华法林

Description

Warfarin · CAS 951658-59-6 · C19H16O4. UNII 5Q7ZVV76EI. Boiling Point: 356 °C @760 [mm Hg]; Melting Point: 322 °F (EPA, 1998); Melting Point: 161.

Identification

CAS Registry Number	951658-59-6
PubChem CID	54678486
Molecular formula	C19H16O4
IUPAC name	4-hydroxy-3-(3-oxo-1-phenylbutyl)chromen-2-one
UNII (FDA)	5Q7ZVV76EI

Computed Descriptors

Molecular Weight	308.3
XLogP3	2.7
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	4
Exact Mass	308.10485899
Monoisotopic Mass	308.10485899
Topological Polar Surface Area	63.6
Heavy Atom Count	23
Formal Charge	0

Physical & Chemical Properties

Boiling Point	356 °C @760 [mm Hg]
Melting Point	322 °F (EPA, 1998)
Melting Point	161
Melting Point	161 °C
Melting Point	322 °F
Solubility	0.002 % (NIOSH, 2024)
Solubility	17
Solubility	In water, 17 mg/L at 20 °C
Solubility	0.017 mg/mL at 20 °C
Solubility	0.002%

Physical description & handling notes

• Warfarin is an odorless and colorless solid. Used as a rodenticide for Norway rats and for house mice. (EPA, 1998)
• Colorless, odorless, crystalline powder. [rodenticide]; [NIOSH]
• Solid
• COLOURLESS-TO-WHITE POWDER.
• Colorless, odorless, crystalline powder or solid.
• Colorless, odorless, crystalline powder. [Note: Rodenticide.]

GHS Hazard Classification

Reported hazard statements	H300, H310, H330, H372, H411, H312 (18.9%), H319 (17.4%), H360 (98%)

Documented Uses

• Warfarin and its sodium salt are registered for use in controlling rats and mice; has been used successfully against common vampire bats; a blood anticoagulant; its sodium salt is used medically to treat people with blood hypercoagulation problems; [HSDB] Warfarin competes with vitamin K and inhibits hepatic synthesis of clotting factors to increase the prothrombin time. Typical therapeutic doses are 2 to 10 mg/day. [ACGIH]
• Warfarin and its sodium salt are registered for use in controlling commensal rodents (rats and mice) in and around homes, animal and agricultural premises, and commercial and industrial sites.
• Warfarin is a blood anticoagulant; its sodium salt is used medically to treat people with blood hypercoagulation problems.
• ... Warfarin has been used successfully against common vampire bats.
• For more Uses (Complete) data for WARFARIN (6 total), please visit the HSDB record page.
• Use (kg; approx.) in Germany (2009): >25

Synonyms

warfarin; 81-81-2; Coumafene; Zoocoumarin; Coumafen; Brumolin; Coumefene; Dethmor; Kumader; Warfarine; Kumadu; Vampirinip II; Coumarins; Kypfarin; Rodafarin; Solfarin

Frequently Asked Questions

What are the CAS number and molecular formula of Warfarin?

CAS 951658-59-6; molecular formula C19H16O4; molecular weight — g/mol.

What other names is Warfarin known by?

warfarin, 81-81-2, Coumafene, Zoocoumarin, Coumafen, Brumolin.

Is Warfarin classified as hazardous?

Hazard statements reported: H300, H310, H330, H372, H411.

What are the key physical properties of Warfarin?

Boiling Point: 356 °C @760 [mm Hg]; Melting Point: 322 °F (EPA, 1998); Melting Point: 161; Melting Point: 161 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.