oxprenolol（CAS 6452-73-9）的公开数据库记录，列此仅供独立核对。
危险化学品分类与危害说明
| GHS notification summary | 20% (1 / 5) |
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| Reported hazard statements | H301 (60%), H302 (20%), H412 (20%) |
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This chemical does not meet GHS hazard criteria for 20% (1 of 5) of reports.
H301 (60%): Toxic if swallowed [Danger Acute toxicity, oral]
法规与备案状态
| GHS notification summary | 20% (1 / 5) |
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这个物质在各数据库里的编号
| CAS Registry Number | 6452-73-9 |
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| PubChem CID | 71172 |
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| 分子式 | C15H24ClNO3 |
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| IUPAC 名称 | 1-(propan-2-ylamino)-3-(2-prop-2-enoxyphenoxy)propan-2-ol;hydrochloride |
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| UNII（FDA） | F4XSI7SNIU |
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数据库记载的用途
- Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety.
- Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.
- Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
- Drugs that inhibit the actions of the sympathetic nervous system by any mechanism. The most common of these are the ADRENERGIC ANTAGONISTS and drugs that deplete norepinephrine or reduce the release of transmitters from adrenergic postganglionic terminals (see ADRENERGIC AGENTS). Drugs that act in the central nervous system to reduce sympathetic activity (e.g., centrally acting alpha-2 adrenergic agonists, see ADRENERGIC ALPHA-AGONISTS) are included here.
- Agents that alleviate ANXIETY, tension, and ANXIETY DISORDERS, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. ADRENERGIC BETA-ANTAGONISTS are commonly used in the symptomatic treatment of anxiety but are not included here.
- Drugs used to cause dilation of the blood vessels.
它在各数据库里的别名
Oxprenolol hydrochloride; 6452-73-9; Oxprenolol HCl; Slow-Trasicor; Ba-39089; DTXSID5021093; F4XSI7SNIU; 2-Propanol, 1-(o-allyloxyphenoxy)-3-isopropylamino-, hydrochloride; BA-39,089; 1-(o-Allyloxyphenoxy)-3-isopropylamino-2-propanol hydrochloride; DTXCID001093; 2-Propanol, 1-((1-methylethyl)amino)-3-(2-(2-propenyloxy)phenoxy)-, hydrochloride; Apsolox; Laracor; Paritane; Trasicor ret
计算机算出的分子描述符
| 分子量 | 301.81 |
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| 氢键供体数 | 3 |
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| 氢键受体数 | 4 |
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| 可旋转键数 | 9 |
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| 精确质量 | 301.1444713 |
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| 单同位素质量 | 301.1444713 |
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| 拓扑极性表面积 | 50.7 |
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| 重原子数 | 20 |
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| 形式电荷 | 0 |
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| 复杂度 | 246 |
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数据库摘要
oxprenolol · CAS 6452-73-9 · C15H24ClNO3. UNII F4XSI7SNIU.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
