氯唑西林

Q: 氯唑西林 的 CAS 号是多少？

氯唑西林 的 CAS 登记号为 61-72-3。

Q: 氯唑西林 属于哪个分类？

所属分类：医药中间体及原料药。

CAS 61-72-3C19H18ClN3O5SMW 435.9

氯唑西林（CAS 61-72-3）：分子式 C19H18ClN3O5S、分子量 435.9；类别医药中间体及原料药。

产品描述

氯唑西林（CAS 61-72-3）是一种医药中间体及原料药原料。其分子式 C19H18ClN3O5S 由 19 个碳、18 个氢、1 个氯、3 个氮、5 个氧、1 个硫组成。分子量约为 435.9。公开物性数据显示其LogP 约 2.48。作为化工品采购代理与分销渠道，我们可在国内及跨境渠道为氯唑西林寻源比价，并安排小批量试样与批次采购；下单前提供完整 COA、质检报告与合规文件，验收以批次 COA 为准。

规格参数

CAS号61-72-3

分子式C19H18ClN3O5S

分子量435.9

LogP2.48

应用领域MEDICATION、Methods of Manufacturing: 6-Aminopenicillanic acid is acylated with 3-(o-chlorophenyl)-5- methyl-4-isoxazolecarboxylic acid and the resulting cloxacillin (acid) is purified by recrystallizations and converted to the sodium salt /Sodium Cloxacillin USP/、NOT RECOMMENDED IN US FOR USE IN FOOD PRODUCING ANIMALS、MORE RECENTLY INTRODUCED SEMISYNTHETIC DERIVATIVES OF PENICILLIN... CLOXACILLIN...SIMILAR IN ACTION TO PARENT COMPD BUT SOME ARE ALSO EFFECTIVE AGAINST...PENICILLINASE PRODUCING STAPHYLOCOCCI. /PENICILLINS/、SAFE TO ASSUME THAT AFTER...RECOMMENDED OR NON-RECOMMENDED USAGE FDA INSISTS TO ZERO TOLERANCE FOR DRUG IN EDIBLE TISSUES OF ANIMALS & POULTRY INCLUDING THEIR BY-PRODUCTS、MILK

类别医药中间体及原料药

用途与场景

登记用途：MEDICATION、Methods of Manufacturing: 6-Aminopenicillanic acid is acylated with 3-(o-chlorophenyl)-5- methyl-4-isoxazolecarboxylic acid and the resulting cloxacillin (acid) is purified by recrystallizations and converted to the sodium salt /Sodium Cloxacillin USP/、NOT RECOMMENDED IN US FOR USE IN FOOD PRODUCING ANIMALS、MORE RECENTLY INTRODUCED SEMISYNTHETIC DERIVATIVES OF PENICILLIN... CLOXACILLIN...SIMILAR IN ACTION TO PARENT COMPD BUT SOME ARE ALSO EFFECTIVE AGAINST...PENICILLINASE PRODUCING STAPHYLOCOCCI. /PENICILLINS/、SAFE TO ASSUME THAT AFTER...RECOMMENDED OR NON-RECOMMENDED USAGE FDA INSISTS TO ZERO TOLERANCE FOR DRUG IN EDIBLE TISSUES OF ANIMALS & POULTRY INCLUDING THEIR BY-PRODUCTS、MILK。

采购档案

这个产品是什么

氯唑西林是一种医药中间体或原料药类化合物，登记 CAS 号为 61-72-3，分子式 C19H18ClN3O5S（分子量 435.9），归属于医药中间体及原料药大类化工原料。

识别信息

登记 CAS 号：61-72-3

其分子式 C19H18ClN3O5S 由 19 个碳、18 个氢、1 个氯、3 个氮、5 个氧、1 个硫组成。

别名/同义词：氯唑西林 · cloxacillin

所属分类：医药中间体及原料药

常见问题

氯唑西林的 CAS 号是多少？

氯唑西林的 CAS 登记号为 61-72-3。

氯唑西林的分子式与分子量是多少？

分子式 C19H18ClN3O5S，分子量 435.9。

氯唑西林还有哪些别名？

别名/同义词：氯唑西林、cloxacillin。

氯唑西林的登记用途是什么？

氯唑西林属于哪个分类？

所属分类：医药中间体及原料药。

如何在 591daili.cn 采购氯唑西林？

请在联系页面提交产品名称、CAS 号与数量，我们作为采购代理在国内及跨境渠道为您寻源比价，安排试样与批次采购，下单前提供 COA 与合规文件。

包装与单证

包装按订单确认，从实验室小包装到吨袋大货，随订单安排而非在页面上写死。每批随货附 COA 分析证书，可另提供 MSDS；若终端用途带有法规限度（食品接触、药品或化妆品），请在询价时说明执行标准，等级按该标准确定。

PubChem 公开数据

氯唑西林（CAS 61-72-3）的公开数据库记录，列此仅供独立核对。

危险化学品分类与危害说明

Reported hazard statements	H315 (85.4%), H317 (91.7%), H319 (85.4%), H334 (97.9%), H335 (85.4%)

H315 (85.4%): Causes skin irritation [Warning Skin corrosion/irritation]

H317 (91.7%): May cause an allergic skin reaction [Warning Sensitization, Skin]

物理形态与操作说明

Solid
WHITE, CRYSTALLINE POWDER; SOL IN ALCOHOL; SLIGHTLY SOL IN ACETONE, CHLOROFORM; AQ SOLN IS ALKALINE; DECOMP BETWEEN 170 °C & 173 °C; ODORLESS; BITTER TASTE /MONOHYDRATE/
CLOXACILLIN IS RELATIVELY STABLE IN GASTRIC ACID; STABLE IN LIGHT; SLIGHTLY HYGROSCOPIC. /MONOHYDRATE/
AQ SOLN FOR INJECTIONS ARE STABLE FOR AT LEAST 3 DAYS IF REFRIGERATED.
Penicillinase-resistant penicillins are generally stable in the dry state @ room temp for several yr; however, the drugs are stable only for short periods of time in soln unless frozen. Stability of the drugs is pH and temp dependent. Methicillin, nafcillin, and oxacillin are generally stable @ pH 5-8. /Penicillinase-resistant penicillins/
189.3 Å² [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

公开数据库收录的理化数据

溶解度	5.32e-02 g/L
LogP	2.48
LogP	LogP = 2.44
LogP	2.86
Dissociation Constants	2.78
Collision Cross Section	200.94 Å² [M-H]-

这个物质在各数据库里的编号

CAS Registry Number	61-72-3
PubChem CID	6098
分子式	C19H18ClN3O5S
IUPAC 名称	(2S,5R,6R)-6-[[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
UNII（FDA）	O6X5QGC2VB

数据库记载的用途

6-Aminopenicillanic acid is acylated with 3-(o-chlorophenyl)-5- methyl-4-isoxazolecarboxylic acid and the resulting cloxacillin (acid) is purified by recrystallizations and converted to the sodium salt /Sodium Cloxacillin USP/
NOT RECOMMENDED IN US FOR USE IN FOOD PRODUCING ANIMALS.
MORE RECENTLY INTRODUCED SEMISYNTHETIC DERIVATIVES OF PENICILLIN... CLOXACILLIN...SIMILAR IN ACTION TO PARENT COMPD BUT SOME ARE ALSO EFFECTIVE AGAINST...PENICILLINASE PRODUCING STAPHYLOCOCCI. /PENICILLINS/
...SAFE TO ASSUME THAT AFTER...RECOMMENDED OR NON-RECOMMENDED USAGE FDA INSISTS TO ZERO TOLERANCE FOR DRUG IN EDIBLE TISSUES OF ANIMALS & POULTRY INCLUDING THEIR BY-PRODUCTS, MILK, OR EGGS DESTINED FOR HUMAN USE...CURRENTLY PERMITTING 0.05 PPM FOR ITS NEGLIGIBLE RESIDUE IN UNCOOKED EDIBLE TISSUES OF CATTLE. /PENICILLINS/
PROPERTIES & PHARMACOLOGY: NAYLOR ET AL, NATURE 195, 1264 (1962).
Cloxacillin is indicated for the treatment of beta-hemolytic streptococcal, pneumococcal, and staphylococcal infections (including beta-lactamase producing organisms).

它在各数据库里的别名

cloxacillin; 61-72-3; Cloxacilline; Cloxacillinum; Cloxacilina; Methocillin S; Syntarpen; Clossacillina; Chloroxacillin; O6X5QGC2VB; (3-(o-Chlorophenyl)-5-methyl-4-isoxazolyl)penicillin; CHEBI:49566; 6-(3-(o-Chlorophenyl)-5-methyl-4-isoxazolecarboxamido)penicillanic acid; cloxacillina; Cloxacillin, Sodium; Sodium, Cloxacillin

计算机算出的分子描述符

分子量	435.9
XLogP3	2.4
氢键供体数	2
氢键受体数	7
可旋转键数	4
精确质量	435.0655696
单同位素质量	435.0655696
拓扑极性表面积	138
重原子数	29
形式电荷	0

数据库摘要

cloxacillin · CAS 61-72-3 · C19H18ClN3O5S. UNII O6X5QGC2VB. 溶解度: 5.32e-02 g/L; LogP: 2.48; LogP: LogP = 2.44.

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。

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