巴瑞克替尼

巴瑞克替尼（CAS 1187594-09-7）的公开数据库记录，列此仅供独立核对。

危险化学品分类与危害说明

公开数据库收录的理化数据

这个物质在各数据库里的编号

数据库记载的用途

• Baricitinib is a disease-modifying antirheumatic drug (DMARD) indicated for rheumatoid arthritis when conventional DMARDs prove inadequate.
• Baricitinib is an orally available small molecule inhibitor of Janus kinases that is used to treat moderate-to-severe rheumatoid arthritis, severe alopecia areata, and, in combination with remdesivir, severe COVID-19 in hospitalized patients requiring supplementary oxygen. Baricitinib is associated with transient and usually mild elevations in serum aminotransferase levels during therapy but has yet to be linked to cases of clinically apparent acute liver injury.
• Breast Feeding; Lactation; Milk, Human; Antirheumatic Agents; Enzyme Inhibitors; Janus Kinase Inhibitors; JAK Inhibitors; Signal Transduction Inhibitors; Protein Kinase Inhibitors
• Baricitinib (Class: Other Substances, Added Date: 03-2022)
• Take with or without food. A high-fat meal can decrease the mean AUC and Cmax of baricitinib and delay Tmax, but not to a clinically singificant extent.
• Established Pharmacologic Class [EPC] - Janus Kinase Inhibitor

它在各数据库里的别名

Baricitinib; 1187594-09-7; olumiant; LY3009104; INCB028050; INCB 028050; INCB-028050; 2-(3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-1-(ethylsulfonyl)azetidin-3-yl)acetonitrile; LY-3009104; LY 3009104; ISP4442I3Y; DTXCID5074719; CHEBI:95341; DTXSID30152228; L04AA37; 3-Azetidineacetonitrile, 1-(ethylsulfonyl)-3-(4-(7H-pyrrolo(2,3-d)pyrimidin-4-yl)-1H-pyrazol-1-yl)-

计算机算出的分子描述符

数据库摘要

Baricitinib · CAS 1187594-09-7 · C16H17N7O2S. UNII ISP4442I3Y. 沸点: 707.2.

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。