倍他洛尔

Description

Betaxolol · CAS 63659-18-7 · C18H29NO3. UNII O0ZR1R6RZ2. Melting Point: 70-72 °C; Melting Point: 70 - 72 °C; Solubility: 451.

Identification

CAS Registry Number	63659-18-7
PubChem CID	2369
Molecular formula	C18H29NO3
IUPAC name	1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-(propan-2-ylamino)propan-2-ol
UNII (FDA)	O0ZR1R6RZ2

Computed Descriptors

Molecular Weight	307.4
XLogP3	2.8
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	11
Exact Mass	307.21474379
Monoisotopic Mass	307.21474379
Topological Polar Surface Area	50.7
Heavy Atom Count	22
Formal Charge	0

Physical & Chemical Properties

Melting Point	70-72 °C
Melting Point	70 - 72 °C
Solubility	451
Solubility	2.98e-02 g/L
LogP	2.81
LogP	2.4
Dissociation Constants	9.21
Dissociation Constants	9.4

Physical description & handling notes

• Solid

GHS Hazard Classification

Reported hazard statements	H302 (100%), H361 (100%), H412 (100%)

Documented Uses

• Use (kg; approx.) in Germany (2009): >100
• Consumption (g per capita; approx.) in Germany (2009): 0.00122
• For the management of hypertension.
• Betaxolol is a lipophilic β-adrenergic blocker selective to the β-1 adrenergic receptor, with a limited β-2 blocking effect. This factor is an important distinction compared to topical nonselective β-blockers. Betaxolol can be administered by topical (ophthalmic) or systemic (oral) routes.
• Betaxolol is a cardioselective beta-blocker used in the treatment of hypertension. Betaxolol has not been linked to instances of clinically apparent drug induced liver injury.
• Breast Feeding; Lactation; Milk, Human; Antihypertensive Agents; Adrenergic Beta-Antagonists; Antiglaucoma Agents; Antiarrhythmics

Synonyms

betaxolol; 63659-18-7; Betaxololum; DTXSID2022674; SL 75212; O0ZR1R6RZ2; 1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-(propan-2-ylamino)propan-2-ol; 1-(4-(2-(Cyclopropylmethoxy)ethyl)phenoxy)-3-((1-methylethyl)amino)-2-propanol; ALO-140102 FREE BASE; 2-Propanol, 1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-((1-methylethyl)amino)-; SL-7521210 FREE BASE; CHEBI:3082; DTXCID102674; 1-(isopropylamino)-3-[p-(cyclopropylmethoxyethyl)phenoxy]-2-propanol; 1-{4-[2-(Cyclopropylmethoxy)ethyl]phenoxy}-3-[(propan-2-yl)amino]propan-2-ol; 1-{4-[2-(cyclopropylmethoxy)ethyl]phenoxy}-3-(propan-2-ylamino)propan-2-ol

Frequently Asked Questions

What are the CAS number and molecular formula of Betaxolol?

CAS 63659-18-7; molecular formula C18H29NO3; molecular weight — g/mol.

What other names is Betaxolol known by?

betaxolol, 63659-18-7, Betaxololum, DTXSID2022674, SL 75212, O0ZR1R6RZ2.

Is Betaxolol classified as hazardous?

Hazard statements reported: H302, H361, H412.

What are the key physical properties of Betaxolol?

Melting Point: 70-72 °C; Melting Point: 70 - 72 °C; Solubility: 451; Solubility: 2.98e-02 g/L.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.