苯并咪达韦

苯并咪达韦（CAS 176161-24-3）的公开数据库记录，列此仅供独立核对。

危险化学品分类与危害说明

这个物质在各数据库里的编号

数据库记载的用途

• Maribavir is indicated for the treatment of post-transplant cytomegalovirus (CMV) infection (following hematopoietic stem cell transplant or solid organ transplant) which is refractory to standard treatment with [ganciclovir], [valganciclovir], [cidofovir], or [foscarnet]. In the US, patients receiving the treatment should weigh more than 35 kg and be at least 12 years old. In Canada and Europe, maribavir is only approved in adults.
• Maribavir is an orally available, antiviral agent which inhibits the pUL97 kinase of cytomegalovirus (CMV) and is used to treat refractory forms of post-transplant CMV infection. Maribavir has been associated with low rates of mild-to-moderate serum aminotransferase elevations during therapy but has not been linked to cases of clinically apparent acute liver injury.
• Breast Feeding; Lactation; Milk, Human; Antiviral Agents
• Avoid St. John's Wort. Co-administration with St. John's wort decreases serum levels of maribavir and may decrease its therapeutic efficacy.
• Take with or without food. The co-administration of food with maribavir does not significantly affect its disposition.
• Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly.

它在各数据库里的别名

Maribavir; 176161-24-3; Benzimidavir; livtencity; 1263W94; Camvia; maribavirum; BW-1263W94; GW-257406X; (2S,3S,4R,5S)-2-[5,6-dichloro-2-(propan-2-ylamino)benzimidazol-1-yl]-5-(hydroxymethyl)oxolane-3,4-diol; GW-1263; PTB4X93HE1; BW 1263W94; 1263-W-94; DTXSID60170091; GW257406X

计算机算出的分子描述符

数据库摘要

BENZIMIDAVIR · CAS 176161-24-3 · C15H19Cl2N3O4. UNII PTB4X93HE1.

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。