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methylsulfinylmethane

CAS 67-68-5C2H6OSMW 78.01 g/mol

methylsulfinylmethane(CAS 67-68-5):分子式 C2H6OS、分子量 78.01 g/mol;类别 有机化学品。

规格参数

CAS号67-68-5
分子式C2H6OS
分子量78.01 g/mol
熔点65.3 °F (NTP, 1992)
沸点372 °F at 760 mmHg (NTP, 1992)
LogP-0.6
应用领域Uses: Used as a pharmaceutical、a solvent for polymerization and chemical extractions、a paint remover、a preservative for organ transplantation、Occurs naturally in ground water and in grains、vegetables、and many other foods、[CHEMINFO] Used as a solvent for many organic compounds、Also used in industrial cleaners、[HSDB]、Semiconductor Manufacturing [Category: Industry]、DMSO is not a nutritional supplement. It is used as a treatment for interstitial cystitis、and treatment must be performed by a qualified physician. DMSO is metabolized to methylsulfonylmethane、which is available as a nutritional supplement.、Vitrification has become common for cryopreservation of embryos. ...Extended exposure of embryos with both vitrification protocols showed that the DMSO-containing vitrification solutions did not lead to cell membrane damage and death as quickly as the DMSO-free vitrification solutions. To assess embryo viability、the authors recommend that vitrification of early embryos should be combined with extended culture and assessment of normal blastocyst development before transferring to patients.、Dimethyl sulfoxide (DMSO) is a molecule with a long history in pharmaceutics and is now well established as a penetration enhancer in topical pharmaceutical formulations. It is currently used for this purpose in diclofenac sodium topical solution (approved in the United States to treat signs and symptoms of osteoarthritis) and idoxuridine topical solution (approved in Europe for the treatment of herpes zoster). ... The clinical use of pharmaceutical-grade DMSO as a penetration enhancer is supported by the robust data that have accumulated over the past 3 decades demonstrating the favorable safety and tolerability profile. Dimethyl sulfoxide is a safe and effective mechanism for facilitating the transdermal delivery of both hydrophilic and lipophilic medications to provide localized drug delivery.、For dimethyl sulfoxide (USEPA、OPP Pesticide Code: 000177) there are 0 labels match.、SRP: Not registered for current use in the U.S.、but approved pesticide uses may change periodically and so federal、state and local authorities must be consulted for currently approved uses.、For more Uses (Complete) data for DIMETHYL SULFOXIDE (13 total)、please visit the HSDB record page.、Use (kg、approx.) in Germany (2009): >10000、Consumption (g per capita、approx.) in Germany (2009): 0.122、Excretion rate: 0.68、Calculated removal (%): 75.1、DMSO is an important polar aprotic solvent. In cryobiology DMSO has been used as a cryoprotectant and is still an important constituent of cryoprotectant vitrification mixtures used to preserve organs、tissues、and cell suspensions.[Wikipedia]、Use Classification: Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients、Fragrance Ingredients、Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes、Flavoring Agents -> JECFA Flavorings Index、SOLVENTS、Industry Uses: Laboratory chemicals、Etching agent、Not Known or Reasonably Ascertainable、Cleaning agent、Plating agent、Solvent、Consumer Uses: Solvent、Soil amendments (fertilizers)、Household Products: Information on 1 consumer products that contain Dimethyl sulfoxide in the following categories is provided:、• Home Maintenance、Methods of Manufacturing: In industry、DMSO is produced by catalytic oxidation of dimethyl sulfide with oxygen or by oxidation with nitrogen dioxide. The oxidation of dimethyl sulfide with oxygen at 7.2 MPa and 105 °C gives good yields of DMSO.、Obtained as a by-product of paper manufacture ... .、Oxidation of dimethyl sulfide with nitrogen tetroxide under anhydrous conditions、sulfide waste liquors.、Formulations、Preparations: Rimso-50 (Research Industries) Solution: 50% aqueous solution.、Dimethyl Sulfoxide (Bioniche)、Solution: 50% aqueous solution、U.S. Production: 2023: 2、500、000 - <4、000、000 lb、2022: 2、2021: 2、2020: 2、(1972) Probably greater than 4.54x10+5 g、(1975) probably greater than 4.54x10+5 g、Methane、sulfinylbis- is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and、or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B、51FR21438).、Production volumes for non-confidential chemicals reported under the Inventory Update Rule.[Table#221]、For more U.S. Production (Complete) data for DIMETHYL SULFOXIDE (6 total)、Computer and Electronic Product Manufacturing、Plastics Product Manufacturing、Transportation Equipment Manufacturing、Electrical Equipment、Appliance、and Component Manufacturing、Pharmaceutical and Medicine Manufacturing、All Other Basic Organic Chemical Manufacturing、Services、Machinery Manufacturing、Adhesive Manufacturing、Paint and Coating Manufacturing、Fabricated Metal Product Manufacturing、1、1'-sulfinylbis-: ACTIVE、FDA does not permit its use in horses or dogs intended for breeding purposes、nor in horses slaughtered for food.、Dimethyl sulfoxide is used in many paint removers and has many green characteristics. It has low toxicity、a high flash point、and is not a HAP nor listed under SARA 313. A risk associated with DMSO removers is that it is readily transported through the skin and may readily carry toxic compounds present with it.
类别Organic Chemicals

用途与场景

登记用途:Uses: Used as a pharmaceutical、a solvent for polymerization and chemical extractions、a paint remover、a preservative for organ transplantation、Occurs naturally in ground water and in grains、vegetables、and many other foods、[CHEMINFO] Used as a solvent for many organic compounds、Also used in industrial cleaners、[HSDB]、Semiconductor Manufacturing [Category: Industry]、DMSO is not a nutritional supplement. It is used as a treatment for interstitial cystitis、and treatment must be performed by a qualified physician. DMSO is metabolized to methylsulfonylmethane、which is available as a nutritional supplement.、Vitrification has become common for cryopreservation of embryos. ...Extended exposure of embryos with both vitrification protocols showed that the DMSO-containing vitrification solutions did not lead to cell membrane damage and death as quickly as the DMSO-free vitrification solutions. To assess embryo viability、the authors recommend that vitrification of early embryos should be combined with extended culture and assessment of normal blastocyst development before transferring to patients.、Dimethyl sulfoxide (DMSO) is a molecule with a long history in pharmaceutics and is now well established as a penetration enhancer in topical pharmaceutical formulations. It is currently used for this purpose in diclofenac sodium topical solution (approved in the United States to treat signs and symptoms of osteoarthritis) and idoxuridine topical solution (approved in Europe for the treatment of herpes zoster). ... The clinical use of pharmaceutical-grade DMSO as a penetration enhancer is supported by the robust data that have accumulated over the past 3 decades demonstrating the favorable safety and tolerability profile. Dimethyl sulfoxide is a safe and effective mechanism for facilitating the transdermal delivery of both hydrophilic and lipophilic medications to provide localized drug delivery.、For dimethyl sulfoxide (USEPA、OPP Pesticide Code: 000177) there are 0 labels match.、SRP: Not registered for current use in the U.S.、but approved pesticide uses may change periodically and so federal、state and local authorities must be consulted for currently approved uses.、For more Uses (Complete) data for DIMETHYL SULFOXIDE (13 total)、please visit the HSDB record page.、Use (kg、approx.) in Germany (2009): >10000、Consumption (g per capita、approx.) in Germany (2009): 0.122、Excretion rate: 0.68、Calculated removal (%): 75.1、DMSO is an important polar aprotic solvent. In cryobiology DMSO has been used as a cryoprotectant and is still an important constituent of cryoprotectant vitrification mixtures used to preserve organs、tissues、and cell suspensions.[Wikipedia]、Use Classification: Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients、Fragrance Ingredients、Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes、Flavoring Agents -> JECFA Flavorings Index、SOLVENTS、Industry Uses: Laboratory chemicals、Etching agent、Not Known or Reasonably Ascertainable、Cleaning agent、Plating agent、Solvent、Consumer Uses: Solvent、Soil amendments (fertilizers)、Household Products: Information on 1 consumer products that contain Dimethyl sulfoxide in the following categories is provided:、• Home Maintenance、Methods of Manufacturing: In industry、DMSO is produced by catalytic oxidation of dimethyl sulfide with oxygen or by oxidation with nitrogen dioxide. The oxidation of dimethyl sulfide with oxygen at 7.2 MPa and 105 °C gives good yields of DMSO.、Obtained as a by-product of paper manufacture ... .、Oxidation of dimethyl sulfide with nitrogen tetroxide under anhydrous conditions、sulfide waste liquors.、Formulations、Preparations: Rimso-50 (Research Industries) Solution: 50% aqueous solution.、Dimethyl Sulfoxide (Bioniche)、Solution: 50% aqueous solution、U.S. Production: 2023: 2、500、000 - <4、000、000 lb、2022: 2、2021: 2、2020: 2、(1972) Probably greater than 4.54x10+5 g、(1975) probably greater than 4.54x10+5 g、Methane、sulfinylbis- is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and、or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B、51FR21438).、Production volumes for non-confidential chemicals reported under the Inventory Update Rule.[Table#221]、For more U.S. Production (Complete) data for DIMETHYL SULFOXIDE (6 total)、Computer and Electronic Product Manufacturing、Plastics Product Manufacturing、Transportation Equipment Manufacturing、Electrical Equipment、Appliance、and Component Manufacturing、Pharmaceutical and Medicine Manufacturing、All Other Basic Organic Chemical Manufacturing、Services、Machinery Manufacturing、Adhesive Manufacturing、Paint and Coating Manufacturing、Fabricated Metal Product Manufacturing、1、1'-sulfinylbis-: ACTIVE、FDA does not permit its use in horses or dogs intended for breeding purposes、nor in horses slaughtered for food.、Dimethyl sulfoxide is used in many paint removers and has many green characteristics. It has low toxicity、a high flash point、and is not a HAP nor listed under SARA 313. A risk associated with DMSO removers is that it is readily transported through the skin and may readily carry toxic compounds present with it.。

采购档案

这个产品是什么

methylsulfinylmethane 是一种以碳骨架为基础的有机化合物,登记 CAS 号为 67-68-5,分子式 C2H6OS(分子量 78.01 g/mol),归属于有机化学品大类化工原料。

识别信息

登记 CAS 号:67-68-5

其分子式 C2H6OS 由 2 个碳、6 个氢、1 个氧、1 个硫 组成。

别名/同义词:methylsulfinylmethane · Dimethyl sulfoxide

所属分类:有机化学品

常见问题

methylsulfinylmethane 的 CAS 号是多少?

methylsulfinylmethane 的 CAS 登记号为 67-68-5。

methylsulfinylmethane 的分子式与分子量是多少?

分子式 C2H6OS,分子量 78.01 g/mol。

methylsulfinylmethane 还有哪些别名?

别名/同义词:methylsulfinylmethane、Dimethyl sulfoxide。

methylsulfinylmethane 的登记用途是什么?

登记用途:Uses: Used as a pharmaceutical、a solvent for polymerization and chemical extractions、a paint remover、a preservative for organ transplantation、Occurs naturally in ground water and in grains、vegetables、and many other foods、[CHEMINFO] Used as a solvent for many organic compounds、Also used in industrial cleaners、[HSDB]、Semiconductor Manufacturing [Category: Industry]、DMSO is not a nutritional supplement. It is used as a treatment for interstitial cystitis、and treatment must be performed by a qualified physician. DMSO is metabolized to methylsulfonylmethane、which is available as a nutritional supplement.、Vitrification has become common for cryopreservation of embryos. ...Extended exposure of embryos with both vitrification protocols showed that the DMSO-containing vitrification solutions did not lead to cell membrane damage and death as quickly as the DMSO-free vitrification solutions. To assess embryo viability、the authors recommend that vitrification of early embryos should be combined with extended culture and assessment of normal blastocyst development before transferring to patients.、Dimethyl sulfoxide (DMSO) is a molecule with a long history in pharmaceutics and is now well established as a penetration enhancer in topical pharmaceutical formulations. It is currently used for this purpose in diclofenac sodium topical solution (approved in the United States to treat signs and symptoms of osteoarthritis) and idoxuridine topical solution (approved in Europe for the treatment of herpes zoster). ... The clinical use of pharmaceutical-grade DMSO as a penetration enhancer is supported by the robust data that have accumulated over the past 3 decades demonstrating the favorable safety and tolerability profile. Dimethyl sulfoxide is a safe and effective mechanism for facilitating the transdermal delivery of both hydrophilic and lipophilic medications to provide localized drug delivery.、For dimethyl sulfoxide (USEPA、OPP Pesticide Code: 000177) there are 0 labels match.、SRP: Not registered for current use in the U.S.、but approved pesticide uses may change periodically and so federal、state and local authorities must be consulted for currently approved uses.、For more Uses (Complete) data for DIMETHYL SULFOXIDE (13 total)、please visit the HSDB record page.、Use (kg、approx.) in Germany (2009): >10000、Consumption (g per capita、approx.) in Germany (2009): 0.122、Excretion rate: 0.68、Calculated removal (%): 75.1、DMSO is an important polar aprotic solvent. In cryobiology DMSO has been used as a cryoprotectant and is still an important constituent of cryoprotectant vitrification mixtures used to preserve organs、tissues、and cell suspensions.[Wikipedia]、Use Classification: Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients、Fragrance Ingredients、Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes、Flavoring Agents -> JECFA Flavorings Index、SOLVENTS、Industry Uses: Laboratory chemicals、Etching agent、Not Known or Reasonably Ascertainable、Cleaning agent、Plating agent、Solvent、Consumer Uses: Solvent、Soil amendments (fertilizers)、Household Products: Information on 1 consumer products that contain Dimethyl sulfoxide in the following categories is provided:、• Home Maintenance、Methods of Manufacturing: In industry、DMSO is produced by catalytic oxidation of dimethyl sulfide with oxygen or by oxidation with nitrogen dioxide. The oxidation of dimethyl sulfide with oxygen at 7.2 MPa and 105 °C gives good yields of DMSO.、Obtained as a by-product of paper manufacture ... .、Oxidation of dimethyl sulfide with nitrogen tetroxide under anhydrous conditions、sulfide waste liquors.、Formulations、Preparations: Rimso-50 (Research Industries) Solution: 50% aqueous solution.、Dimethyl Sulfoxide (Bioniche)、Solution: 50% aqueous solution、U.S. Production: 2023: 2、500、000 - <4、000、000 lb、2022: 2、2021: 2、2020: 2、(1972) Probably greater than 4.54x10+5 g、(1975) probably greater than 4.54x10+5 g、Methane、sulfinylbis- is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and、or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B、51FR21438).、Production volumes for non-confidential chemicals reported under the Inventory Update Rule.[Table#221]、For more U.S. Production (Complete) data for DIMETHYL SULFOXIDE (6 total)、Computer and Electronic Product Manufacturing、Plastics Product Manufacturing、Transportation Equipment Manufacturing、Electrical Equipment、Appliance、and Component Manufacturing、Pharmaceutical and Medicine Manufacturing、All Other Basic Organic Chemical Manufacturing、Services、Machinery Manufacturing、Adhesive Manufacturing、Paint and Coating Manufacturing、Fabricated Metal Product Manufacturing、1、1'-sulfinylbis-: ACTIVE、FDA does not permit its use in horses or dogs intended for breeding purposes、nor in horses slaughtered for food.、Dimethyl sulfoxide is used in many paint removers and has many green characteristics. It has low toxicity、a high flash point、and is not a HAP nor listed under SARA 313. A risk associated with DMSO removers is that it is readily transported through the skin and may readily carry toxic compounds present with it.。

methylsulfinylmethane 属于哪个分类?

所属分类:Organic Chemicals。

PubChem 公开数据

methylsulfinylmethane(CAS 67-68-5)的公开数据库记录,列此仅供独立核对。

危险化学品分类与危害说明

GHS notification summary65.1% (611 / 938)
Reported hazard statementsH315 (28.4%), H319 (33.6%), H335 (13.8%), H227, H371

This chemical does not meet GHS hazard criteria for 65.1% (611 of 938) of all reports.

H315 (28.4%): Causes skin irritation [Warning Skin corrosion/irritation]

法规与备案状态

Regulatory & Food ContactEU Flavoring substances
FDA Substance added to food: FLAVORING AGENT OR ADJUVANT
FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS
Flavoring Agents
FLAVOURING_AGENT: Flavouring Agent
Garlic
GHS notification summary65.1% (611 / 938)

物理形态与操作说明

  • Dimethyl sulfoxide appears as a clear liquid, essentially odorless. Closed cup flash point 192 °F. Vapors are heavier than air. Contact with the skin may cause stinging and burning and lead to an odor of garlic on the breath. An excellent solvent that can transport toxic solutes through the skin. High vapor concentrations may cause headache, dizziness, and sedation.
  • Liquid
  • Colorless liquid that is odorless or has a slight odor of sulfur, garlic, or oysters; [CHEMINFO]
  • COLOURLESS HYGROSCOPIC LIQUID.
  • colourless liquid with mild cabbage or garlic odour
  • Colorless liquid

公开数据库收录的理化数据

沸点372 °F at 760 mmHg (NTP, 1992)
沸点63
沸点189 °C
沸点189.00 to 190.00 °C. @ 760.00 mm Hg
沸点189 °C @760 [mm Hg]
熔点65.3 °F (NTP, 1992)
熔点18.5
熔点18.45 °C
熔点18.5 °C
熔点17.89 °C

这个物质在各数据库里的编号

CAS Registry Number67-68-5
PubChem CID679
分子式C2H6OS
分子量78.01 g/mol
IUPAC 名称methylsulfinylmethane
InChIKeyIAZDPXIOMUYVGZ-UHFFFAOYSA-N
UNII(FDA)YOW8V9698H
ChEBI 编号CHEBI:28262
ATC code (WHO)G04BX13
FEMA 编号3875
JECFA 编号507

数据库记载的用途

  • Used as a pharmaceutical, a solvent for polymerization and chemical extractions, a paint remover, a preservative for organ transplantation; Occurs naturally in ground water and in grains, vegetables, and many other foods; [CHEMINFO] Used as a solvent for many organic compounds; Also used in industrial cleaners; [HSDB]
  • Semiconductor Manufacturing [Category: Industry]
  • DMSO is not a nutritional supplement. It is used as a treatment for interstitial cystitis, and treatment must be performed by a qualified physician. DMSO is metabolized to methylsulfonylmethane, which is available as a nutritional supplement.
  • Vitrification has become common for cryopreservation of embryos. ...Extended exposure of embryos with both vitrification protocols showed that the DMSO-containing vitrification solutions did not lead to cell membrane damage and death as quickly as the DMSO-free vitrification solutions. To assess embryo viability, the authors recommend that vitrification of early embryos should be combined with extended culture and assessment of normal blastocyst development before transferring to patients.
  • For more Uses (Complete) data for DIMETHYL SULFOXIDE (13 total), please visit the HSDB record page.
  • Use (kg; approx.) in Germany (2009): >10000

它在各数据库里的别名

dimethyl sulfoxide; 67-68-5; DMSO; Methylsulfinylmethane; Methyl sulfoxide; Dimethyl sulphoxide; Dimethylsulfoxide; sulfinylbismethane; Demasorb; Domoso; Methane, sulfinylbis-; Demsodrox; Dromisol; Deltan; Demavet; Demeso

计算机算出的分子描述符

分子量78.14
XLogP3-0.6
氢键供体数0
氢键受体数2
可旋转键数0
精确质量78.01393598
单同位素质量78.01393598
拓扑极性表面积36.3
重原子数4
形式电荷0

数据库摘要

methylsulfinylmethane is identified by CAS 67-68-5, molecular formula C2H6OS and molecular weight 78.01 g/mol. UNII YOW8V9698H; ChEBI 28262; InChIKey IAZDPXIOMUYVGZ-UHFFFAOYSA-N. 沸点: 372 °F at 760 mmHg (NTP, 1992); 沸点: 63; 沸点: 189 °C.

数据来源:PubChem / Wikidata;与随货 COA 不一致时以 COA 为准。

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