胆碱，琥珀酸 (2:1)（酯）

Description

Choline,succinate (2:1) (ester) · CAS 306-40-1 · C14H30N2O4+2. UNII J2R869A8YF. Solubility: 7.57e-04 g/L.

Identification

CAS Registry Number	306-40-1
PubChem CID	5314
Molecular formula	C14H30N2O4+2
IUPAC name	trimethyl-[2-[4-oxo-4-[2-(trimethylazaniumyl)ethoxy]butanoyl]oxyethyl]azanium
UNII (FDA)	J2R869A8YF

Computed Descriptors

Molecular Weight	290.40
XLogP3	0.6
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	11
Exact Mass	290.22055744
Monoisotopic Mass	290.22055744
Topological Polar Surface Area	52.6
Heavy Atom Count	20
Formal Charge	2

Physical & Chemical Properties

Solubility	7.57e-04 g/L

Physical description & handling notes

• Solid
• Very soluble
• ODORLESS; DIHYDRATE IS HYGROSCOPIC; WHITE CRYSTALLINE POWDER; 1 G SOL IN ABOUT 1 ML H2O & ABOUT 350 ML ALC /CHLORIDE/
• Slightly hygroscopic crystals, mp 225 °C. Freely sol in water or normal saline, giving solns which are very slightly acidic. /Bromide/
• Exists as a dihydrate at room temperature, crystals, mp 156-163 °C. Anhydrous form mp approximately 190 °C. Slightly bitter taste. Freely soluble in water (about 1 g/1 ml water). Solubility in 95% ethanol: 0.42 g/ 100 ml. Sparingly soluble in benzene, chloroform. Practically insoluble in ether. The pH of a 2-5% aqueous solution may vary from 4.5 to 3.0. /Chloride/
• SLIGHTLY HYGROSCOPIC ... AQ SOLN UNDERGO PROGRESSIVE HYDROLYSIS WITH CORRESPONDING LOSS OF ACTIVITY & INCR IN ACIDITY. /BROMIDE/

Documented Uses

• Use (kg; approx.) in Germany (2009): >100
• Consumption (g per capita; approx.) in Germany (2009): 0.00122
• ... By reacting beta-bromoethyl succinate with trimethylamine. /Bromide/
• Prepd by reacting beta-bromoethyl succinate with trimethylamine. /Iodide/
• Succinic acid chloride may be coupled with choline chloride directly or with dimethylaminoethanol, followed by quarternization with methyl iodide. /Iodide/
• A third method is to start with the diethyl ester of succinic acid, then bring about the exchange reaction with dimethylaminoethanol, and quaternize with methyl iodide. /Iodide/

Synonyms

succinylcholine; Suxamethonium; Succinyldicholine; Succinocholine; Succinylbischoline; Succinoylcholine; Dicholine succinate; Diacetylcholine; 306-40-1; Ditiline; Choline, succinyl-; Suxamethonium ion; Succinylcholine ion; Suxamethonium cation; Succinic acid, diester with choline; Succinylcholine cation

Frequently Asked Questions

What are the CAS number and molecular formula of Choline,succinate (2:1) (ester)?

CAS 306-40-1; molecular formula C14H30N2O4+2; molecular weight — g/mol.

What other names is Choline,succinate (2:1) (ester) known by?

succinylcholine, Suxamethonium, Succinyldicholine, Succinocholine, Succinylbischoline, Succinoylcholine.

What are the key physical properties of Choline,succinate (2:1) (ester)?

Solubility: 7.57e-04 g/L.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.