Disodium Etidronate (HEDP-Na2)

Public-database records for Disodium Etidronate (HEDP-Na2) (CAS 7414-83-7), reproduced here for independent cross-checking.

Safety classification and hazard statements

Regulatory listings

How this substance is indexed

Documented uses

• CIR ingredient: Disodium Etidronate
• For the treatment of symptomatic Paget's disease of bone and in the prevention and treatment of heterotopic ossification following total hip replacement or due to spinal cord injury.
• Information on 1 consumer products that contain Disodium Etidronate in the following categories is provided:
• Phosphonic acid, P,P'-(1-hydroxyethylidene)bis-, sodium salt (1:2): ACTIVE
• Agents that inhibit BONE RESORPTION and/or favor BONE MINERALIZATION and BONE REGENERATION. They are used to heal BONE FRACTURES and to treat METABOLIC BONE DISEASES such as OSTEOPOROSIS.
• Not metabolized. Route of Elimination: Etidronate disodium is not metabolized. Within 24 hours, approximately half the absorbed dose is excreted in urine; the remainder is distributed to bone compartments from which it is slowly eliminated. Unabsorbed drug is excreted intact in the feces. Half Life: In normal subjects, plasma half-life of etidronic acid, based on non-compartmental pharmacokinetics is 1 to 6 hours.

Names this substance appears under

Etidronate disodium; 7414-83-7; Disodium etidronate; Sodium etidronate; Disodium ethydronate; Sodium ethidronate; Sodium ethydronate; Etidronic Acid Disodium Salt; Turpinal 2NZ; Disodium ethanol-1,1-diphosphonate; DTXSID1029671; Disodium 1-hydroxyethylidene phosphonate; Disodium (1-hydroxyethylidene)diphosphonate; Disodium dihydrogen (1-hydroxyethylidene)diphosphonate; Disodium ethane-1-hydroxy-1,1-diphosphonate; Phosphonic acid, (1-hydroxyethylidene)bis-, disodium salt

Computed molecular descriptors

Database abstract

Disodium Etidronate (HEDP-Na2) · CAS 7414-83-7 · C2H6Na2O7P2. UNII M16PXG993G.

Source: PubChem / Wikidata; the batch COA governs where values differ.