6-氨基己酸

Description

6-Aminocaproic acid · CAS 60-32-2 · C6H13NO2. UNII U6F3787206. Melting Point: 205; Melting Point: 202-203 °C; Melting Point: 205 °C.

Identification

CAS Registry Number	60-32-2
PubChem CID	564
Molecular formula	C6H13NO2
IUPAC name	6-aminohexanoic acid
UNII (FDA)	U6F3787206

Computed Descriptors

Molecular Weight	131.17
XLogP3	-3
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	5
Exact Mass	131.094628657
Monoisotopic Mass	131.094628657
Topological Polar Surface Area	63.3
Heavy Atom Count	9
Formal Charge	0

Physical & Chemical Properties

Melting Point	205
Melting Point	202-203 °C
Melting Point	205 °C
Solubility	505000
Solubility	505.0 mg/mL at 25 °C
LogP	-2.95
Ionization Efficiency	2.9
Ionization Efficiency	2.7
Ionization Efficiency	MeCN (80%)
Ionization Efficiency	DOI:10.1038/s41598-020-62573-z

Physical description & handling notes

• Wet Solid
• White solid; [HSDB] White crystalline solid; [MSDSonline]
• Solid
• FINE, WHITE, CRYSTALLINE POWDER
• LEAVES FROM ETHER
• ODORLESS, OR NEARLY SO

Regulatory Status

GHS notification summary	78.6% (206 / 262)

GHS Hazard Classification

GHS notification summary	78.6% (206 / 262)
Reported hazard statements	H315 (20.6%), H319 (21%), H335 (20.6%)

Documented Uses

• Used as a captive chemical intermediate in the production of nylon 6; [HSDB] Used as a hemostatic; [Merck Index] An inhibitor of fibrinolysis and sold as Amicar; [REPROTOX]
• ANTIDOTE FOR OVERDOSAGE IN FIBRINOLYTIC THERAPY; CAPTIVE CHEM INT IN PRODUCTION OF NYLON 6
• Pharmaceuticals -> Animal Drugs -> Approved in Taiwan
• HEATING OF AN AQUEOUS SOLUTION OF CAPROLACTAM WITH CALCIUM HYDROXIDE TO GIVE CALCIUM AMINOCAPROATE, FOLLOWED BY REACTION WITH SULFURIC ACID
• ...FROM EPSILON-BENZOYLAMINOCAPRONITRILE: RUZICKA, HUGOSON, HELV CHIM ACTA 4, 472 (1921); FROM EPSILON CAPROLACTAM...SULZBACHER, MFR CHEMIST 33, 463 (1963); FROM 1-HYDROXYCYCLOHEXYLHYDROPEROXIDE: MINISCI, PORTOLANI; GAZZ CHIM ITAL 89, 1941 (1959).
• EXCLUDING CAPTIVE USE IN NYLON 6 PRODUCTION FROM CAPROLACTAM, PROBABLY 100% IS USED AS A FIBRINOLYTIC INHIBITOR (1976)

Synonyms

6-aminohexanoic acid; 6-Aminocaproic acid; aminocaproic acid; 60-32-2; Hexanoic acid, 6-amino-; Acepramine; Epsicapron; Epsilcapramin; Capramol; Caprolisin; Acepramin; Hemopar; Ipsilon; Respramin; Amikar; EACA

Frequently Asked Questions

What are the CAS number and molecular formula of 6-Aminocaproic acid?

CAS 60-32-2; molecular formula C6H13NO2; molecular weight — g/mol.

What other names is 6-Aminocaproic acid known by?

6-aminohexanoic acid, 6-Aminocaproic acid, aminocaproic acid, 60-32-2, Hexanoic acid, 6-amino-, Acepramine.

Is 6-Aminocaproic acid classified as hazardous?

78.6% of GHS notifications report no hazard classification (206 of 262).

What are the key physical properties of 6-Aminocaproic acid?

Melting Point: 205; Melting Point: 202-203 °C; Melting Point: 205 °C; Solubility: 505000.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.