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阿必鲁肽

CAS 782500-75-8C148H223N39O46MW 3284.6

阿必鲁肽(CAS 782500-75-8):分子式 C148H223N39O46、分子量 3284.6;类别 医药中间体及原料药。

产品描述

阿必鲁肽(CAS 782500-75-8)是一种医药中间体及原料药原料。其分子式 C148H223N39O46 由 148 个碳、223 个氢、39 个氮、46 个氧 组成。 分子量约为 3284.6。公开物性数据显示其LogP 约 -14。作为化工品采购代理与分销渠道,我们可在国内及跨境渠道为阿必鲁肽寻源比价,并安排小批量试样与批次采购;下单前提供完整 COA、质检报告与合规文件,验收以批次 COA 为准。

规格参数

CAS号782500-75-8
分子式C148H223N39O46
分子量3284.6
LogP-14
应用领域MEDICATION、Tanzeum is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. /Included in US product label/、Incretins、Antidiabetic、Methods of Manufacturing: Albiglutide is produced in Saccharomyces cerevisiae using recombinant deoxyribonucleic acid (DNA) technology. The albiglutide drug substance manufacturing process consists of a series of steps which include cell culture、harvest
类别医药中间体及原料药

用途与场景

登记用途:MEDICATION、Tanzeum is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. /Included in US product label/、Incretins、Antidiabetic、Methods of Manufacturing: Albiglutide is produced in Saccharomyces cerevisiae using recombinant deoxyribonucleic acid (DNA) technology. The albiglutide drug substance manufacturing process consists of a series of steps which include cell culture、harvest。

采购档案

这个产品是什么

阿必鲁肽 是一种医药中间体或原料药类化合物,登记 CAS 号为 782500-75-8,分子式 C148H223N39O46(分子量 3284.6),归属于医药中间体及原料药大类化工原料。

识别信息

登记 CAS 号:782500-75-8

其分子式 C148H223N39O46 由 148 个碳、223 个氢、39 个氮、46 个氧 组成。

别名/同义词:阿必鲁肽 · Albiglutide

所属分类:医药中间体及原料药

常见问题

阿必鲁肽 的 CAS 号是多少?

阿必鲁肽 的 CAS 登记号为 782500-75-8。

阿必鲁肽 的分子式与分子量是多少?

分子式 C148H223N39O46,分子量 3284.6。

阿必鲁肽 还有哪些别名?

别名/同义词:阿必鲁肽、Albiglutide。

阿必鲁肽 的登记用途是什么?

登记用途:MEDICATION、Tanzeum is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. /Included in US product label/、Incretins、Antidiabetic、Methods of Manufacturing: Albiglutide is produced in Saccharomyces cerevisiae using recombinant deoxyribonucleic acid (DNA) technology. The albiglutide drug substance manufacturing process consists of a series of steps which include cell culture、harvest。

阿必鲁肽 属于哪个分类?

所属分类:医药中间体及原料药。

如何在 591daili.cn 采购 阿必鲁肽?

请在联系页面提交产品名称、CAS 号与数量,我们作为采购代理在国内及跨境渠道为您寻源比价,安排试样与批次采购,下单前提供 COA 与合规文件。

包装与单证

包装按订单确认,从实验室小包装到吨袋大货,随订单安排而非在页面上写死。每批随货附 COA 分析证书,可另提供 MSDS;若终端用途带有法规限度(食品接触、药品或化妆品),请在询价时说明执行标准,等级按该标准确定。

PubChem 公开数据

阿必鲁肽(CAS 782500-75-8)的公开数据库记录,列此仅供独立核对。

物理形态与操作说明

  • White to yellow powder
  • Chemical stability: Material is stable under normal conditions.
  • Hazardous decomposition products: Irritating and/or toxic fumes and gases may be emitted upon the products decomposition.
  • Solvent is clear, colorless; reconstituted solution is yellow
  • Table: Albiglutide Preparations [Table#8276]
  • Eperzan

这个物质在各数据库里的编号

CAS Registry Number782500-75-8
PubChem CID122173812
分子式C148H223N39O46
UNII(FDA)5E7U48495E

数据库记载的用途

  • Tanzeum is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. /Included in US product label/
  • Albiglutide is produced in Saccharomyces cerevisiae using recombinant deoxyribonucleic acid (DNA) technology. The albiglutide drug substance manufacturing process consists of a series of steps which include cell culture, harvest, and purification stages.
  • Preparation: C. A. Rosen, W. A. Haseltine, World Intellectual Property Organization patent 03059934; C. A. Rosen et al., USA patent 7141547 (2003, 2006 both to Human Genome Sciences).
  • Indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
  • Albiglutide is a recombinant DNA produced polypeptide analogue of human glucagon-like peptide-1 (GLP-1) which is used in combination with diet and exercise in the therapy of type 2 diabetes, either alone or in combination with other antidiabetic agents. There have been no published reports of hepatotoxicity attributed to albiglutide therapy.
  • /BOX WARNING/ Carcinogenicity of albiglutide could not be assessed in rodents, but other glucagon-like peptide-1 (GLP-1) receptor agonists have caused thyroid C-cell tumors in rodents at clinically relevant exposures. Human relevance of GLP-1 receptor agonist induced C-cell tumors in rodents has not been determined. It is unknown whether Tanzeum causes thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in humans.

它在各数据库里的别名

albiglutidum; Albiglutida; RefChem:141; A10BJ04; Albiglutide (genetical recombination); 5E7U48495E; 782500-75-8; Albiglutide; Eperzan; GSK-716155; GSK716155; Tanzeum; CHEBI:78425; SCHEMBL29349999; CHEBI:136045; HGB50075

计算机算出的分子描述符

分子量3284.6
XLogP3-14
氢键供体数49
氢键受体数51
可旋转键数109
精确质量3283.6342956
单同位素质量3282.6309408
拓扑极性表面积1380
重原子数233
形式电荷0

数据库摘要

Albiglutide · CAS 782500-75-8 · C148H223N39O46. UNII 5E7U48495E.

数据来源:PubChem / Wikidata;与随货 COA 不一致时以 COA 为准。

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