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硫唑嘌呤 USP

CAS 446-86-6C9H7N7O2SMW 277.27

硫唑嘌呤 USP,CAS 登记号 446-86-6,由济南圣和化工有限公司现货供应,可提供纯度 按批次COA提供(不公开发布) 的规格,下游主要用于医药中间体及原料药。支持样品与小批量试用,批量价格请联系我们获取,验收以批次 COA 为准。

规格参数

CAS号446-86-6
分子式C9H7N7O2S
分子量277.27
熔点243.5
LogP0.1
纯度按批次COA提供(不公开发布)
包装按订单/批次确认(不公开发布)
应用领域医药中间体及原料药
类别医药中间体及原料药

用途与场景

医药中间体及原料药

包装与供货

包装规格按订单/批次确认(不公开发布)
纯度规格按批次COA提供(不公开发布)
储存条件密封、阴凉干燥处保存
供货周期现货/按订单安排

文件与支持

每批随货提供 COA;可按需提供 MSDS 及技术文件。邮件注明产品名称与 CAS 号,一个工作日内回复报价。

常见问题

在哪里能查到 硫唑嘌呤 USP 的 CAS 号?

本页已列出 硫唑嘌呤 USP 的 CAS 号:446-86-6,可与随货 COA 核对。

可以提供哪些规格和包装?

常见纯度为 按批次COA提供(不公开发布),包装形式为 按订单/批次确认(不公开发布),特殊规格可在询价时说明。

硫唑嘌呤 USP 一般用在什么产品里?

主要涉及医药中间体及原料药。

下单流程是怎样的?

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PubChem 公开数据

Description

Azathioprine · CAS 446-86-6 · C9H7N7O2S. UNII MRK240IY2L. Melting Point: 243.5; Melting Point: dec 243-244 °C; Melting Point: 243.5 °C.

Identification

CAS Registry Number446-86-6
PubChem CID2265
Molecular formulaC9H7N7O2S
IUPAC name6-(3-methyl-5-nitroimidazol-4-yl)sulfanyl-7H-purine
UNII (FDA)MRK240IY2L

Computed Descriptors

Molecular Weight277.27
XLogP30.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count2
Exact Mass277.03819367
Monoisotopic Mass277.03819367
Topological Polar Surface Area143
Heavy Atom Count19
Formal Charge0

Physical & Chemical Properties

Melting Point243.5
Melting Pointdec 243-244 °C
Melting Point243.5 °C
Solubility1.07e+00 g/L
LogP0.1
LogPlog Kow = 0.10
LogP0.7
LogP0.89
Dissociation Constants7.87 (at 25 °C)
Dissociation ConstantspKa = 8.2

Physical description & handling notes

  • Azathioprine appears as pale yellow crystals or yellowish powder. Decomposes at 243-244 °C. Used for the treatment of rheumatoid arthritis. A known carcinogen.
  • Solid
  • Pale yellow crystals from 50% aq acetone
  • 469 to 471 °F (decomposes) (NTP, 1992)
  • less than 1 mg/mL at 73 °F (NTP, 1992)
  • Insoluble

GHS Hazard Classification

Reported hazard statementsH302 (100%), H315 (88.8%), H319 (88.8%), H335 (87.9%), H340 (62.6%), H350 (100%), H360 (58.9%), H317

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

H315 (88.8%): Causes skin irritation [Warning Skin corrosion/irritation]

Documented Uses

  • Used as an immunosuppressant and anticancer drug; [Kanerva, p. 1753]
  • Use (kg; approx.) in Germany (2009): >2500
  • Use (kg; exact) in Germany (2009): 3323
  • Consumption (g per capita; approx.) in Germany (2009): 0.0305
  • Consumption (g per capita; exact) in Germany (2009): 0.0406
  • Consumption (g per capita) in the USA (2002): 0.00253

Synonyms

azathioprine; 446-86-6; Azothioprine; Azanin; Azathioprin; Azatioprin; Azamun; Azasan; Ccucol; Imurek; Muran; NSC-39084; Azathioprinum; Azatioprina; BW 57-322; BW-57-322

Frequently Asked Questions

What are the CAS number and molecular formula of Azathioprine?

CAS 446-86-6; molecular formula C9H7N7O2S; molecular weight — g/mol.

What other names is Azathioprine known by?

azathioprine, 446-86-6, Azothioprine, Azanin, Azathioprin, Azatioprin.

Is Azathioprine classified as hazardous?

Hazard statements reported: H302, H315, H319, H335, H340.

What are the key physical properties of Azathioprine?

Melting Point: 243.5; Melting Point: dec 243-244 °C; Melting Point: 243.5 °C; Solubility: 1.07e+00 g/L.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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