puromycin

Public-database records for puromycin (CAS 53-79-2), reproduced here for independent cross-checking.

Physical description and handling notes

• 197.6 Ų [M+H-H2O]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 203.92 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 212.55 Ų [M+K]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 210.53 Ų [M+Na]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

Reported physical properties

How this substance is indexed

Documented uses

• Antimetabolites that are useful in cancer chemotherapy.
• Compounds which inhibit the synthesis of proteins. They are usually ANTI-BACTERIAL AGENTS or toxins. Mechanism of the action of inhibition includes the interruption of peptide-chain elongation, the blocking the A site of ribosomes, the misreading of the genetic code or the prevention of the attachment of oligosaccharide side chains to glycoproteins.
• Agents destructive to the protozoal organisms belonging to the suborder TRYPANOSOMATINA.

Names this substance appears under

puromycin; 53-79-2; Stylomycin; Puromicina; Puromycine; Puromycinum; Stillomycin; P-638; 3123L; GNF-PF-2016; CL 13,900; CHEBI:17939; CL-13900; 4A6ZS6Q2CL; 3'-(L-alpha-Amino-p-methoxyhydrocinnamamido)-3'-deoxy-N,N-dimethyladenosine; CL 13900

Computed molecular descriptors

Database abstract

puromycin · CAS 53-79-2 · C22H29N7O5. UNII 4A6ZS6Q2CL. 熔点: 168°C-182°C; 溶解度: 50mg/ml; LogP: 0.85.

Source: PubChem / Wikidata; the batch COA governs where values differ.