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波普瑞韦

CAS 394730-60-0C27H45N5O5MW 519.7

波普瑞韦(CAS 394730-60-0):分子式 C27H45N5O5、分子量 519.7;类别 医药中间体及原料药。

产品描述

波普瑞韦(CAS 394730-60-0)是一种医药中间体及原料药原料。其分子式 C27H45N5O5 由 27 个碳、45 个氢、5 个氮、5 个氧 组成。 分子量约为 519.7。公开物性数据显示其LogP 约 3.1。作为化工品采购代理与分销渠道,我们可在国内及跨境渠道为波普瑞韦寻源比价,并安排小批量试样与批次采购;下单前提供完整 COA、质检报告与合规文件,验收以批次 COA 为准。

规格参数

CAS号394730-60-0
分子式C27H45N5O5
分子量519.7
LogP3.1
应用领域MEDICATION、Formulations/Preparations: VICTRELIS 200 mg Capsules、red-colored cap with the Merck logo printed in yellow ink、and a yellow-colored body with "314" printed in red ink、Manufactured as an approximately equal mixture of two diasteromers
类别医药中间体及原料药

用途与场景

登记用途:MEDICATION、Formulations/Preparations: VICTRELIS 200 mg Capsules、red-colored cap with the Merck logo printed in yellow ink、and a yellow-colored body with "314" printed in red ink、Manufactured as an approximately equal mixture of two diasteromers。

采购档案

这个产品是什么

波普瑞韦 是一种医药中间体或原料药类化合物,登记 CAS 号为 394730-60-0,分子式 C27H45N5O5(分子量 519.7),归属于医药中间体及原料药大类化工原料。

识别信息

登记 CAS 号:394730-60-0

其分子式 C27H45N5O5 由 27 个碳、45 个氢、5 个氮、5 个氧 组成。

别名/同义词:波普瑞韦 · Boceprevir

所属分类:医药中间体及原料药

常见问题

波普瑞韦 的 CAS 号是多少?

波普瑞韦 的 CAS 登记号为 394730-60-0。

波普瑞韦 的分子式与分子量是多少?

分子式 C27H45N5O5,分子量 519.7。

波普瑞韦 还有哪些别名?

别名/同义词:波普瑞韦、Boceprevir。

波普瑞韦 的登记用途是什么?

登记用途:MEDICATION、Formulations/Preparations: VICTRELIS 200 mg Capsules、red-colored cap with the Merck logo printed in yellow ink、and a yellow-colored body with "314" printed in red ink、Manufactured as an approximately equal mixture of two diasteromers。

波普瑞韦 属于哪个分类?

所属分类:医药中间体及原料药。

如何在 591daili.cn 采购 波普瑞韦?

请在联系页面提交产品名称、CAS 号与数量,我们作为采购代理在国内及跨境渠道为您寻源比价,安排试样与批次采购,下单前提供 COA 与合规文件。

包装与单证

包装按订单确认,从实验室小包装到吨袋大货,随订单安排而非在页面上写死。每批随货附 COA 分析证书,可另提供 MSDS;若终端用途带有法规限度(食品接触、药品或化妆品),请在询价时说明执行标准,等级按该标准确定。

PubChem 公开数据

波普瑞韦(CAS 394730-60-0)的公开数据库记录,列此仅供独立核对。

危险化学品分类与危害说明

Reported hazard statementsH302 (92.9%), H361 (92.9%)

H302 (92.9%): Harmful if swallowed [Warning Acute toxicity, oral]

H361 (92.9%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]

物理形态与操作说明

  • White to off-white amorphous powder
  • Slightly soluble in water
  • Freely soluble in methanol, ethanol, and isopropanol
  • Boceprevir is classified as a direct-acting antiviral (DAA) and prevents viral replication in HCV genotype 1.
  • VICTRELIS 200 mg Capsules, red-colored cap with the Merck logo printed in yellow ink, and a yellow-colored body with "314" printed in red ink.

这个物质在各数据库里的编号

CAS Registry Number394730-60-0
PubChem CID10324367
分子式C27H45N5O5
IUPAC 名称(1R,2S,5S)-N-(4-amino-1-cyclobutyl-3,4-dioxobutan-2-yl)-3-[(2S)-2-(tert-butylcarbamoylamino)-3,3-dimethylbutanoyl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide
UNII(FDA)89BT58KELH

数据库记载的用途

  • Manufactured as an approximately equal mixture of two diasteromers.
  • Boceprevir, when used in combination with [DB00811], [DB00008], and [DB00022] is indicated for use in the treatment of chronic HCV genotype 1 infection in adults.
  • Boceprevir is an oral, direct acting hepatitis C virus (HCV) protease inhibitor that was used in combination with peginterferon and ribavirin in the treatment of chronic hepatitis C, genotype 1. Initially approved for use in 2012, it was withdrawn in 2015 because of the availability of more effective and better tolerated all oral regimens of direct acting antiviral agents. Boceprevir was not linked to instances of acute liver injury during therapy but, when combined with peginterferon and ribavirin, was associated
  • Breast Feeding; Lactation; Milk, Human; Antiviral Agents; Protease Inhibitors
  • Boceprevir is indicated for the treatment of chronic hepatitis C genotype 1 infection, in combination with peginterferon alfa and ribavirin, in adult patients (18 years and older) with compensated liver disease, including cirrhosis, who are previously untreated or who have failed previous interferon and ribavirin therapy. /Included in US product label/
  • Boceprevir must not be used as monotherapy and should only be used in combination with peginterferon alfa and ribavirin. /Included in US product label/

它在各数据库里的别名

Boceprevir; 394730-60-0; Victrelis; SCH 503034; EBP 520; SCH-503034; SCH503034; EBP-520; 89BT58KELH; CHEBI:68621; boceprevirum; RefChem:56897; J05AP03; MFCD22208555; SCH 50304; Boceprevir(>90%)

计算机算出的分子描述符

分子量519.7
XLogP33.1
氢键供体数4
氢键受体数5
可旋转键数10
精确质量519.34206955
单同位素质量519.34206955
拓扑极性表面积151
重原子数37
形式电荷0

数据库摘要

Boceprevir · CAS 394730-60-0 · C27H45N5O5. UNII 89BT58KELH.

数据来源:PubChem / Wikidata;与随货 COA 不一致时以 COA 为准。

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