased productivity per unit volume under conditions that are favorable in terms of energy consumption. In the first step, a crystalline suspension (3 to 10 % crystalline material) is produced in a supersaturated gluconic acid solution held at 65 to 75 °C. The second step involves controlled cooling to 40 to 45 °C, followed by a period of crystal maturation at constant temperature. A portion of the resulting crystalline suspension is then recycled to the first step. ... The 1, 5-lactone may also be obtained from an aqueous gluconic acid solution by dehydration involving azeotropic distillation with alcohols, followed by crystallization from the alcohol-containing residue. Crystallization above 70 °C leads to the 1, 4-lactone., U.S. Production: 2023: 3, 750, 236 lb, 2022: 4, 124, 048 lb, 2021: 4, 439, 127 lb, 2020: 3, 657, 983 lb, This chemical is listed as a High Production Volume (HPV) (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and, or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B, 51FR21438)., (1986) >1 million - 10 million pounds, (1990) >1 million - 10 million pounds, (1994) >1 million - 10 million pounds, (2002) 10 thousand - 500 thousand pounds, General Manufacturing Information: Non-metallic Mineral Product Manufacturing (includes clay, glass, cement, concrete, lime, gypsum, and other non-metallic mineral product manufacturing), All Other Chemical Product and Preparation Manufacturing, All Other Basic Organic Chemical Manufacturing, D-Gluconic acid, .delta.-lactone: ACTIVE, Structure: J Stanek et al, The Monosaccharides (Academic Press, NY 1963) p 271., Glucono-delta-lactone is direct food additive limited by meat inspection div to use at, 8 oz, 100 lb of cured, comminuted meat or meat product to speed up color-fixing process & to reduce time required for smoking, must be listed in product ingredient statement..

Which category does Gluconolactone belong to?

Category: Organic Chemicals / Stabilizers & Coagulants.

PubChem Public Data

Public-database records for Gluconolactone (CAS 90-80-2), reproduced here for independent cross-checking.

Safety classification and hazard statements

GHS notification summary98.7% (231 / 234)

This chemical does not meet GHS hazard criteria for 98.7% (231 of 234) of all reports.

Reported as not meeting GHS hazard criteria by 231 of 234 companies (only 1.3% companies provided GHS information). For more detailed information, please visit ECHA C&L website.

Regulatory listings

Regulatory & Food ContactFDA Substance added to food: CURING OR PICKLING AGENT, FLAVOR ENHANCER, FLAVORING AGENT OR ADJUVANT, FORMULAT
ACID; ACIDITY_REGULATOR; RAISING_AGENT; SEQUESTRANT: Food Additives
Glucono-delta-lactone is the cyclic 1,5-intramolecular ester of D-gluconic acid. In aqueous media it is hydrol
GLUCONO-DELTA LACTONE
CURING OR PICKLING AGENT, FLAVOR ENHANCER, FLAVORING AGENT OR ADJUVANT, FORMULATION AID, LEAVENING AGENT, PH C
NOT SPECIFIED
GHS notification summary98.7% (231 / 234)

Physical description and handling notes

  • Dry Powder; Other Solid
  • Fine, white, nearly odourless, crystalline powder
  • White solid; [HSDB] Crystals; [Alfa Aesar MSDS]
  • Solid
  • White crystals
  • Sweet taste

Reported physical properties

熔点155 °C /decomposes/
熔点151 - 155 °C
溶解度590000
溶解度In water, 5.9X10+5 mg/L at 25 °C
溶解度590.0 mg/mL
密度1.610 g/cu cm at -5 °C
Collision Cross Section144.7 Ų [M+Na]+
Collision Cross Section132.8 Ų [M-H+H2O]-

How this substance is indexed

CAS Registry Number90-80-2
PubChem CID7027
分子式C6H10O6
IUPAC 名称(3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-one
UNII(FDA)WQ29KQ9POT

Documented uses

  • Aluminum Producing [Category: Industry]
  • Acid and Alkali Cleaning of Metals [Category: Clean]
  • Textiles (Fiber & Fabric Manufacturing) [Category: Industry]
  • Cement Producing [Category: Industry]
  • Textiles (Printing, Dyeing, or Finishing) [Category: Industry]
  • Component of many cleaning compounds because of the sequestering ability of the gluconate radical which remains active in alkaline solutions; in the dairy industry to prevent milkstone; in breweries to prevent beerstone; as latent acid catalyst for acid colloid resins, particularly in textile printing; as a coagulant for tofu.

Names this substance appears under

gluconolactone; 90-80-2; delta-gluconolactone; D-glucono-1,5-lactone; Gluconic acid lactone; (3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-one; D-Gluconic acid lactone; D-Gluconic acid delta-lactone; 1,5-D-Gluconolactone; Gluconic lactone; (3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-one; Gluconic delta-lactone; delta-D-Gluconolactone; Glucono delta lactone; Deltagluconolactone; Fujiglucon

Computed molecular descriptors

分子量178.14
XLogP3-2
氢键供体数4
氢键受体数6
可旋转键数1
精确质量178.04773803
单同位素质量178.04773803
拓扑极性表面积107
重原子数12
形式电荷0

Database abstract

Gluconolactone · CAS 90-80-2 · C6H10O6. UNII WQ29KQ9POT. 熔点: 155 °C /decomposes/; 熔点: 151 - 155 °C; 溶解度: 590000.

Source: PubChem / Wikidata; the batch COA governs where values differ.

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