5-Hydroxymethylfurfural

Public-database records for 5-Hydroxymethylfurfural (CAS 67-47-0), reproduced here for independent cross-checking.

Safety classification and hazard statements

Regulatory listings

Physical description and handling notes

• Solid with an odor of chamomile flowers; mp = 31.5 deg C; [Merck Index] Beige or yellow hygroscopic solid; mp = 32-35 deg C; [Alfa Aesar MSDS]
• Solid
• Crystalline solid (needles)
• Needles (ethyl ether-petroleum ether)
• Odor of chamomile flowers
• Butter, caramel, musty

Reported physical properties

How this substance is indexed

Documented uses

• Used to make dialdehydes, glycols, ethers, aminoalcohols, and acetals; [Merck Index] A flavoring agent that naturally occurs in some foods and alcoholic beverages; [ExPub: EFSA] Renewable building block for organic syntheses. [HSDB] Formed when sugars such as fructose or glucose are heated in the presence of amino acids, and is ubiquitous in the diet; Also used to make phenol/furfural resins; [NTP]
• In the synthesis of dialdehydes, glycols, ethers, amino alcohols, acetals. Aqueous acid catalyzes ring opening.
• Formation of 5-hydroxymethyl-2-furfuraldehyde can be used as an index of excessive heat treatment and of deteriorative changes in food
• Renewable building block for organic syntheses
• The acid-catalyzed dehydration of hexoses results in the formation of 5-hydroxymethylfurfural (HMF). Fructose and insulin are especially good starting materials.
• ... From fructose or inulin hydrolysates by acid-induced elimination of three molecular equivalents of water.

Names this substance appears under

5-HYDROXYMETHYLFURFURAL; 67-47-0; 5-Hydroxymethyl-2-furaldehyde; 5-(Hydroxymethyl)furfural; 5-(Hydroxymethyl)-2-furaldehyde; 5-Oxymethylfurfurole; Hydroxymethylfurfurole; Hydroxymethylfurfuraldehyde; 5-(Hydroxymethyl)-2-furancarbonal; 2-Furancarboxaldehyde, 5-(hydroxymethyl)-; 5-Hydroxymethylfuran-2-aldehyde; 5-Hydroxymethyl-2-formylfuran; Hydroxymethylfurfuralaldehyde; 2-Hydroxymethyl-5-furfural; 5-hydroxymethyl furfural; 5-(Hydroxymethyl)-2-furfuraldehyde

Computed molecular descriptors

Database abstract

5-Hydroxymethylfurfural · CAS 67-47-0 · C6H6O3. UNII 70ETD81LF0. 沸点: BP: 115 °C at 1 mm Hg; 沸点: 114.00 to 116.00 °C. @ 1.00 mm Hg; 熔点: 31.5 °C.

Source: PubChem / Wikidata; the batch COA governs where values differ.