Carboxin

Description

Carboxin · CAS 5234-68-4 · C12H13NO2S. UNII 5A8K850HDE. Melting Point: 91.5; Flash Point: 203 °C; Solubility: 147.

Identification

CAS Registry Number	5234-68-4
PubChem CID	21307
Molecular formula	C12H13NO2S
IUPAC name	6-methyl-N-phenyl-2,3-dihydro-1,4-oxathiine-5-carboxamide
UNII (FDA)	5A8K850HDE

Computed Descriptors

Molecular Weight	235.30
XLogP3	2.1
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	2
Exact Mass	235.06669983
Monoisotopic Mass	235.06669983
Topological Polar Surface Area	63.6
Heavy Atom Count	16
Formal Charge	0

Physical & Chemical Properties

Melting Point	91.5
Flash Point	203 °C
Solubility	147
Solubility	In water, 147 mg/L at 20 °C
Density	1.7 g/mL
Vapor Pressure	0.00000018 [mmHg]
Vapor Pressure	1.5X10-7 mm Hg at 25 °C
LogP	2.14
LogP	log Kow = 2.3
LogP	1.73

Physical description & handling notes

• Carboxin appears as off-white crystals. Systemic fungicide and seed protectant.
• Colorless to off-white or white solid; [HSDB]
• CRYSTALS FROM ETHANOL OR METHANOL
• WHITE SOLID
• Off-white crystalline solid
• 91.5 to 92.5 °C and 98 to 101 °C, reflecting two crystalline structures which revert to one in solution.

Regulatory Status

GHS notification summary	1% (1 / 104)

GHS Hazard Classification

GHS notification summary	1% (1 / 104)
Reported hazard statements	H317, H373, H400, H410, H302 (42.3%)

Documented Uses

• Used as a systemic fungicide; for seed treatment for control of smuts and bunts on barley, wheat, and oats; for seedling diseases (particularly Rhizoctonia spp.) of barley, wheat, oats, rice, cotton, peanuts, soya beans, vegetables, maize, sorghum, and other crops; [HSDB] Applied to seeds before planting by seed treaters and farmworkers; No registered residential uses; [EPA REDs Fact Sheets]
• Systemic fungicide. /Used for/ seed treatment for control of smuts and bunts (particularly loose smut, Ustilago spp.), at 50-200 g/100 kg seed, on barley, wheat, and oats; seedling diseases (particularly Rhizoctonia spp.) of barley, wheat, oats, rice, cotton, peanuts, soya beans, vegetables, maize, sorghum, and other crops. The dimorphic forms do not differ in fungicidal activity.
• Effective systemic fungicide that controls by seed treatment basidomycete type of fungi such as smuts of small grains & Rhizoctonia solani of ... sugar beets ... It is particularly effective in control of loose smut of small grains caused by ustilago species.
• Seed treatment controls on smuts on barley, oats, wheat, and seedling diseases, such as Rhizoctonia solani, on barley, corn, cotton, oats, peanuts, rapeseed, rice sorghum, soybeans, wheat and other crops.
• Carboxin is produced by reaction of 2-chloro-3-oxobutyricanilide with 2-mercaptoethanol, followed by acid-catalyzed ring closure with elimination of water.
• By the reaction of alpha-chloroacetoacetanilide and 2-mercaptoethanol followed by acid catalyzed cyclization-dehydration.

Synonyms

CARBOXIN; 5234-68-4; Carboxine; Carbathiin; Vitavax; 2-Methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide; Oxatin; DCMO; Kisvax; Vitavax 75W; DMOC; Vitavax 100; Vitavax 735D; Kemikar; Vitaflo 250; Murganic

Frequently Asked Questions

What are the CAS number and molecular formula of Carboxin?

CAS 5234-68-4; molecular formula C12H13NO2S; molecular weight — g/mol.

What other names is Carboxin known by?

CARBOXIN, 5234-68-4, Carboxine, Carbathiin, Vitavax, 2-Methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide.

Is Carboxin classified as hazardous?

1% of GHS notifications report no hazard classification (1 of 104).

What are the key physical properties of Carboxin?

Melting Point: 91.5; Flash Point: 203 °C; Solubility: 147; Solubility: In water, 147 mg/L at 20 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.