阿西替尼

阿西替尼（CAS 319460-85-0）的公开数据库记录，列此仅供独立核对。

危险化学品分类与危害说明

物理形态与操作说明

• In aqueous media with a pH between 1.1 to 7.8, axitinib has a solubility of over 0.2 μg/mL.
• Axitinib prevents the progression of cancer by inhibiting angiogenesis and blocking tumor growth.

公开数据库收录的理化数据

这个物质在各数据库里的编号

数据库记载的用途

• Used in kidney cell cancer and investigated for use/treatment in pancreatic and thyroid cancer.
• Breast Feeding; Lactation; Milk, Human; Antineoplastic Agents; Enzyme Inhibitors; Protein Kinase Inhibitors; Signal Transduction Inhibitors; Tyrosine Kinase Inhibitors
• • Renal cell carcinoma (a type of kidney cancer) that is advanced. It is used:
• • With avelumab or pembrolizumab as the first treatment.
• • Alone in patients whose cancer did not get better after one treatment with systemic therapy.
• Axitinib is also being studied in the treatment of other types of cancer.

它在各数据库里的别名

Axitinib; 319460-85-0; Inlyta; AG-13736; axitinibum; C9LVQ0YUXG; DTXSID3049049; AG013736; NSC-757441; N-methyl-2-((3-((1E)-2-(pyridin-2-yl)ethenyl)-1H-indazol-6-yl)sulfanyl)benzamide; N-methyl-2-({3-[(E)-2-(pyridin-2-yl)ethenyl]-1H-indazol-6-yl}sulfanyl)benzamide; DTXCID8028975; CHEBI:66910; Benzamide, N-methyl-2-((3-((E)-2-(2-pyridinyl)ethenyl)-1H-indazol-6-yl)thio)-; N-methyl-2-({3-[(1E)-2-(pyridin-2-yl)ethenyl]-1H-indazol-6-yl}sulfanyl)benzamide; Benzamide, N-methyl-2-((3-((1E)-2-(2-pyridinyl)ethenyl)-1H-indazo)-6-yl)thio)-

计算机算出的分子描述符

数据库摘要

Axitinib · CAS 319460-85-0 · C22H18N4OS. UNII C9LVQ0YUXG. LogP: 3.8; Dissociation Constants: 4.8.

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。