阿格列汀

阿格列汀（CAS 850649-61-5）的公开数据库记录，列此仅供独立核对。

危险化学品分类与危害说明

物理形态与操作说明

• Sparingly soluble
• Stable if stored as directed; avoid strong oxidizing agents
• Thermal decomposition may produce toxic gases such as carbon monoxide, carbon dioxide, and nitrogen oxides.
• White to off-white crystalline powder; soluble in dimethylsulfoxide; sparingly soluble in water, methanol; slightly soluble in ethanol; very slightly soluble in octanol, isopropyl acetate /Alogliptin benzoate/
• Table: Alogliptin benzoate Preparations [Table#8191]
• Table: Alogliptin benzoate Combinations Preparations [Table#8192]

这个物质在各数据库里的编号

数据库记载的用途

• Indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
• Type 2 diabetes (T2D) is a chronic illness that is increasingly diagnosed among children and adults in the United States of America. According to the Centers for Disease Control and Prevention (CDC), approximately 100 million adults in the United States of America had either diabetes or prediabetes in 2015. T2D is the seventh leading cause of death and is associated with a 2- to 4-fold increased risk of cardiovascular disease. Effective glucose control is essential for managing the condition. The American Diabetes
• Alogliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor which is used in combination with diet and exercise in the therapy of type 2 diabetes, either alone or in combination with other oral hypoglycemic agents. Alogliptin has been reported to cause liver injury, but the characteristics and details of the injury have not been defined in the published literature.
• Breast Feeding; Lactation; Milk, Human; Hypoglycemic Agents; Incretins; Dipeptidyl-Peptidase IV Inhibitors; DPP-4 Inhibitors
• Alogliptin (Class: Other Substances, Added Date: 05-2015)
• Nesina is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus in multiple clinical settings. /Included in US product label/

它在各数据库里的别名

Alogliptin; 850649-61-5; alogliptina; alogliptine; vipidia; alogliptinum; JHC049LO86; 2-({6-[(3r)-3-Aminopiperidin-1-Yl]-3-Methyl-2,4-Dioxo-3,4-Dihydropyrimidin-1(2h)-Yl}methyl)benzonitrile; HSDB 8203; CHEBI:72323; DTXSID90234130; 2-((6-((3R)-3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl) benzonitrile; alogliptin tartrate; 2-((6-((3R)-3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile; RefChem:57142; A10BH04

计算机算出的分子描述符

数据库摘要

Alogliptin · CAS 850649-61-5 · C18H21N5O2. UNII JHC049LO86.

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。