2-Methylimidazole (CAS 693-98-1) — formula C4H6N2, molecular weight 82.10; category organic chemicals.
Documented applications: Uses: Used to make pharmaceuticals, photographic and photothermographic chemicals, dyes, pigments, agricultural chemicals, and rubber, Also used in epoxy resin systems for semiconductor potting compounds and soldering masks, as dyeing auxiliary for acrylic fibers and plastic foams, and in polymers such as epoxy resin pastes and acrylic rubber-fluororubber, [HSDB] Present in caramel coloring, tobacco smoke, wine, soy sauce, and other foods, Also formed when ammonia is added to livestock feed to increase nutritional value, Used in various polymers including acrylic rubber-fluororubber laminates, films, adhesives, textile finishes, and epoxy silane coatings, [NTP], Semiconductor Manufacturing [Category: Industry], Working with Glues and Adhesives [Category: Other], Plastic Composites Manufacturing [Category: Industry], Textiles (Printing, Dyeing, or Finishing) [Category: Industry], Dyeing auxiliary for acrylic fibers, plastic foams, Used in the manufacture of pharmaceuticals, agricultural chemicals and rubber, Used in epoxy resin systems for semiconductor potting compounds and soldering masks, Component of polymers including epoxy resin pastes, acrylic rubber-fluororubber, Industry Uses: Hardener, Intermediate, Catalyst, Not Known or Reasonably Ascertainable, Consumer Uses: Hardener, Methods of Manufacturing: In the generally applicable Radziszewski reaction, a 1, 2-dicarbonyl compound is condensed with an aldehyde and ammonia (R1 = H) in a molar ratio of 1:1:2, respectively. Replacement of a molar equivalent of ammonia with a primary amine (R1 = alkyl or aryl) leads to the corresponding 1-substituted imidazoles. The reaction is usually carried out in water or a water-alcohol mixture at 50 - 100 °C. Work-up may involve the usual processes (e.g., distillation, extraction, and crystallization). Distillation leads to imidazole with a purity > 99%. The yield is generally 60 - 85 %. ... Compounds used to prepare simple imidazoles by the Radziszewski reaction: Imidazole: 2-methylimidazole, Dicarbonyl compound: glyoxal, Aldehyde: acetaldehyde, Amine: ammonia., U.S. Production: 2023: 50, 000 - <75, 000 lb, 2022: 250, 000 - <550, 2021: 100, 000 - <250, 2020: 250, Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#7424], General Manufacturing Information: Paint and Coating Manufacturing, All Other Basic Organic Chemical Manufacturing, 1H-Imidazole, 2-methyl-: ACTIVE.
2-Methylimidazole is a carbon-based organic compound with CAS registry number 693-98-1 and molecular formula C4H6N2 (molecular weight 82.10), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 693-98-1
Its molecular formula C4H6N2 comprises 4 C, 6 H, 2 N atoms.
Also known as: 2-Methylimidazole · Methylimidazole
Category: organic chemicals
The CAS registry number of 2-Methylimidazole is 693-98-1.
Molecular formula C4H6N2, molecular weight 82.10.
It is also registered under: 2-Methylimidazole, Methylimidazole.
Recorded applications: Uses: Used to make pharmaceuticals, photographic and photothermographic chemicals, dyes, pigments, agricultural chemicals, and rubber, Also used in epoxy resin systems for semiconductor potting compounds and soldering masks, as dyeing auxiliary for acrylic fibers and plastic foams, and in polymers such as epoxy resin pastes and acrylic rubber-fluororubber, [HSDB] Present in caramel coloring, tobacco smoke, wine, soy sauce, and other foods, Also formed when ammonia is added to livestock feed to increase nutritional value, Used in various polymers including acrylic rubber-fluororubber laminates, films, adhesives, textile finishes, and epoxy silane coatings, [NTP], Semiconductor Manufacturing [Category: Industry], Working with Glues and Adhesives [Category: Other], Plastic Composites Manufacturing [Category: Industry], Textiles (Printing, Dyeing, or Finishing) [Category: Industry], Dyeing auxiliary for acrylic fibers, plastic foams, Used in the manufacture of pharmaceuticals, agricultural chemicals and rubber, Used in epoxy resin systems for semiconductor potting compounds and soldering masks, Component of polymers including epoxy resin pastes, acrylic rubber-fluororubber, Industry Uses: Hardener, Intermediate, Catalyst, Not Known or Reasonably Ascertainable, Consumer Uses: Hardener, Methods of Manufacturing: In the generally applicable Radziszewski reaction, a 1, 2-dicarbonyl compound is condensed with an aldehyde and ammonia (R1 = H) in a molar ratio of 1:1:2, respectively. Replacement of a molar equivalent of ammonia with a primary amine (R1 = alkyl or aryl) leads to the corresponding 1-substituted imidazoles. The reaction is usually carried out in water or a water-alcohol mixture at 50 - 100 °C. Work-up may involve the usual processes (e.g., distillation, extraction, and crystallization). Distillation leads to imidazole with a purity > 99%. The yield is generally 60 - 85 %. ... Compounds used to prepare simple imidazoles by the Radziszewski reaction: Imidazole: 2-methylimidazole, Dicarbonyl compound: glyoxal, Aldehyde: acetaldehyde, Amine: ammonia., U.S. Production: 2023: 50, 000 - <75, 000 lb, 2022: 250, 000 - <550, 2021: 100, 000 - <250, 2020: 250, Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#7424], General Manufacturing Information: Paint and Coating Manufacturing, All Other Basic Organic Chemical Manufacturing, 1H-Imidazole, 2-methyl-: ACTIVE.
Category: Organic Chemicals.
Public-database records for 2-Methylimidazole (CAS 693-98-1), reproduced here for independent cross-checking.
| GHS notification summary | 8.4% (64 / 758) |
|---|---|
| Reported hazard statements | H302 (81.9%), H314 (87.3%), H318 (31.3%), H351 (26.9%), H360 (21.1%), H341, H371, H373 |
H360Df: May damage the unborn child; Suspected of damaging fertility [Danger Reproductive toxicity]
P203, P280, P318, P405, and P501 (click each P-code to see the statement)
| GHS notification summary | 8.4% (64 / 758) |
|---|
| 沸点 | 267 °C |
|---|---|
| 熔点 | 144 °C |
| 蒸气压 | 0.01 [mmHg] |
| LogP | log Kow = 0.24 |
| LogP | 0.24 |
| CAS Registry Number | 693-98-1 |
|---|---|
| PubChem CID | 12749 |
| 分子式 | C4H6N2 |
| IUPAC 名称 | 2-methyl-1H-imidazole |
| UNII（FDA） | T0049Z45LZ |
2-METHYLIMIDAZOLE; 693-98-1; 2-Methyl-1H-imidazole; 1H-Imidazole, 2-methyl-; DTXSID4022107; T0049Z45LZ; CUREZOL-2MZ-P; IMICURE-AMI 2; EPICURE-MI 2; EPIKURE-MI 2; NSC-21394; DTXCID202107; RefChem:88340; 211-765-7; Imidazole, 2-methyl-; 2-Methylglyoxaline
| 分子量 | 82.10 |
|---|---|
| XLogP3 | 0.2 |
| 氢键供体数 | 1 |
| 氢键受体数 | 1 |
| 可旋转键数 | 0 |
| 精确质量 | 82.053098200 |
| 单同位素质量 | 82.053098200 |
| 拓扑极性表面积 | 28.7 |
| 重原子数 | 6 |
| 形式电荷 | 0 |
2-Methylimidazole · CAS 693-98-1 · C4H6N2. UNII T0049Z45LZ. 沸点: 267 °C; 熔点: 144 °C; 蒸气压: 0.01 [mmHg].
Source: PubChem / Wikidata; the batch COA governs where values differ.
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