阿维拉霉素

阿维拉霉素（CAS 11051-71-1）的公开数据库记录，列此仅供独立核对。

危险化学品分类与危害说明

法规与备案状态

物理形态与操作说明

• Colorless, needle-shaped crystals from acetone-ether
• Colorless needles from chloroform/petroleum ether; MW: 1404.25; MP: 181-182 °C (1-2.H2O). UV max (methanol): 227, 286 nm (log epsilon 4.12, 3.33) /Avilamycin A/
• Specific optical rotation at 20 °C/D = +0.8 deg (c = 1.165 in absolute ethanol); -7.7 deg (c = 1.083 in chloroform)
• Oligosaccharide antibiotics are sensitive to acid pH because of the ortho-ester linkages. Acidic phenolic group makes them relatively unstable to handling conditions.
• Dihydrate; colorless fine plates from acetone/ether; MP: 188-189 °C. Specific optical rotation at 20 °C/D: -4.8 deg (C = 1.44 in chloroform). UV Max (methanol): 228, 284 nm (log epsilon 4.12, 3.33) /Avilamycin C/
• Reactive groups are the glycosidic linkages, the hydroxyl groups, the carbonyl groups, and the phenolic groups.

公开数据库收录的理化数据

这个物质在各数据库里的编号

数据库记载的用途

• Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients
• Veterinary Drug -> ANTIMICROBIAL_AGENT -> JECFA Functional Classes
• Polyether antibiotic complex produced by Streptromyces viridochromogenes, ETH 23575 (NRRL 2860) ... Isoln: E. Gaeumann et al., German patent 1116864; eidem, USA patent 3131126 (1961, 1964 both to Ciba-Geigy).
• Avilamycin A is the main component; avilamycins B through N are also known and are derivatives of A differing at the C-45 linkage and/or the C-56 ketone adduct.
• MEDICATION (VET): Avilamycin is mainly active against Gram-positive bacteria, including Bacillus spp., Clostridium spp., Corynebacterium bovis, Enterococcus spp., Lactobacillus spp., Listeria monocytogenes, Micrococcus luteus, Staphylococcus aureus and Streptococcus spp. Avilamycin is intended for use as a veterinary medicine in chickens, turkeys, pigs and rabbits to control bacterial enteric infections.
• MEDICATION (VET): For the reduction in incidence and overall severity of diarrhea in the presence of pathogenic Escherichia coli in groups of weaned pigs. /Included in US product label/

它在各数据库里的别名

Avilamycin; Avilamycina; Avilamycine; Avilamycinum; 11051-71-1; LY 048 740; DTXSID40891398; 720WDX56D3; avilamicina; Inteprity; Kavault; RefChem:57998; DTXCID701030518; LY-048740; Surmax; C61H88Cl2O32

计算机算出的分子描述符

数据库摘要

Avilamycin · CAS 11051-71-1 · C61H88Cl2O32. UNII 720WDX56D3. 熔点: 188-189.5 °C.

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。