Puromycin Dihydrochloride

Public-database records for Puromycin Dihydrochloride (CAS 58-58-2), reproduced here for independent cross-checking.

Safety classification and hazard statements

Physical description and handling notes

• Puromycin dihydrochloride is a white powder. (NTP, 1992)
• Soluble (NTP, 1992)
• 204.4 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

How this substance is indexed

Documented uses

• Antimetabolites that are useful in cancer chemotherapy.
• Compounds which inhibit the synthesis of proteins. They are usually ANTI-BACTERIAL AGENTS or toxins. Mechanism of the action of inhibition includes the interruption of peptide-chain elongation, the blocking the A site of ribosomes, the misreading of the genetic code or the prevention of the attachment of oligosaccharide side chains to glycoproteins.
• Agents destructive to the protozoal organisms belonging to the suborder TRYPANOSOMATINA.

Names this substance appears under

Puromycin dihydrochloride; 58-58-2; Puromycin hydrochloride; DTXSID7045861; P-638 DIHYDROCHLORIDE; CL 16,536; PGN54228S5; CL-13900 DIHYDROCHLORIDE; NSC-3055; CL-16536; DTXCID5025861; Adenosine, 3'-((2-amino-3-(4-methoxyphenyl)-1-oxopropyl)amino)-3'-deoxy-N,N-dimethyl-, dihydrochloride, (S)-; Adenosine, 3'-(alpha-amino-p-methoxyhydrocinnamamido)-3'-deoxy-N,N-dimethyl-, dihydrochloride, L-; RefChem:177306; 200-387-8; Puromycin 2HCl

Computed molecular descriptors

Database abstract

Puromycin Dihydrochloride · CAS 58-58-2 · C22H29N7O5.2ClH. UNII PGN54228S5.

Source: PubChem / Wikidata; the batch COA governs where values differ.