Cabergoline

Description

Cabergoline · CAS 81409-90-7 · C26H37N5O2. UNII LL60K9J05T. Melting Point: 102-104 °C; Melting Point: 102 - 104 °C; Solubility: 6.40e-02 g/L.

Identification

CAS Registry Number	81409-90-7
PubChem CID	54746
Molecular formula	C26H37N5O2
IUPAC name	(6aR,9R,10aR)-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)-7-prop-2-enyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide
UNII (FDA)	LL60K9J05T

Computed Descriptors

Molecular Weight	451.6
XLogP3	3.4
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	8
Exact Mass	451.29472544
Monoisotopic Mass	451.29472544
Topological Polar Surface Area	71.7
Heavy Atom Count	33
Formal Charge	0

Physical & Chemical Properties

Melting Point	102-104 °C
Melting Point	102 - 104 °C
Solubility	6.40e-02 g/L
LogP	2.6

Physical description & handling notes

• Solid
• Insoluble

GHS Hazard Classification

Reported hazard statements	H302 (97.8%), H315 (84.8%), H319 (82.6%), H335 (82.6%)

Documented Uses

• Use (kg; approx.) in Germany (2009): >10
• Consumption (g per capita; approx.) in Germany (2009): 0.000122
• For the treatment of hyperprolactinemic disorders, either idiopathic or due to prolactinoma (prolactin-secreting adenomas). May also be used to manage symptoms of Parkinsonian Syndrome as monotherapy during initial symptomatic management or as an adjunct to levodopa therapy during advanced stages of disease.
• Breast Feeding; Lactation; Milk, Human; Antiparkinson Agents; Dopamine Agonists
• Medicines for disorders of the pituitary hormone system
• Oral - Solid - tablet: 0.5 mg; 1 mg

Synonyms

cabergoline; 81409-90-7; Dostinex; Cabaser; Cabergolina; Cabergolinum; FCE-21336; Velactis; FCE 21336; DTXSID6022719; LL60K9J05T; 1-((6-Allylergolin-8beta-yl)carbonyl)-1-(3-(dimethylamino)propyl)-3-ethylurea; CHEBI:3286; DTXCID502719; 1-ethyl-3-(3'-dimethylamionpropyl)-2-(6'-allylergoline-8'beta-carbonyl)urea; 1-[(6-allylergoline-8beta-yl)carbonyl]-1-[3-(dimethylamino)propyl]-3-ethylurea

Frequently Asked Questions

What are the CAS number and molecular formula of Cabergoline?

CAS 81409-90-7; molecular formula C26H37N5O2; molecular weight — g/mol.

What other names is Cabergoline known by?

cabergoline, 81409-90-7, Dostinex, Cabaser, Cabergolina, Cabergolinum.

Is Cabergoline classified as hazardous?

Hazard statements reported: H302, H315, H319, H335.

What are the key physical properties of Cabergoline?

Melting Point: 102-104 °C; Melting Point: 102 - 104 °C; Solubility: 6.40e-02 g/L; LogP: 2.6.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.