阿齐沙坦

阿齐沙坦（CAS 147403-03-0）的公开数据库记录，列此仅供独立核对。

危险化学品分类与危害说明

物理形态与操作说明

• Colorless prisms from ethanol
• Stable under recommended storage conditions.
• Hazardous decomposition products formed under fire conditions. - Carbon oxides, nitrogen oxides (NOx).
• pKa at 0.1 N NaOH (26 eg C): 6.1
• Crystals from ethanol /Azilsartan medoxomil/
• Crystals; mp 196 °C (decomposes). Freely soluble in methanol. Practically insolluble in water /Azilsartan kamedoxomil/

公开数据库收录的理化数据

这个物质在各数据库里的编号

数据库记载的用途

• Preparation: T. Naka, Y. Inada, European Patent Office patent 0520423; eidem, United States of America patent 5243054 (1992, 1993 both to Takeda).
• United States Food and Drug Administration–Approved Indications
• Azilsartan is an angiotensin II receptor blocker (ARB) used in the therapy of hypertension. It is associated with a low rate of transient serum aminotransferase elevations, but has yet to be linked to instances of acute liver injury.
• Breast Feeding; Lactation; Milk, Human; Antihypertensive Agents; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Blockers
• Angiotensin II Receptor Antagonists
• Edarbi is an angiotensin II receptor blocker (ARB) indicated for the treatment of hypertension to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes, including the class to which this drug principally belongs. /Included in US product label/

它在各数据库里的别名

Azilsartan; 147403-03-0; TAK-536; TAK 536; F9NUX55P23; 2-ethoxy-3-[[4-[2-(5-oxo-2H-1,2,4-oxadiazol-3-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylic acid; CHEBI:68850; DTXSID70163712; 2-ethoxy-3-((4-(2-(5-oxo-2H-1,2,4-oxadiazol-3-yl)phenyl)phenyl)methyl)benzimidazole-4-carboxylic acid; RefChem:54400; DTXCID1086203; Azilsartan [USAN]; AZILSARTAN [INN]; MFCD20278186; C25H20N4O5; CHEMBL57242

计算机算出的分子描述符

数据库摘要

Azilsartan · CAS 147403-03-0 · C25H20N4O5. UNII F9NUX55P23. 熔点: 212-214 °C; LogP: log Kow = 0.90.

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。