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Oxaprozin

CAS 21256-18-8C18H15NO3MW 293.3

Oxaprozin (CAS No. 21256-18-8) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Pharmaceutical Intermediates & APIs. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Specifications

CAS Number21256-18-8
Molecular FormulaC18H15NO3
Molecular Weight293.3
Melting Point158-159 °C
LogP4.19
Purity按批次COA提供(不公开发布)
Packaging按订单/批次确认(不公开发布)
ApplicationsPharmaceutical Intermediates & APIs
CategoryPharmaceutical Intermediates & APIs

Where it is used

Pharmaceutical Intermediates & APIs

Packaging & Supply

Packaging按订单/批次确认(不公开发布)
Purity按批次COA提供(不公开发布)
StorageSealed, cool and dry place
Lead TimeIn stock / per order

Documents & Support

COA provided with every batch; MSDS and technical documents available on request. Email us with product name and CAS number for a quote within one business day.

Frequently Asked Questions

What is the CAS number of Oxaprozin?

The CAS number of Oxaprozin is 21256-18-8.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of Oxaprozin?

Main applications include Pharmaceutical Intermediates & APIs.

How do I buy Oxaprozin or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

Oxaprozin · CAS 21256-18-8 · C18H15NO3. UNII MHJ80W9LRB. Melting Point: 158-159 °C; Melting Point: 160.5 to 161.5 °C; Melting Point: 158 - 159 °C.

Identification

CAS Registry Number21256-18-8
PubChem CID4614
Molecular formulaC18H15NO3
IUPAC name3-(4,5-diphenyl-1,3-oxazol-2-yl)propanoic acid
UNII (FDA)MHJ80W9LRB

Computed Descriptors

Molecular Weight293.3
XLogP34.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count5
Exact Mass293.10519334
Monoisotopic Mass293.10519334
Topological Polar Surface Area63.3
Heavy Atom Count22
Formal Charge0

Physical & Chemical Properties

Melting Point158-159 °C
Melting Point160.5 to 161.5 °C
Melting Point158 - 159 °C
Solubility3.25e-02 g/L
LogP4.19
LogPlog Kow = 4.19
LogP3.7
LogP2.82
Dissociation Constants4.3
Dissociation ConstantspKa = 4.3

Physical description & handling notes

  • Solid
  • Crystals from methanol
  • Insoluble
  • Slightly soluble in alcohol. Insoluble in water
  • When heated to decomposition it emits toxic fumes of /Nitrogen oxide/.
  • 169.7 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

GHS Hazard Classification

Reported hazard statementsH302 (25%), H315 (25%), H319 (25%), H411 (25%), H412 (25%), H413 (25%)

H302 (25%): Harmful if swallowed [Warning Acute toxicity, oral]

H315 (25%): Causes skin irritation [Warning Skin corrosion/irritation]

Documented Uses

  • Therapeutic Category: Anti-inflammatory
  • Consumption (g per capita) in the USA (2002): 0.067
  • Preparation: FR 2001036 (1969 Inst Farm Serano); ... K. Brown GB 1206403 and US 3578671 (1970, 1971 to Wyeth)
  • Used to relieve the inflammation, swelling, stiffness, and joint pain associated with rheumatoid arthritis and osteoarthritis.
  • Oxaprozin is a long acting nonsteroidal antiinflammatory drug (NSAID) available by prescription only which is used for therapy of chronic arthritis. Oxaprozin has been linked to rare instances of idiosyncratic drug induced liver disease.
  • Breast Feeding; Lactation; Milk, Human; Analgesic Agents; Anti-inflammatory Agents, Nonsteroidal

Synonyms

oxaprozin; 21256-18-8; Daypro; 3-(4,5-Diphenyloxazol-2-yl)propanoic acid; Alvo; Oxaprozine; Oxaprozinum; Deflam; Oxaprozina; 4,5-Diphenyl-2-oxazolepropanoic acid; 4,5-Diphenyl-2-oxazolepropionic acid; WY-21743; WY-21,743; 2-Oxazolepropanoic acid, 4,5-diphenyl-; Duraprox; DTXSID1045118

Frequently Asked Questions

What are the CAS number and molecular formula of Oxaprozin?

CAS 21256-18-8; molecular formula C18H15NO3; molecular weight — g/mol.

What other names is Oxaprozin known by?

oxaprozin, 21256-18-8, Daypro, 3-(4,5-Diphenyloxazol-2-yl)propanoic acid, Alvo, Oxaprozine.

Is Oxaprozin classified as hazardous?

Hazard statements reported: H302, H315, H319, H411, H412.

What are the key physical properties of Oxaprozin?

Melting Point: 158-159 °C; Melting Point: 160.5 to 161.5 °C; Melting Point: 158 - 159 °C; Solubility: 3.25e-02 g/L.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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