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Bendamustine Hydrochloride

CAS 3543-75-7C16H22Cl3N3O2MW 394.7

Bendamustine Hydrochloride (CAS No. 3543-75-7) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Pharmaceutical Intermediates & APIs. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Specifications

CAS Number3543-75-7
Molecular FormulaC16H22Cl3N3O2
Molecular Weight394.7
Purity按批次COA提供(不公开发布)
Packaging按订单/批次确认(不公开发布)
ApplicationsPharmaceutical Intermediates & APIs
CategoryPharmaceutical Intermediates & APIs

Where it is used

Pharmaceutical Intermediates & APIs

Packaging & Supply

Packaging按订单/批次确认(不公开发布)
Purity按批次COA提供(不公开发布)
StorageSealed, cool and dry place
Lead TimeIn stock / per order

Documents & Support

COA provided with every batch; MSDS and technical documents available on request. Email us with product name and CAS number for a quote within one business day.

Frequently Asked Questions

What is the CAS number of Bendamustine Hydrochloride?

The CAS number of Bendamustine Hydrochloride is 3543-75-7.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of Bendamustine Hydrochloride?

Main applications include Pharmaceutical Intermediates & APIs.

How do I buy Bendamustine Hydrochloride or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

Bendamustine Hydrochloride · CAS 3543-75-7 · C16H22Cl3N3O2. UNII 981Y8SX18M.

Identification

CAS Registry Number3543-75-7
PubChem CID77082
Molecular formulaC16H22Cl3N3O2
IUPAC name4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid;hydrochloride
UNII (FDA)981Y8SX18M

Computed Descriptors

Molecular Weight394.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count9
Exact Mass393.077760
Monoisotopic Mass393.077760
Topological Polar Surface Area58.4
Heavy Atom Count24
Formal Charge0
Complexity380

GHS Hazard Classification

Reported hazard statementsH301 (95.9%), H340 (12.2%), H350 (12.2%), H351 (87.8%), H360 (95.9%)

H301 (95.9%): Toxic if swallowed [Danger Acute toxicity, oral]

H340 (12.2%): May cause genetic defects [Danger Germ cell mutagenicity]

Documented Uses

  • Breast Feeding; Lactation; Antineoplastic Agents, Alkylating; Nitrosourea Compounds
  • Bendamustine hydrochloride is approved to treat:
  • • B-cell non-Hodgkin lymphoma (NHL) that is indolent (slow-growing) and got worse during or within 6 months after treatment with rituximab.
  • • Chronic lymphocytic leukemia (CLL).
  • Bendamustine hydrochloride is also being studied in the treatment of other types of cancer.
  • A class of drugs that differs from other alkylating agents used clinically in that they are monofunctional and thus unable to cross-link cellular macromolecules. Among their common properties are a requirement for metabolic activation to intermediates with antitumor efficacy and the presence in their chemical structures of N-methyl groups, that after metabolism, can covalently modify cellular DNA. The precise mechanisms by which each of these drugs acts to kill tumor cells are not completely understood. (From AMA,

Synonyms

Bendamustine hydrochloride; 3543-75-7; Bendamustine HCl; Treanda; Ribomustin; Bendamustin hydrochloride; Bendeka; Ribomustine; SyB L-0501; VIVIMUSTA; Levact; NSC-138783; SYBL-0501; 981Y8SX18M; DTXSID40188912; NSC138783

Frequently Asked Questions

What are the CAS number and molecular formula of Bendamustine Hydrochloride?

CAS 3543-75-7; molecular formula C16H22Cl3N3O2; molecular weight — g/mol.

What other names is Bendamustine Hydrochloride known by?

Bendamustine hydrochloride, 3543-75-7, Bendamustine HCl, Treanda, Ribomustin, Bendamustin hydrochloride.

Is Bendamustine Hydrochloride classified as hazardous?

Hazard statements reported: H301, H340, H350, H351, H360.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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