parentrovite (CAS 53262-66-1) — formula C6H8O6, molecular weight 176.12; category organic chemicals.
Documented applications: Uses: CIR ingredient: L-Ascorbic Acid, CIR ingredient: Ascorbic Acid, An antioxidant essential in the human diet, Used as an antioxidant for foods and therapeutic vitamin, [Merck Index] Used as an antioxidant and pH adjustor in cosmetics (over 75% in hair dyes and colors), for abscission of citrus fruit in harvesting, as a reducing agent in analytical chemistry, skin protectant, and UV sunscreen, [HSDB] Used in chemical synthesis, [IUCLID] Used as flavoring agent, antimicrobial agent, antioxidant, dough strengthener, nutritional supplement, pH control agent, sequestrant, and stabilizer or thickener for foods, [FDA] Permitted for use as an inert ingredient in non-food pesticide products, [EPA], Dietary supplement, As antimicrobial and antioxidant in foodstuffs, Nutrition, color fixing, flavoring and preservative in meats and other foods, oxidant in bread dough, abscission of citrus fruit in harvesting, reducing agent in analytical chemistry, The iron, calcium, and sodium salts are available for biochemical research., For more Uses (Complete) data for L-Ascorbic Acid (12 total), please visit the HSDB record page., Use Classification: EPA Safer Chemical Functional Use Classes -> Processing Aids and Additives, Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern, Fragrance Ingredients, Food Additives -> ANTIOXIDANT -> JECFA Functional Classes, Cosmetics -> Buffering, Antioxidant, Industry Uses: Intermediate, Not Known or Reasonably Ascertainable, Consumer Uses: Not Known or Reasonably Ascertainable, Anti-stain agent, Other, Household Products: Information on 30 consumer products that contain Ascorbic Acid (Vitamin C) in the following categories is provided:, • Personal Care, • Pet Care, Information on 252 consumer products that contain Ascorbic acid in the following categories is provided:, Methods of Manufacturing: The classical Reichstein - Grussner synthesis starts with reduction of D-glucose to D-sorbitol by hydrogenation over a nickel catalyst. The microbiological oxidation of D-sorbitol to L-sorbose is carried out with Acetobacter xylinum. On treatment of L-sorbose with acetone at low temperature in the presence of sulfuric acid, 2, 3:4, 6-di-O-isopropylidene-alpha-L-sorbofuranose is formed. The di-O-isopropylidenyl protection of the hydroxyl-groups at C-2, C-3 and C-4, C-6 allows high-yield oxidation to di-O-isopropylidene-2-ketogulonic acid, without over-oxidation or other side reactions. The oxidation is carried out with potassium permanganate in alkaline solution. Treatment of, di-O-isopropylidene-2-ketogulonic acid, with hot water affords 2-keto-L-gulonic acid, which is converted to L-ascorbic acid by heating in water at 100 °C (20% yield) or by esterification and treatment with sodium methoxide in methanol followed by acidification with hydrogen chloride, yielding ca. 70% of, L-ascorbic acid, . The overall yield of ascorbic acid from D-glucose is 15-18%., Impurities: Oxalic acid < 0.2%, Heavy metals (as Pb): < 10 mg, kg, Formulations, Preparations: Ascorbic Acid (various manufacturers) Injection: 500 mg, mL, In 50 mL vials. Ascor L 500 (McGuff) Injection: 500 mg, 0.025% EDTA. Preservative-free. In 50 mL., Ascorbic Acid (as Ascorbic Acid or Sodium Ascorbate): Bulk: Powder. Oral: Capsules, extended-release 250 mg 500 mg. Lozenges 60 mg, Solution 25 mg, drop, 100 mg, 500 mg, 5 mL. Tablets: 100 mg, 250 mg, 1 g. Tablets, chewable, 1 g. Tablets, extended-release: 500 mg, 1 g. 1.5 g. (Available from one or more manufacturer, distributor, and, or repackager by generic (nonproprietary) name.), Ascorbic acid and sodium ascorbate are also commercially available in combination with other vitamins, minerals, amino acids, analgesic-antipyretics, anticholinergics, antihistamines, anti-inflammatory agents, cerebral stimulants, cough suppressants, enzymes, expectorants, hormones, infant formulas, keratolytic agents, laxatives, protein supplements, sedatives, and sympathomimetics. For iv infusion, ascorbic acid or sodium ascorbate is also commercially available in combination with other vitamins in caloric and electrolyte solutions., Grades: USP, FCC[Lewis RJ Sr, Hawley's Condensed Chemical Dictionary 15th ed Wiley (2007), Consumption Patterns: CHEMICAL PROFILE: Ascorbic Acid. US End-use Pattern for Ascorbic Acid in 1986., Table: US End-use pattern for ascorbic acid in 1986. [Table#2222], CHEMICAL PROFILE: Ascorbic acid. US End-use Pattern for Ascorbic Acid in 1989., Table: US End-use pattern for ascorbic acid in 1989 [Table#2223], CHEMICAL PROFILE: Ascorbic acid. US End-use Pattern for Ascorbic Acid in 1992., Table: US End-use pattern for ascorbic acid in 1992 [Table#2224], CHEMICAL PROFILE: Ascorbic acid. US End-use Pattern for Ascorbic Acid in 1995., Table: US End-use pattern for ascorbic acid in 1995 [Table#2225], For more Consumption Patterns (Complete) data for L-Ascorbic Acid (12 total), U.S. Production: 2023: 400, 000 - <550, 000 lb, 2022: 700, 000 - <850, 2021: 700, 2020: 2, 500, 000 - <4, 000, (1972) 7.08 X 10+9 g, In 1979, ca 10, 000 metric tons, yr of L-ascorbic acid was produced., (1992) Europe > 20, 000 tons per year, World approx 46, CHEMICAL PROFILE: Ascorbic acid. US Production Capacity: 1986: 32 million pounds, year., For more U.S. Production (Complete) data for L-Ascorbic Acid (11 total), U.S. Imports: (1972) 2.5 X 10+9 g, (1975) 2.13X10+9 g (including salts), CHEMICAL PROFILE: Ascorbic acid. US Imports: 1989: about 13 million pounds., CHEMICAL PROFILE: Ascorbic acid. US Imports: 1992: roughly 8-12 million pounds., For more U.S. Imports (Complete) data for L-Ascorbic Acid (6 total), U.S. Exports: (1972) 2.27 X 10+8 g, (1975) 7.76 X 10+7 g, CHEMICAL PROFILE:.
parentrovite is a carbon-based organic compound with CAS registry number 53262-66-1 and molecular formula C6H8O6 (molecular weight 176.12), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 53262-66-1
Its molecular formula C6H8O6 comprises 6 C, 8 H, 6 O atoms.
Also known as: parentrovite · Ascorbic Acid (Vitamin C)
Category: organic chemicals
The CAS registry number of parentrovite is 53262-66-1.
Molecular formula C6H8O6, molecular weight 176.12.
It is also registered under: parentrovite, Ascorbic Acid (Vitamin C).
Recorded applications: Uses: CIR ingredient: L-Ascorbic Acid, CIR ingredient: Ascorbic Acid, An antioxidant essential in the human diet, Used as an antioxidant for foods and therapeutic vitamin, [Merck Index] Used as an antioxidant and pH adjustor in cosmetics (over 75% in hair dyes and colors), for abscission of citrus fruit in harvesting, as a reducing agent in analytical chemistry, skin protectant, and UV sunscreen, [HSDB] Used in chemical synthesis, [IUCLID] Used as flavoring agent, antimicrobial agent, antioxidant, dough strengthener, nutritional supplement, pH control agent, sequestrant, and stabilizer or thickener for foods, [FDA] Permitted for use as an inert ingredient in non-food pesticide products, [EPA], Dietary supplement, As antimicrobial and antioxidant in foodstuffs, Nutrition, color fixing, flavoring and preservative in meats and other foods, oxidant in bread dough, abscission of citrus fruit in harvesting, reducing agent in analytical chemistry, The iron, calcium, and sodium salts are available for biochemical research., For more Uses (Complete) data for L-Ascorbic Acid (12 total), please visit the HSDB record page., Use Classification: EPA Safer Chemical Functional Use Classes -> Processing Aids and Additives, Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern, Fragrance Ingredients, Food Additives -> ANTIOXIDANT -> JECFA Functional Classes, Cosmetics -> Buffering, Antioxidant, Industry Uses: Intermediate, Not Known or Reasonably Ascertainable, Consumer Uses: Not Known or Reasonably Ascertainable, Anti-stain agent, Other, Household Products: Information on 30 consumer products that contain Ascorbic Acid (Vitamin C) in the following categories is provided:, • Personal Care, • Pet Care, Information on 252 consumer products that contain Ascorbic acid in the following categories is provided:, Methods of Manufacturing: The classical Reichstein - Grussner synthesis starts with reduction of D-glucose to D-sorbitol by hydrogenation over a nickel catalyst. The microbiological oxidation of D-sorbitol to L-sorbose is carried out with Acetobacter xylinum. On treatment of L-sorbose with acetone at low temperature in the presence of sulfuric acid, 2, 3:4, 6-di-O-isopropylidene-alpha-L-sorbofuranose is formed. The di-O-isopropylidenyl protection of the hydroxyl-groups at C-2, C-3 and C-4, C-6 allows high-yield oxidation to di-O-isopropylidene-2-ketogulonic acid, without over-oxidation or other side reactions. The oxidation is carried out with potassium permanganate in alkaline solution. Treatment of, di-O-isopropylidene-2-ketogulonic acid, with hot water affords 2-keto-L-gulonic acid, which is converted to L-ascorbic acid by heating in water at 100 °C (20% yield) or by esterification and treatment with sodium methoxide in methanol followed by acidification with hydrogen chloride, yielding ca. 70% of, L-ascorbic acid, . The overall yield of ascorbic acid from D-glucose is 15-18%., Impurities: Oxalic acid < 0.2%, Heavy metals (as Pb): < 10 mg, kg, Formulations, Preparations: Ascorbic Acid (various manufacturers) Injection: 500 mg, mL, In 50 mL vials. Ascor L 500 (McGuff) Injection: 500 mg, 0.025% EDTA. Preservative-free. In 50 mL., Ascorbic Acid (as Ascorbic Acid or Sodium Ascorbate): Bulk: Powder. Oral: Capsules, extended-release 250 mg 500 mg. Lozenges 60 mg, Solution 25 mg, drop, 100 mg, 500 mg, 5 mL. Tablets: 100 mg, 250 mg, 1 g. Tablets, chewable, 1 g. Tablets, extended-release: 500 mg, 1 g. 1.5 g. (Available from one or more manufacturer, distributor, and, or repackager by generic (nonproprietary) name.), Ascorbic acid and sodium ascorbate are also commercially available in combination with other vitamins, minerals, amino acids, analgesic-antipyretics, anticholinergics, antihistamines, anti-inflammatory agents, cerebral stimulants, cough suppressants, enzymes, expectorants, hormones, infant formulas, keratolytic agents, laxatives, protein supplements, sedatives, and sympathomimetics. For iv infusion, ascorbic acid or sodium ascorbate is also commercially available in combination with other vitamins in caloric and electrolyte solutions., Grades: USP, FCC[Lewis RJ Sr, Hawley's Condensed Chemical Dictionary 15th ed Wiley (2007), Consumption Patterns: CHEMICAL PROFILE: Ascorbic Acid. US End-use Pattern for Ascorbic Acid in 1986., Table: US End-use pattern for ascorbic acid in 1986. [Table#2222], CHEMICAL PROFILE: Ascorbic acid. US End-use Pattern for Ascorbic Acid in 1989., Table: US End-use pattern for ascorbic acid in 1989 [Table#2223], CHEMICAL PROFILE: Ascorbic acid. US End-use Pattern for Ascorbic Acid in 1992., Table: US End-use pattern for ascorbic acid in 1992 [Table#2224], CHEMICAL PROFILE: Ascorbic acid. US End-use Pattern for Ascorbic Acid in 1995., Table: US End-use pattern for ascorbic acid in 1995 [Table#2225], For more Consumption Patterns (Complete) data for L-Ascorbic Acid (12 total), U.S. Production: 2023: 400, 000 - <550, 000 lb, 2022: 700, 000 - <850, 2021: 700, 2020: 2, 500, 000 - <4, 000, (1972) 7.08 X 10+9 g, In 1979, ca 10, 000 metric tons, yr of L-ascorbic acid was produced., (1992) Europe > 20, 000 tons per year, World approx 46, CHEMICAL PROFILE: Ascorbic acid. US Production Capacity: 1986: 32 million pounds, year., For more U.S. Production (Complete) data for L-Ascorbic Acid (11 total), U.S. Imports: (1972) 2.5 X 10+9 g, (1975) 2.13X10+9 g (including salts), CHEMICAL PROFILE: Ascorbic acid. US Imports: 1989: about 13 million pounds., CHEMICAL PROFILE: Ascorbic acid. US Imports: 1992: roughly 8-12 million pounds., For more U.S. Imports (Complete) data for L-Ascorbic Acid (6 total), U.S. Exports: (1972) 2.27 X 10+8 g, (1975) 7.76 X 10+7 g, CHEMICAL PROFILE:.
Category: Organic Chemicals.
Public-database records for parentrovite (CAS 53262-66-1), reproduced here for independent cross-checking.
| GHS 通报统计 | 97.3% (572 / 588) |
|---|
| 法规与食品接触 | FDA Substance added to food: ANTIMICROBIAL AGENT, ANTIOXIDANT, COLOR OR COLORING ADJUNCT, DOUGH STRENGTHENER, ANTIOXIDANT: Food Additives ANTIMICROBIAL AGENT, ANTIOXIDANT, COLOR OR COLORING ADJUNCT, DOUGH STRENGTHENER, FLAVOR ENHANCER, FLAVORING AG 维生素 C（水果和蔬菜衍生） 旨在用作按照 wi 使用的其他市售形式的抗坏血酸的替代品 Scientific procedures |
|---|---|
| GHS 通报统计 | 97.3% (572 / 588) |
| 熔点 | 191 |
|---|---|
| 熔点 | 191 °C |
| 溶解度 | 400000 |
| 溶解度 | 400 mg/mL at 40 °C |
| 密度 | 1.65 g/cu cm at 25 °C |
| 密度 | 密度 (at 25 °C): 1.65 g/cm³ |
| LogP | -1.85 |
| LogP | log Kow = -1.85 |
| LogP | -2.15 |
| LogP | -1.84 |
| CAS 号 | 53262-66-1 |
|---|---|
| PubChem CID | 54670067 |
| 分子式 | C6H8O6 |
| IUPAC 名称 | (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one |
| UNII（FDA） | PQ6CK8PD0R |
| FEMA 编号 | 2109 |
l-ascorbic acid; ascorbic acid; vitamin C; 50-81-7; L(+)-Ascorbic acid; Ascoltin; Ascorbicap; Cevitamic acid; Allercorb; Ascorbajen; Ascorin; Ascorteal; Ascorvit; Cantaxin; Cebicure; Cegiolan
| 分子量 | 176.12 |
|---|---|
| XLogP3 | -1.6 |
| 氢键供体数 | 4 |
| 氢键受体数 | 6 |
| 可旋转键数 | 2 |
| 精确质量 | 176.03208797 |
| 单同位素质量 | 176.03208797 |
| 拓扑极性表面积 | 107 |
| 重原子数 | 12 |
| 形式电荷 | 0 |
母石 · CAS 53262-66-1 · C6H8O6. UNII PQ6CK8PD0R. 熔点: 191; 熔点: 191 °C; 溶解度: 400000.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd. · Reply within one business day.