奥沙普嗪

Name: 奥沙普嗪
Brand: 济南圣和化工有限公司

CAS 21256-18-8C18H15NO3MW 293.3

奥沙普嗪，CAS 登记号 21256-18-8，由济南圣和化工有限公司现货供应，可提供纯度按批次COA提供(不公开发布) 的规格，下游主要用于医药中间体及原料药。支持样品与小批量试用，批量价格请联系我们获取，验收以批次 COA 为准。

规格参数

CAS号21256-18-8

分子式C18H15NO3

分子量293.3

熔点158-159 °C

LogP4.19

纯度按批次COA提供(不公开发布)

包装按订单/批次确认(不公开发布)

应用领域医药中间体及原料药

类别医药中间体及原料药

用途与场景

医药中间体及原料药

包装与供货

包装规格按订单/批次确认(不公开发布)

纯度规格按批次COA提供(不公开发布)

储存条件密封、阴凉干燥处保存

供货周期现货/按订单安排

文件与支持

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常见问题

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本页已列出奥沙普嗪的 CAS 号：21256-18-8，可与随货 COA 核对。

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奥沙普嗪一般用在什么产品里？

主要涉及医药中间体及原料药。

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PubChem 公开数据

Description

Oxaprozin · CAS 21256-18-8 · C18H15NO3. UNII MHJ80W9LRB. Melting Point: 158-159 °C; Melting Point: 160.5 to 161.5 °C; Melting Point: 158 - 159 °C.

Identification

CAS Registry Number	21256-18-8
PubChem CID	4614
Molecular formula	C18H15NO3
IUPAC name	3-(4,5-diphenyl-1,3-oxazol-2-yl)propanoic acid
UNII (FDA)	MHJ80W9LRB

Computed Descriptors

Molecular Weight	293.3
XLogP3	4.2
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	5
Exact Mass	293.10519334
Monoisotopic Mass	293.10519334
Topological Polar Surface Area	63.3
Heavy Atom Count	22
Formal Charge	0

Physical & Chemical Properties

Melting Point	158-159 °C
Melting Point	160.5 to 161.5 °C
Melting Point	158 - 159 °C
Solubility	3.25e-02 g/L
LogP	4.19
LogP	log Kow = 4.19
LogP	3.7
LogP	2.82
Dissociation Constants	4.3
Dissociation Constants	pKa = 4.3

Physical description & handling notes

Solid
Crystals from methanol
Insoluble
Slightly soluble in alcohol. Insoluble in water
When heated to decomposition it emits toxic fumes of /Nitrogen oxide/.
169.7 Å² [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

GHS Hazard Classification

Reported hazard statements	H302 (25%), H315 (25%), H319 (25%), H411 (25%), H412 (25%), H413 (25%)

H302 (25%): Harmful if swallowed [Warning Acute toxicity, oral]

H315 (25%): Causes skin irritation [Warning Skin corrosion/irritation]

Documented Uses

Therapeutic Category: Anti-inflammatory
Consumption (g per capita) in the USA (2002): 0.067
Preparation: FR 2001036 (1969 Inst Farm Serano); ... K. Brown GB 1206403 and US 3578671 (1970, 1971 to Wyeth)
Used to relieve the inflammation, swelling, stiffness, and joint pain associated with rheumatoid arthritis and osteoarthritis.
Oxaprozin is a long acting nonsteroidal antiinflammatory drug (NSAID) available by prescription only which is used for therapy of chronic arthritis. Oxaprozin has been linked to rare instances of idiosyncratic drug induced liver disease.
Breast Feeding; Lactation; Milk, Human; Analgesic Agents; Anti-inflammatory Agents, Nonsteroidal

Synonyms

oxaprozin; 21256-18-8; Daypro; 3-(4,5-Diphenyloxazol-2-yl)propanoic acid; Alvo; Oxaprozine; Oxaprozinum; Deflam; Oxaprozina; 4,5-Diphenyl-2-oxazolepropanoic acid; 4,5-Diphenyl-2-oxazolepropionic acid; WY-21743; WY-21,743; 2-Oxazolepropanoic acid, 4,5-diphenyl-; Duraprox; DTXSID1045118

Frequently Asked Questions

What are the CAS number and molecular formula of Oxaprozin?

CAS 21256-18-8; molecular formula C18H15NO3; molecular weight — g/mol.

What other names is Oxaprozin known by?

oxaprozin, 21256-18-8, Daypro, 3-(4,5-Diphenyloxazol-2-yl)propanoic acid, Alvo, Oxaprozine.

Is Oxaprozin classified as hazardous?

Hazard statements reported: H302, H315, H319, H411, H412.

What are the key physical properties of Oxaprozin?

Melting Point: 158-159 °C; Melting Point: 160.5 to 161.5 °C; Melting Point: 158 - 159 °C; Solubility: 3.25e-02 g/L.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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