3,5-二羟基-3-甲基戊酸

Name: 3,5-二羟基-3-甲基戊酸
Brand: 济南圣和化工有限公司

CAS 150-97-0C6H12O4MW 148.16

3,5-二羟基-3-甲基戊酸，CAS 登记号 150-97-0，由济南圣和化工有限公司现货供应，可提供纯度按批次COA提供(不公开发布) 的规格，下游主要用于有机化学品。支持样品与小批量试用，批量价格请联系我们获取，验收以批次 COA 为准。

规格参数

CAS号150-97-0

分子式C6H12O4

分子量148.16

LogP-1

纯度按批次COA提供(不公开发布)

包装按订单/批次确认(不公开发布)

应用领域有机化学品

类别有机化学品

用途与场景

有机化学品

包装与供货

包装规格按订单/批次确认(不公开发布)

纯度规格按批次COA提供(不公开发布)

储存条件密封、阴凉干燥处保存

供货周期现货/按订单安排

文件与支持

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常见问题

在哪里能查到 3,5-二羟基-3-甲基戊酸的 CAS 号？

本页已列出 3,5-二羟基-3-甲基戊酸的 CAS 号：150-97-0，可与随货 COA 核对。

可以提供哪些规格和包装？

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3,5-二羟基-3-甲基戊酸一般用在什么产品里？

主要涉及有机化学品。

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PubChem 公开数据

Description

3,5-dihydroxy-3-methylvaleric acid · CAS 150-97-0 · C6H12O4. UNII S5UOB36OCZ.

Identification

CAS Registry Number	150-97-0
PubChem CID	449
Molecular formula	C6H12O4
IUPAC name	3,5-dihydroxy-3-methylpentanoic acid
UNII (FDA)	S5UOB36OCZ

Computed Descriptors

Molecular Weight	148.16
XLogP3	-1
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	4
Exact Mass	148.07355886
Monoisotopic Mass	148.07355886
Topological Polar Surface Area	77.8
Heavy Atom Count	10
Formal Charge	0

Physical description & handling notes

Oily liquid
Very soluble in water, but also soluble in organic solvents, especially polar organic solvents.
Crystals from benzene + petroleum ether, mp 96-97 °C. Specific optical rotation: -20 deg at 20 °C/D (c = 2 in ethanol) /Benzhydrylamide/
Hygroscopic crystals, mp 28 °C /delta-Lactone/

Documented Uses

... An inhibitor of cholesterol synthesis
The self-condensation of two molecules of acetyl coenzyme A (CoA) forms acetoacetyl CoA. Condensation of acetoacetyl CoA with a third molecule of acetyl CoA, then followed by an NADPH-mediated reduction of the thioester moiety produces mevalonic acid.
Precursor in the biosynthesis of cholesterol
/EXPL/ Twenty eight patients with heterozygous familial hypercholesterolemia were treated with mevalonic acid (an inhibitor of cholesterol synthesis) for 45 days. Patients received a daily dose of 750 to 1500 mg mevalonic acid depending on plasma cholesterol levels. Results showed a significant reduction in cholesterol values whereas no significant difference was observed in HDL cholesterol and triglyceride levels.
Mevalonic acid is an intermediate after the rate-limiting step in cholesterol biosynthesis, which is catalyzed by 3-hydroxy-3-methylglutaryl coenzyme A reductase.
The mevalonate pathway is an important metabolic pathway which plays a key role in multiple cellular processes by synthesizing sterol isoprenoids, such as cholesterol, and non-sterol isoprenoids, such as dolichol, heme-A, isopentenyl tRNA...

Synonyms

150-97-0; DL-Mevalonic acid; Hiochic acid; Pentanoic acid, 3,5-dihydroxy-3-methyl-; S5UOB36OCZ; Acid, Mevalonic; DTXSID5040546; CHEBI:25351; RefChem:818790; DTXCID10209648; 3,5-Dihydroxy-3-methylvaleric acid; Mevalonic Acid; 3,5-dihydroxy-3-methylpentanoic acid; (RS)-mevalonate; 3,5-Dihydroxy-3-methyl-pentanoic acid; (RS)-MEVALONIC ACID

Frequently Asked Questions

What are the CAS number and molecular formula of 3,5-dihydroxy-3-methylvaleric acid?

CAS 150-97-0; molecular formula C6H12O4; molecular weight — g/mol.

What other names is 3,5-dihydroxy-3-methylvaleric acid known by?

150-97-0, DL-Mevalonic acid, Hiochic acid, Pentanoic acid, 3,5-dihydroxy-3-methyl-, S5UOB36OCZ, Acid, Mevalonic.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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