维生素 D2，1a-羟基-

Description

Vitamin D2, 1a-Hydroxy- · CAS 54573-75-0 · C28H44O2. UNII 3DIZ9LF5Y9.

Identification

CAS Registry Number	54573-75-0
PubChem CID	5281107
Molecular formula	C28H44O2
IUPAC name	trans-(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(E,2R,5R)-5,6-dimethylhept-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol
UNII (FDA)	3DIZ9LF5Y9

Computed Descriptors

Molecular Weight	412.6
XLogP3	6.3
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	5
Exact Mass	412.334130642
Monoisotopic Mass	412.334130642
Topological Polar Surface Area	40.5
Heavy Atom Count	30
Formal Charge	0

Physical description & handling notes

• Relatively insoluble

GHS Hazard Classification

Reported hazard statements	H300 (100%)

Documented Uses

• Doxercalciferol is indicated for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease on dialysis, as well as for the treatment of secondary hyperparathyroidism in patients with Stage 3 or Stage 4 chronic kidney disease.
• Avoid antacids. Specifically, avoid magnesium-containing antacids as co-administration with doxercalciferol increases the risk of hypermagnesemia.
• Organic substances that are required in small amounts for maintenance and growth, but which cannot be manufactured by the human body.
• Agents that inhibit BONE RESORPTION and/or favor BONE MINERALIZATION and BONE REGENERATION. They are used to heal BONE FRACTURES and to treat METABOLIC BONE DISEASES such as OSTEOPOROSIS.
• Chemical Structure [CS] - Ergocalciferols
• Established Pharmacologic Class [EPC] - Vitamin D2 Analog

Synonyms

Doxercalciferol; 54573-75-0; 1-Hydroxyergocalciferol; 1alpha-Hydroxyergocalciferol; Hectorol; 1alpha-hydroxyvitamin D2; 1-alpha-Hydroxyvitamin D2; 1-alpha-hydroxyergocalciferol; Doxercalciferolum; 3DIZ9LF5Y9; (1S,3R,5Z,7E,22E)-9,10-Secoergosta-5,7,10,22-tetraene-1,3-diol; TSA-840; GZ427397; CHEBI:4712; doxacalciferol; 9,10-Secoergosta-5,7,10(19),22-tetraene-1,3-diol, (1alpha,3beta,5Z,7E,22E)-

Frequently Asked Questions

What are the CAS number and molecular formula of Vitamin D2, 1a-Hydroxy-?

CAS 54573-75-0; molecular formula C28H44O2; molecular weight — g/mol.

What other names is Vitamin D2, 1a-Hydroxy- known by?

Doxercalciferol, 54573-75-0, 1-Hydroxyergocalciferol, 1alpha-Hydroxyergocalciferol, Hectorol, 1alpha-hydroxyvitamin D2.

Is Vitamin D2, 1a-Hydroxy- classified as hazardous?

Hazard statements reported: H300.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.