Bromfenac

Description

Bromfenac · CAS 91714-94-2 · C15H12BrNO3. UNII 864P0921DW. Solubility: 1.26e-02 g/L; LogP: 3.4.

Identification

Computed Descriptors

Physical & Chemical Properties

Physical description & handling notes

• Solid
• Bromfenac ophthalmic solution is a sterile, topical, nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use.

Documented Uses

• For the treatment of postoperative inflammation in patients who have undergone cataract extraction.
• Breast Feeding; Lactation; Milk, Human; Analgesic Agents; Anti-inflammatory Agents, Nonsteroidal
• Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.
• Mechanisms of Action [MoA] - Cyclooxygenase Inhibitors
• Chemical Structure [CS] - Anti-Inflammatory Agents, Non-Steroidal
• Established Pharmacologic Class [EPC] - Nonsteroidal Anti-inflammatory Drug

Synonyms

Bromfenac; 91714-94-2; 2-(2-Amino-3-(4-bromobenzoyl)phenyl)acetic acid; 2-[2-amino-3-(4-bromobenzoyl)phenyl]acetic acid; Bromfenaco; Bromfenacum; 2-Amino-3-(4-bromobenzoyl)benzeneacetic acid; ISV-303; Benzeneacetic acid, 2-amino-3-(4-bromobenzoyl)-; DTXSID7040655; CHEBI:240107; 864P0921DW; [2-Amino-3-(4-bromo-benzoyl)-phenyl]-acetic acid; 2-{2-amino-3-[(4-bromophenyl)carbonyl]phenyl}acetic acid; (2-Amino-3-(4-bromo-benzoyl)-phenyl)-acetic acid; 2-(2-amino-3-((4-bromophenyl)carbonyl)phenyl)acetic acid

Frequently Asked Questions

What are the CAS number and molecular formula of Bromfenac?

CAS 91714-94-2; molecular formula C15H12BrNO3; molecular weight — g/mol.

What other names is Bromfenac known by?

Bromfenac, 91714-94-2, 2-(2-Amino-3-(4-bromobenzoyl)phenyl)acetic acid, 2-[2-amino-3-(4-bromobenzoyl)phenyl]acetic acid, Bromfenaco, Bromfenacum.

What are the key physical properties of Bromfenac?

Solubility: 1.26e-02 g/L; LogP: 3.4.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.