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1-Hexadecanol

CAS 36653-82-4C16H34OMW 242.26 g/mol

1-Hexadecanol (CAS 36653-82-4) — formula C16H34O, molecular weight 242.26 g/mol.

Specifications

CAS Number36653-82-4
Molecular FormulaC16H34O
Molecular Weight242.26 g/mol
Melting Point49.3
Boiling Point344
LogP7.3
ApplicationsUses: CIR ingredient: Cetyl Alcohol, Used in cosmetics, pharmaceuticals, perfumes, and shampoos (emollient and emulsion modifier) and to make face creams, lotions, lipsticks, toilet preparations, and antiperspirant sticks, Also used as a coupling agent, foam stabilizer in detergents, base for making sulfonated fatty acids, monomer lubricant in suspension polymerization, and to retard evaporation of water when spread as a film on reservoirs or sprayed on growing plants, [HSDB], Dressing Hair [Category: Other], For Cetyl Alcohol (USEPA, OPP Pesticide Code: 001508) there are 0 labels match., SRP: Not registered for current use in the U.S., but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses., The active ingredient is no longer contained in any registered pesticide products ... "cancelled.", In cosmetics as emollient, emulsion modifier, coupling agent. Pharmaceutical aid (emulsifying and stiffening agent)., Perfumery, emulsifier, emollient, face creams, chemical intermediate, detergents, cosmetics, to retard evaporation of water when spread as a film on reservoirs or sprayed on growing plants, For more Uses (Complete) data for 1-HEXADECANOL (10 total), please visit the HSDB record page., Use Classification: Fragrance Ingredients, Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes, Flavoring Agents -> JECFA Flavorings Index, Plastics -> Polymer Type -> N.a., Cosmetics -> Opacifying, Emulsifying, Skin conditioning, Emollient, Viscosity controlling, Plastics -> Other stabilisers, Industry Uses: Stabilizing agent, Thickening agent, Not Known or Reasonably Ascertainable, Intermediate, Solvent, Other, Lubricating agent, Surfactant (surface active agent), Consumer Uses: Not Known or Reasonably Ascertainable, Opacifer, Household Products: Information on 1 consumer products that contain Hexadecanol in the following categories is provided:, • Personal Care, Information on 959 consumer products that contain Cetyl alcohol in the following categories is provided:, • Commercial, Institutional, • Inside the Home, • Pesticides, • Pet Care, Methods of Manufacturing: Catalytic hydrogenation of the triglycerides obtained from coconut oil or tallow, oxidation of a chain growth product of ethylene oligomerized on a triethylaluminum catalyst, Prepared from palmitoyl chloride plus sodium borohydride ... from methylthiopalmitate plus Raney nickel: Ruzicka, Prelog, US patent 2, 509, 171 (1950 to Ciba), from hexadecyl bromide: Levine, Clippinger, US 3, 018, 308 (1962 to California Res. Corp.)., By saponifying spermaceti with caustic alkali, reduction of palmitic acid, Formulations, Preparations: Grades: Technical, cosmetic, national formulary., A typical anionic and cationic based all purpose face, head and body lotion contains 1% cetyl alcohol, Present in a popular cosmetic cream at 3%, Present in a typical depilatory formula at 6.15 wt%, National Formulary, natural, synthetic grades, flaked form, Flake, Cosmetic Fragerances Toiletries Association (CFTA) grades, U.S. Production: 2023: 70, 000, 000 - <85, 000 lb, 2022: 70, 2021: 70, 2020: 55, 000 - <70, This chemical is listed as a High Production Volume (HPV) (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and, or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B, 51FR21438)., (1971) 2.7X10+9 GRAMS (HEXADECYL ALCOHOLS), (1975) GREATER THAN 9.08X10+5 GRAMS, (1984) 2.48X10+11, ALCOHOLS C12 OR HIGHER, For more U.S. Production (Complete) data for 1-HEXADECANOL (10 total), U.S. Imports: (1972) 2.73X10+8 GRAMS (FATTY ALCOHOLS), (1975) 7.57X10+8 G (INCL OTHER FATTY ALCOHOLS), U.S. Exports: (1972) 1.22X10+9 GRAMS (7 FATTY ALCOHOLS), (1975) 2.24X10+9 G-9 CARBON ALCOHOLS & HIGHER, General Manufacturing Information: Soap, Cleaning Compound, and Toilet Preparation Manufacturing, Petroleum Lubricating Oil and Grease Manufacturing, Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing, Machinery Manufacturing, Other (requires additional information), All Other Basic Organic Chemical Manufacturing, Paint and Coating Manufacturing, 1-Hexadecanol: ACTIVE, Hexadecyl alcohol. ... Primary, branched chain, C16 alcohol, made up of an array of isomeric compounds maintained in constant proportion by a complex manufacturing process (not from spermaceti), Method of purification: crystallization, distillation., Reported uses: ice cream, ices ... 2.0 ppm, candy 2.0 ppm

Where it is used

Documented applications: Uses: CIR ingredient: Cetyl Alcohol, Used in cosmetics, pharmaceuticals, perfumes, and shampoos (emollient and emulsion modifier) and to make face creams, lotions, lipsticks, toilet preparations, and antiperspirant sticks, Also used as a coupling agent, foam stabilizer in detergents, base for making sulfonated fatty acids, monomer lubricant in suspension polymerization, and to retard evaporation of water when spread as a film on reservoirs or sprayed on growing plants, [HSDB], Dressing Hair [Category: Other], For Cetyl Alcohol (USEPA, OPP Pesticide Code: 001508) there are 0 labels match., SRP: Not registered for current use in the U.S., but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses., The active ingredient is no longer contained in any registered pesticide products ... "cancelled.", In cosmetics as emollient, emulsion modifier, coupling agent. Pharmaceutical aid (emulsifying and stiffening agent)., Perfumery, emulsifier, emollient, face creams, chemical intermediate, detergents, cosmetics, to retard evaporation of water when spread as a film on reservoirs or sprayed on growing plants, For more Uses (Complete) data for 1-HEXADECANOL (10 total), please visit the HSDB record page., Use Classification: Fragrance Ingredients, Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes, Flavoring Agents -> JECFA Flavorings Index, Plastics -> Polymer Type -> N.a., Cosmetics -> Opacifying, Emulsifying, Skin conditioning, Emollient, Viscosity controlling, Plastics -> Other stabilisers, Industry Uses: Stabilizing agent, Thickening agent, Not Known or Reasonably Ascertainable, Intermediate, Solvent, Other, Lubricating agent, Surfactant (surface active agent), Consumer Uses: Not Known or Reasonably Ascertainable, Opacifer, Household Products: Information on 1 consumer products that contain Hexadecanol in the following categories is provided:, • Personal Care, Information on 959 consumer products that contain Cetyl alcohol in the following categories is provided:, • Commercial, Institutional, • Inside the Home, • Pesticides, • Pet Care, Methods of Manufacturing: Catalytic hydrogenation of the triglycerides obtained from coconut oil or tallow, oxidation of a chain growth product of ethylene oligomerized on a triethylaluminum catalyst, Prepared from palmitoyl chloride plus sodium borohydride ... from methylthiopalmitate plus Raney nickel: Ruzicka, Prelog, US patent 2, 509, 171 (1950 to Ciba), from hexadecyl bromide: Levine, Clippinger, US 3, 018, 308 (1962 to California Res. Corp.)., By saponifying spermaceti with caustic alkali, reduction of palmitic acid, Formulations, Preparations: Grades: Technical, cosmetic, national formulary., A typical anionic and cationic based all purpose face, head and body lotion contains 1% cetyl alcohol, Present in a popular cosmetic cream at 3%, Present in a typical depilatory formula at 6.15 wt%, National Formulary, natural, synthetic grades, flaked form, Flake, Cosmetic Fragerances Toiletries Association (CFTA) grades, U.S. Production: 2023: 70, 000, 000 - <85, 000 lb, 2022: 70, 2021: 70, 2020: 55, 000 - <70, This chemical is listed as a High Production Volume (HPV) (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and, or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B, 51FR21438)., (1971) 2.7X10+9 GRAMS (HEXADECYL ALCOHOLS), (1975) GREATER THAN 9.08X10+5 GRAMS, (1984) 2.48X10+11, ALCOHOLS C12 OR HIGHER, For more U.S. Production (Complete) data for 1-HEXADECANOL (10 total), U.S. Imports: (1972) 2.73X10+8 GRAMS (FATTY ALCOHOLS), (1975) 7.57X10+8 G (INCL OTHER FATTY ALCOHOLS), U.S. Exports: (1972) 1.22X10+9 GRAMS (7 FATTY ALCOHOLS), (1975) 2.24X10+9 G-9 CARBON ALCOHOLS & HIGHER, General Manufacturing Information: Soap, Cleaning Compound, and Toilet Preparation Manufacturing, Petroleum Lubricating Oil and Grease Manufacturing, Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing, Machinery Manufacturing, Other (requires additional information), All Other Basic Organic Chemical Manufacturing, Paint and Coating Manufacturing, 1-Hexadecanol: ACTIVE, Hexadecyl alcohol. ... Primary, branched chain, C16 alcohol, made up of an array of isomeric compounds maintained in constant proportion by a complex manufacturing process (not from spermaceti), Method of purification: crystallization, distillation., Reported uses: ice cream, ices ... 2.0 ppm, candy 2.0 ppm.

Purchase Profile

What this product is

1-Hexadecanol is a chemical compound with CAS registry number 36653-82-4 and molecular formula C16H34O (molecular weight 242.26 g/mol).

Identification

CAS number: 36653-82-4

Its molecular formula C16H34O comprises 16 C, 34 H, 1 O atoms.

Also known as: 1-Hexadecanol · Cetyl Alcohol · C16 Alcohol

Frequently Asked Questions

What is the CAS number of 1-Hexadecanol?

The CAS registry number of 1-Hexadecanol is 36653-82-4.

What is the molecular formula and molecular weight of 1-Hexadecanol?

Molecular formula C16H34O, molecular weight 242.26 g/mol.

What other names is 1-Hexadecanol known by?

It is also registered under: 1-Hexadecanol, Cetyl Alcohol, C16 Alcohol.

What are the documented applications of 1-Hexadecanol?

Recorded applications: Uses: CIR ingredient: Cetyl Alcohol, Used in cosmetics, pharmaceuticals, perfumes, and shampoos (emollient and emulsion modifier) and to make face creams, lotions, lipsticks, toilet preparations, and antiperspirant sticks, Also used as a coupling agent, foam stabilizer in detergents, base for making sulfonated fatty acids, monomer lubricant in suspension polymerization, and to retard evaporation of water when spread as a film on reservoirs or sprayed on growing plants, [HSDB], Dressing Hair [Category: Other], For Cetyl Alcohol (USEPA, OPP Pesticide Code: 001508) there are 0 labels match., SRP: Not registered for current use in the U.S., but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses., The active ingredient is no longer contained in any registered pesticide products ... "cancelled.", In cosmetics as emollient, emulsion modifier, coupling agent. Pharmaceutical aid (emulsifying and stiffening agent)., Perfumery, emulsifier, emollient, face creams, chemical intermediate, detergents, cosmetics, to retard evaporation of water when spread as a film on reservoirs or sprayed on growing plants, For more Uses (Complete) data for 1-HEXADECANOL (10 total), please visit the HSDB record page., Use Classification: Fragrance Ingredients, Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes, Flavoring Agents -> JECFA Flavorings Index, Plastics -> Polymer Type -> N.a., Cosmetics -> Opacifying, Emulsifying, Skin conditioning, Emollient, Viscosity controlling, Plastics -> Other stabilisers, Industry Uses: Stabilizing agent, Thickening agent, Not Known or Reasonably Ascertainable, Intermediate, Solvent, Other, Lubricating agent, Surfactant (surface active agent), Consumer Uses: Not Known or Reasonably Ascertainable, Opacifer, Household Products: Information on 1 consumer products that contain Hexadecanol in the following categories is provided:, • Personal Care, Information on 959 consumer products that contain Cetyl alcohol in the following categories is provided:, • Commercial, Institutional, • Inside the Home, • Pesticides, • Pet Care, Methods of Manufacturing: Catalytic hydrogenation of the triglycerides obtained from coconut oil or tallow, oxidation of a chain growth product of ethylene oligomerized on a triethylaluminum catalyst, Prepared from palmitoyl chloride plus sodium borohydride ... from methylthiopalmitate plus Raney nickel: Ruzicka, Prelog, US patent 2, 509, 171 (1950 to Ciba), from hexadecyl bromide: Levine, Clippinger, US 3, 018, 308 (1962 to California Res. Corp.)., By saponifying spermaceti with caustic alkali, reduction of palmitic acid, Formulations, Preparations: Grades: Technical, cosmetic, national formulary., A typical anionic and cationic based all purpose face, head and body lotion contains 1% cetyl alcohol, Present in a popular cosmetic cream at 3%, Present in a typical depilatory formula at 6.15 wt%, National Formulary, natural, synthetic grades, flaked form, Flake, Cosmetic Fragerances Toiletries Association (CFTA) grades, U.S. Production: 2023: 70, 000, 000 - <85, 000 lb, 2022: 70, 2021: 70, 2020: 55, 000 - <70, This chemical is listed as a High Production Volume (HPV) (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and, or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B, 51FR21438)., (1971) 2.7X10+9 GRAMS (HEXADECYL ALCOHOLS), (1975) GREATER THAN 9.08X10+5 GRAMS, (1984) 2.48X10+11, ALCOHOLS C12 OR HIGHER, For more U.S. Production (Complete) data for 1-HEXADECANOL (10 total), U.S. Imports: (1972) 2.73X10+8 GRAMS (FATTY ALCOHOLS), (1975) 7.57X10+8 G (INCL OTHER FATTY ALCOHOLS), U.S. Exports: (1972) 1.22X10+9 GRAMS (7 FATTY ALCOHOLS), (1975) 2.24X10+9 G-9 CARBON ALCOHOLS & HIGHER, General Manufacturing Information: Soap, Cleaning Compound, and Toilet Preparation Manufacturing, Petroleum Lubricating Oil and Grease Manufacturing, Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing, Machinery Manufacturing, Other (requires additional information), All Other Basic Organic Chemical Manufacturing, Paint and Coating Manufacturing, 1-Hexadecanol: ACTIVE, Hexadecyl alcohol. ... Primary, branched chain, C16 alcohol, made up of an array of isomeric compounds maintained in constant proportion by a complex manufacturing process (not from spermaceti), Method of purification: crystallization, distillation., Reported uses: ice cream, ices ... 2.0 ppm, candy 2.0 ppm.

PubChem Public Data

Public-database records for 1-Hexadecanol (CAS 36653-82-4), reproduced here for independent cross-checking.

Safety classification and hazard statements

GHS notification summary70.6% (2392 / 3386)
Reported hazard statementsH319 (21.9%)

This chemical does not meet GHS hazard criteria for 70.6% (2392 of 3386) of all reports.

H319 (21.9%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

Regulatory listings

Regulatory & Food ContactEU Flavoring substances
FDA Substance added to food: FLAVORING AGENT OR ADJUVANT
FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS
Flavoring Agents
FLAVOURING_AGENT: Flavouring Agent
Flower, Wax
GHS notification summary70.6% (2392 / 3386)

Physical description and handling notes

  • Liquid; Wet Solid; Other Solid; Liquid; Dry Powder; Other Solid
  • White solid; [Hawley]
  • Solid
  • white solid/odourless
  • FLAKES FROM ETHYL ACETATE
  • SOLID OR LEAF-LIKE CRYSTALS

Reported physical properties

沸点344
沸点334 °C at 760 mm Hg
沸点344 °C
熔点49.3
熔点49.3 °C
熔点50 °C
闪点175 °C
溶解度In water, 4.1X10-2 mg/L at 25 °C
溶解度1.34e-05 mg/mL at 25 °C
密度0.8187 at 50 °C/4 °C

How this substance is indexed

CAS Registry Number36653-82-4
PubChem CID2682
分子式C16H34O
分子量242.26 g/mol
IUPAC 名称hexadecan-1-ol
InChIKeyBXWNKGSJHAJOGX-UHFFFAOYSA-N
UNII(FDA)936JST6JCN
ChEBI 编号CHEBI:16125
FEMA 编号2554
JECFA 编号114

Documented uses

  • Used in cosmetics, pharmaceuticals, perfumes, and shampoos (emollient and emulsion modifier) and to make face creams, lotions, lipsticks, toilet preparations, and antiperspirant sticks; Also used as a coupling agent, foam stabilizer in detergents, base for making sulfonated fatty acids, monomer lubricant in suspension polymerization, and to retard evaporation of water when spread as a film on reservoirs or sprayed on growing plants; [HSDB]
  • Dressing Hair [Category: Other]
  • In cosmetics as emollient, emulsion modifier, coupling agent. Pharmaceutical aid (emulsifying and stiffening agent).
  • Perfumery, emulsifier, emollient, foam stabilizer in detergents, face creams, lotions, lipsticks, toilet preparations, chemical intermediate, detergents, pharmaceuticals, cosmetics, base for making sulfonated fatty acids, to retard evaporation of water when spread as a film on reservoirs or sprayed on growing plants
  • For more Uses (Complete) data for 1-HEXADECANOL (10 total), please visit the HSDB record page.
  • Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes

Names this substance appears under

1-Hexadecanol; cetyl alcohol; Hexadecan-1-ol; 36653-82-4; Palmityl alcohol; Cetanol; Hexadecyl alcohol; Cetaffine; N-Hexadecanol; n-Cetyl alcohol; Cetylol; n-1-Hexadecanol; Cetal; Ethal; Ethol; Cetylic alcohol

Computed molecular descriptors

分子量242.44
XLogP37.3
氢键供体数1
氢键受体数1
可旋转键数14
精确质量242.260965704
单同位素质量242.260965704
拓扑极性表面积20.2
重原子数17
形式电荷0

Database abstract

1-Hexadecanol is identified by CAS 36653-82-4, molecular formula C16H34O and molecular weight 242.26 g/mol. UNII 936JST6JCN; ChEBI 16125; InChIKey BXWNKGSJHAJOGX-UHFFFAOYSA-N. 沸点: 344; 沸点: 334 °C at 760 mm Hg; 沸点: 344 °C.

Source: PubChem / Wikidata; the batch COA governs where values differ.

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