2,2'-(4-(2-hydroxyethylamino)-3-nitro-phenylimino) (CAS 33229-34-4) — formula C12H19N3O5, molecular weight 285.30; category organic chemicals.
Documented applications: Uses: CIR ingredient: HC Blue No. 2, Used as a dye in semi-permanent hair dye formulations, Not commercially produced in the US, [HSDB], Dressing Hair [Category: Other], HC Blue #2 is used exclusively as a dye in semi-permanent hair coloring products. The concentration of HC Blue #2 used in these preparations ranges from 1.6-2%., Use Classification: Cosmetics -> Hair dyeing, Household Products: Information on 15 consumer products that contain HC Blue No 2 in the following categories is provided:, • Personal Care, Methods of Manufacturing: HC Blue #2 that is greater than or equal to 95% pure is produced commercially by the reaction of 4-fluoro-3-nitrobenzenamine with ethylene oxide to form 2, 2-(4-fluoro-3-nitrophenyl)imino)bis(ethanol), this intermediate is reacted with monoethanolamine to form HC Blue #2., The technical grade is produced by reaction of 2-nitro-p-phenylenediamine with ethylene oxide or 2-chloroethanol., Impurities: HC Blue #2 is available commercially with a purity greater than or equal to 95% with possible impurities, including methylamine (<1%), 1, 2-dihydroxyethane (<1%), and water (<1%). It is also available in a technical grade containing 55-90% dye, 10-30% inorganic salts and 2, 2-((4-amino-3-nitrophenyl)imino)bis (ethanol) (<7%) as a possible impurity., U.S. Production: (1977) NOT PRODUCED COMMERCIALLY IN US, (1979) NOT PRODUCED COMMERCIALLY IN US, General Manufacturing Information: Production and use of HC Blue #2 began in the late 1950s. Approximately 9-11 tons are used annually in the USA, according to industry estimates..
2,2'-(4-(2-hydroxyethylamino)-3-nitro-phenylimino) is a carbon-based organic compound with CAS registry number 33229-34-4 and molecular formula C12H19N3O5 (molecular weight 285.30), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 33229-34-4
Its molecular formula C12H19N3O5 comprises 12 C, 19 H, 3 N, 5 O atoms.
Also known as: 2,2'-(4-(2-hydroxyethylamino)-3-nitro-phenylimino) · HC Blue 2
Category: organic chemicals
The CAS registry number of 2,2'-(4-(2-hydroxyethylamino)-3-nitro-phenylimino) is 33229-34-4.
Molecular formula C12H19N3O5, molecular weight 285.30.
It is also registered under: 2,2'-(4-(2-hydroxyethylamino)-3-nitro-phenylimino), HC Blue 2.
Recorded applications: Uses: CIR ingredient: HC Blue No. 2, Used as a dye in semi-permanent hair dye formulations, Not commercially produced in the US, [HSDB], Dressing Hair [Category: Other], HC Blue #2 is used exclusively as a dye in semi-permanent hair coloring products. The concentration of HC Blue #2 used in these preparations ranges from 1.6-2%., Use Classification: Cosmetics -> Hair dyeing, Household Products: Information on 15 consumer products that contain HC Blue No 2 in the following categories is provided:, • Personal Care, Methods of Manufacturing: HC Blue #2 that is greater than or equal to 95% pure is produced commercially by the reaction of 4-fluoro-3-nitrobenzenamine with ethylene oxide to form 2, 2-(4-fluoro-3-nitrophenyl)imino)bis(ethanol), this intermediate is reacted with monoethanolamine to form HC Blue #2., The technical grade is produced by reaction of 2-nitro-p-phenylenediamine with ethylene oxide or 2-chloroethanol., Impurities: HC Blue #2 is available commercially with a purity greater than or equal to 95% with possible impurities, including methylamine (<1%), 1, 2-dihydroxyethane (<1%), and water (<1%). It is also available in a technical grade containing 55-90% dye, 10-30% inorganic salts and 2, 2-((4-amino-3-nitrophenyl)imino)bis (ethanol) (<7%) as a possible impurity., U.S. Production: (1977) NOT PRODUCED COMMERCIALLY IN US, (1979) NOT PRODUCED COMMERCIALLY IN US, General Manufacturing Information: Production and use of HC Blue #2 began in the late 1950s. Approximately 9-11 tons are used annually in the USA, according to industry estimates..
Category: Organic Chemicals.
Public-database records for 2,2'-(4-(2-hydroxyethylamino)-3-nitro-phenylimino) (CAS 33229-34-4), reproduced here for independent cross-checking.
| GHS notification summary | 0.9% (1 / 116) |
|---|---|
| Reported hazard statements | H315 (50%), H317 (40.5%), H319 (50%), H335 (49.1%), H412 (18.1%) |
This chemical does not meet GHS hazard criteria for 0.9% (1 of 116) of reports.
H315 (50%): Causes skin irritation [Warning Skin corrosion/irritation]
| Regulatory & Food Contact | CIR / INCI: Cosmetic ingredients (HC Blue No. 2) -> CIR (Cosmetic Ingredient Review) CIR / INCI: Hair dyeing |
|---|---|
| GHS notification summary | 0.9% (1 / 116) |
| 熔点 | 182 to 194 °F (NTP, 1992) |
|---|---|
| 熔点 | 93-98 °C (98% pure) |
| LogP | Log P= 1.7 |
| CAS Registry Number | 33229-34-4 |
|---|---|
| PubChem CID | 36383 |
| 分子式 | C12H19N3O5 |
| IUPAC 名称 | 2-[4-[bis(2-hydroxyethyl)amino]-2-nitroanilino]ethanol |
| UNII（FDA） | 6C0EL1931V |
33229-34-4; HC Blue no. 2; HC Blue 2; DTXSID6020193; NCI-C54897; 6C0EL1931V; Ethanol, 2,2'-((4-((2-hydroxyethyl)amino)-3-nitrophenyl)imino)di-; DTXCID80193; N1,N4,N4-Tris(2-hydroxyethyl)-2-nitro-p-phenylenediamine; COVARINE BLUE W 6122; p-Phenylenediamine, 3-nitro-N(sup 1),N(sup 1),N(sup 4)-tris(2-hydroxyethyl)-; RefChem:145365; 251-410-3; 2,2'-[4-(2-Hydroxyethylamino)-3-nitrophenylimino]diethanol; 2,2'-((4-((2-Hydroxyethyl)amino)-3-nitrophenyl)azanediyl)diethanol; 2-[4-[bis(2-hydroxyethyl)amino]-2-nitroanilino]ethanol
| 分子量 | 285.30 |
|---|---|
| XLogP3 | 0.4 |
| 氢键供体数 | 4 |
| 氢键受体数 | 7 |
| 可旋转键数 | 8 |
| 精确质量 | 285.13247072 |
| 单同位素质量 | 285.13247072 |
| 拓扑极性表面积 | 122 |
| 重原子数 | 20 |
| 形式电荷 | 0 |
2,2'-(4-(2-hydroxyethylamino)-3-nitro-phenylimino) · CAS 33229-34-4 · C12H19N3O5. UNII 6C0EL1931V. 熔点: 182 to 194 °F (NTP, 1992); 熔点: 93-98 °C (98% pure); LogP: Log P= 1.7.
Source: PubChem / Wikidata; the batch COA governs where values differ.
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