盐酸安西他滨

Description

Cyclocytidine hydrochloride · CAS 10212-25-6 · C9H12ClN3O4. UNII 3T6920M469. Solubility: H2O 200 ( mg/mL); Solubility: EtOAc < 0.1 ( mg/mL); Solubility: CHC13 < 0.1 ( mg/mL).

Identification

CAS Registry Number	10212-25-6
PubChem CID	25050
Molecular formula	C9H12ClN3O4
IUPAC name	(2R,4R,5R,6S)-4-(hydroxymethyl)-10-imino-3,7-dioxa-1,9-diazatricyclo[6.4.0.02,6]dodeca-8,11-dien-5-ol;hydrochloride
UNII (FDA)	3T6920M469

Computed Descriptors

Molecular Weight	261.66
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	1
Exact Mass	261.0516336
Monoisotopic Mass	261.0516336
Topological Polar Surface Area	98.4
Heavy Atom Count	17
Formal Charge	0
Complexity	394

Physical & Chemical Properties

Solubility	H2O 200 ( mg/mL)
Solubility	EtOAc < 0.1 ( mg/mL)
Solubility	CHC13 < 0.1 ( mg/mL)

Physical description & handling notes

• Bulk: A sample stored at 60°C for 30 days showed no decomposition as indicated by optical rotation. Solution: A 1% solution in water after 24 hours at room temperature showed no decomposition as indicated by optical rotation.
• (c = H20) [a]20D = -22 ± 2 degrees
• 141.5 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

GHS Hazard Classification

Reported hazard statements	H315 (100%), H319 (100%), H335 (100%)

Documented Uses

• Substances that counteract or neutralize acidity of the GASTROINTESTINAL TRACT.

Synonyms

Cyclocytidine hydrochloride; ANCITABINE HYDROCHLORIDE; 10212-25-6; 2,2'-O-Cyclocytidine hydrochloride; 2,2'-Cyclocytidine hydrochloride; Cyclocytidine HCl; ancitabine HCl; 2,2'-Anhydrocytidine hydrochloride; 2,2'-Anhydrocytarabine hydrochloride; 2,2'-Anhydroaracytidine hydrochloride; NSC-145668; 2,2'-Anhydroarabinosylcytosine hydrochloride; 3T6920M469; CHEBI:74843; CycloCMP hydrochloride; Ancytabine Hydrochloride

Frequently Asked Questions

What are the CAS number and molecular formula of Cyclocytidine hydrochloride?

CAS 10212-25-6; molecular formula C9H12ClN3O4; molecular weight — g/mol.

What other names is Cyclocytidine hydrochloride known by?

Cyclocytidine hydrochloride, ANCITABINE HYDROCHLORIDE, 10212-25-6, 2,2'-O-Cyclocytidine hydrochloride, 2,2'-Cyclocytidine hydrochloride, Cyclocytidine HCl.

Is Cyclocytidine hydrochloride classified as hazardous?

Hazard statements reported: H315, H319, H335.

What are the key physical properties of Cyclocytidine hydrochloride?

Solubility: H2O 200 ( mg/mL); Solubility: EtOAc < 0.1 ( mg/mL); Solubility: CHC13 < 0.1 ( mg/mL).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.