盐酸丁螺环酮

盐酸丁螺环酮（CAS 33386-08-2）的公开数据库记录，列此仅供独立核对。

危险化学品分类与危害说明

物理形态与操作说明

• 197.7 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

这个物质在各数据库里的编号

数据库记载的用途

• For the management of anxiety disorders or the short-term relief of the symptoms of anxiety, and also as an augmention of SSRI-treatment against depression.
• Agents that alleviate ANXIETY, tension, and ANXIETY DISORDERS, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. ADRENERGIC BETA-ANTAGONISTS are commonly used in the symptomatic treatment of anxiety but are not included here.
• Endogenous compounds and drugs that bind to and activate SEROTONIN RECEPTORS. Many serotonin receptor agonists are used as ANTIDEPRESSANTS; ANXIOLYTICS; and in the treatment of MIGRAINE DISORDERS.
• Metabolized hepatically, primarily by oxidation by cytochrome P450 3A4 producing several hydroxylated derivatives and a pharmacologically active metabolite, 1-pyrimidinylpiperazine (1-PP) Route of Elimination: In a single-dose study using 14C-labeled buspirone, 29% to 63% of the dose was excreted in the urine within 24 hours, primarily as metabolites; fecal excretion accounted for 18% to 38% of the dose. Half Life: 2-3 hours (although the action of a single dose is much longer than the short halflife indicates).

它在各数据库里的别名

Buspirone hydrochloride; 33386-08-2; Buspirone HCL; Spamilan; MJ 9022-1; NSC-751138; NSC-759571; 207LT9J9OC; APD405; MJ-9022-1; APD-405; N-(4-(4-(2-Pyrimidinyl)-1-piperazinyl)butyl)-1,1-cyclopentanediacetamide monohydrochloride; CHEBI:3224; DTXSID1037193; 8-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]-8-azaspiro[4.5]decane-7,9-dione hydrochloride; 8-Azaspiro[4.5]decane-7,9-dione, 8-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-, monohydrochloride

计算机算出的分子描述符

数据库摘要

buspirone hydrochloride · CAS 33386-08-2 · C21H32ClN5O2. UNII 207LT9J9OC.

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。