熊果酸

Description

Ursolic acid · CAS 77-52-1 · C30H48O3. UNII P3M2575F3F. Melting Point: 284 °C.

Identification

CAS Registry Number	77-52-1
PubChem CID	64945
Molecular formula	C30H48O3
IUPAC name	(1S,2R,4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid
UNII (FDA)	P3M2575F3F

Computed Descriptors

Molecular Weight	456.7
XLogP3	7.3
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	1
Exact Mass	456.36034539
Monoisotopic Mass	456.36034539
Topological Polar Surface Area	57.5
Heavy Atom Count	33
Formal Charge	0

Physical & Chemical Properties

Melting Point	284 °C

Physical description & handling notes

• Solid
• Platelets from alcohol
• Large, lustrous prisms from absolute alcohol, fine hair-like needles from dilute alcohol
• MP: 246-247 °C /Ursolic acid methyl ester acetate/
• One part dissolves in 88 parts methanol, 178 alcohol, (35 boiling alcohol), 140 ether, 388 chloroform, 1675 carbon disulfide. Moderately soluble in acetone. Soluble in hot glacial acetic acid and in 2% alcoholic NaOH. Insoluble in petroleum ether.
• Specific optical rotation: +67.5 deg at 21 °C/D ( c = 1 in N alcohol KOH)

Regulatory Status

GHS notification summary	98.9% (92 / 93)

GHS Hazard Classification

GHS notification summary	98.9% (92 / 93)

Documented Uses

• ... Pharmacological activities including anti-inflammatory effects ...
• As emulsifying agent in pharmaceuticals, foods /Methyl ester acetate/
• Cosmetics product ingredient: Urs-12-en-28-oic acid, 3-hydroxy-, (3beta)- (Ursolic Acid)
• Urs-12-en-28-oic acid, 3-hydroxy-, (3.beta.)-: ACTIVE
• Both oleanolic acid and ursolic acid are effective in protecting against chemically induced liver injury in laboratory animals. Oleanolic acid has been marketed in China as an oral drug for human liver disorders.
• Substances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection.

Synonyms

Ursolic acid; Prunol; 77-52-1; Malol; Urson; Micromerol; (+)-Ursolic acid; NSC-4060; NSC-167406; CHEBI:9908; P3M2575F3F; Urs-12-en-28-oic acid, 3beta-hydroxy-; DTXSID70883221; Oleanolate, Sodium; 3 Epiursolic Acid; 3beta-ursolic acid

Frequently Asked Questions

What are the CAS number and molecular formula of Ursolic acid?

CAS 77-52-1; molecular formula C30H48O3; molecular weight — g/mol.

What other names is Ursolic acid known by?

Ursolic acid, Prunol, 77-52-1, Malol, Urson, Micromerol.

Is Ursolic acid classified as hazardous?

98.9% of GHS notifications report no hazard classification (92 of 93).

What are the key physical properties of Ursolic acid?

Melting Point: 284 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.