盐酸普萘洛尔

Description

Propranolol HCl · CAS 318-98-9 · C16H21NO2.ClH. UNII F8A3652H1V. Melting Point: 163-164 °C; Dissociation Constants: pKa = 9.45.

Identification

CAS Registry Number	318-98-9
PubChem CID	62882
Molecular formula	C16H21NO2.ClH
IUPAC name	1-naphthalen-1-yloxy-3-(propan-2-ylamino)propan-2-ol;hydrochloride
UNII (FDA)	F8A3652H1V

Computed Descriptors

Molecular Weight	295.80
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	6
Exact Mass	295.1339066
Monoisotopic Mass	295.1339066
Topological Polar Surface Area	41.5
Heavy Atom Count	20
Formal Charge	0
Complexity	257

Physical & Chemical Properties

Melting Point	163-164 °C
Dissociation Constants	pKa = 9.45

Physical description & handling notes

• White or almost white powder
• Solid
• Crystals from n-propanol
• Odorless
• Bitter
• Practically insoluble in ether, benzene, ethyl acetate

GHS Hazard Classification

Reported hazard statements	H302 (98.7%), H312 (95.7%), H317 (95.7%), H332 (95.7%)

Documented Uses

• Breast Feeding; Lactation; Milk, Human; Antihypertensive Agents; Adrenergic Beta-Antagonists; Antiarrhythmics
• Hemangeol (Propranolol Hydrochloride)
• Propranolol hydrochloride is approved to treat:
• • Infantile hemangioma (a benign tumor). It is used in infants 5 weeks to 5 months of age. This use is approved for the Hemangeol brand of propranolol hydrochloride.
• Propranolol hydrochloride is also used under other brand names to treat hypertension, including before surgery for patients with pheochromocytoma, and other diseases and conditions. It is also being studied in the treatment of other conditions and types of cancer.
• Adrenergic beta-Antagonists; Anti-Anxiety Agents; Anti-Arrhythmia Agents; Antihypertensive Agents; Sympatholytics; Vasodilator Agents

Synonyms

Propranolol hydrochloride; 318-98-9; Propranolol Hcl; Avlocardyl; Dociton; Anaprilin; Caridolol; Inderalici; Apsolol; Beprane; Berkolol; Deralin; Indobloc; Obsidan; Pylapron; Sloprolol

Frequently Asked Questions

What are the CAS number and molecular formula of Propranolol HCl?

CAS 318-98-9; molecular formula C16H21NO2.ClH; molecular weight — g/mol.

What other names is Propranolol HCl known by?

Propranolol hydrochloride, 318-98-9, Propranolol Hcl, Avlocardyl, Dociton, Anaprilin.

Is Propranolol HCl classified as hazardous?

Hazard statements reported: H302, H312, H317, H332.

What are the key physical properties of Propranolol HCl?

Melting Point: 163-164 °C; Dissociation Constants: pKa = 9.45.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.