Bictegravir

Name: Bictegravir
Brand: Jinan Shenghe Chemical Co., Ltd.

CAS 1611493-60-7C21H18F3N3O5MW 449.4

Bictegravir (CAS No. 1611493-60-7) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Pharmaceutical Intermediates & APIs. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Specifications

CAS Number1611493-60-7

Molecular FormulaC21H18F3N3O5

Molecular Weight449.4

Boiling Point682.5±55.0 °C at 760 mmHg

LogP2.7

Purity按批次COA提供(不公开发布)

Packaging按订单/批次确认(不公开发布)

ApplicationsPharmaceutical Intermediates & APIs

CategoryPharmaceutical Intermediates & APIs

Where it is used

Pharmaceutical Intermediates & APIs

Packaging & Supply

Packaging按订单/批次确认(不公开发布)

Purity按批次COA提供(不公开发布)

StorageSealed, cool and dry place

Lead TimeIn stock / per order

Documents & Support

COA provided with every batch; MSDS and technical documents available on request. Email us with product name and CAS number for a quote within one business day.

Frequently Asked Questions

What is the CAS number of Bictegravir?

The CAS number of Bictegravir is 1611493-60-7.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of Bictegravir?

Main applications include Pharmaceutical Intermediates & APIs.

How do I buy Bictegravir or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

Bictegravir · CAS 1611493-60-7 · C21H18F3N3O5. UNII 8GB79LOJ07. Boiling Point: 682.5±55.0 °C at 760 mmHg.

Identification

CAS Registry Number	1611493-60-7
PubChem CID	90311989
Molecular formula	C21H18F3N3O5
IUPAC name	(1S,11R,13R)-5-hydroxy-3,6-dioxo-N-[(2,4,6-trifluorophenyl)methyl]-12-oxa-2,9-diazatetracyclo[11.2.1.02,11.04,9]hexadeca-4,7-diene-7-carboxamide
UNII (FDA)	8GB79LOJ07

Computed Descriptors

Molecular Weight	449.4
XLogP3	2.7
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	3
Exact Mass	449.11985517
Monoisotopic Mass	449.11985517
Topological Polar Surface Area	99.2
Heavy Atom Count	32
Formal Charge	0

Physical & Chemical Properties

Boiling Point	682.5±55.0 °C at 760 mmHg

Physical description & handling notes

Bictegravir is an HIV-1 integrase strand transfer inhibitor (INSTI). Bictegravir (BIC) inhibits HIV-1 virus replication into the human genome. It can be taken once daily without additional dosing. Bictegravir (BIC) inhibits strand transfer of viral DNA into the host genome and thereby prevents HIV-1 replication.

Documented Uses

Bictegravir is a human immunodeficiency virus (HIV) integrase strand transfer inhibitor, the fourth in this class of agents that target the viral integrase. Bictegravir is used only in combination with other antiretroviral agents in the treatment of HIV infection and it has had limited use. Bictegravir is associated with a low rate of serum aminotransferase elevations during therapy, but has not been linked to instances of acute, clinically apparent liver injury.
Breast Feeding; Lactation; Milk, Human; Anti-Infective Agents; Antiviral Agents; Anti-HIV Agents; Anti-Retroviral Agents; HIV Integrase Inhibitors
Take at the same time every day.
Take separate from antacids. Take bictegravir at least 2 hours before or 6 hours after taking antacids containing aluminum or magnesium.
Take with food. When taking iron or calcium-containing products, bictegravir should be taken with food.
Bictegravir is rapidly absorbed within the body. Tmax= 2.0-4.0h

Synonyms

Bictegravir; 1611493-60-7; GS-9883; bictegravirum; GS-9883-01; 8GB79LOJ07; CHEBI:172943; DTXSID701027937; RefChem:568041; DTXCID901513504; Bictegravir [INN]; GS 9883; BICTEGRAVIR [USAN]; BICTEGRAVIR [WHO-DD]; D10909; Bictegravir (100 mg/mL in DMSO)

Frequently Asked Questions

What are the CAS number and molecular formula of Bictegravir?

CAS 1611493-60-7; molecular formula C21H18F3N3O5; molecular weight — g/mol.

What other names is Bictegravir known by?

Bictegravir, 1611493-60-7, GS-9883, bictegravirum, GS-9883-01, 8GB79LOJ07.

What are the key physical properties of Bictegravir?

Boiling Point: 682.5±55.0 °C at 760 mmHg.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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