卡洛芬

卡洛芬（CAS 53716-49-7）的公开数据库记录，列此仅供独立核对。

危险化学品分类与危害说明

法规与备案状态

物理形态与操作说明

• Solid
• Practically insoluble at 25 °C
• >41.1 [ug/mL] (The mean of the results at pH 7.4)
• 156.1 Ų [M+H]+ [CCS Type: TW]
• 161.46 Ų [M+K]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• Carprofen is a non-steroidal anti-inflammatory drug (NSAID) of the propionic acid class that includes ibuprofen, naproxen, and ketoprofen. It is no longer used in the clinical setting, but is approved for use in dogs. Carprofen is non-narcotic and has characteristic analgesic and antipyretic activity approximately equipotent to indomethacin in animal models.

公开数据库收录的理化数据

这个物质在各数据库里的编号

数据库记载的用途

• Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients
• Pharmaceuticals -> Animal Drugs -> Approved in Taiwan
• For use as a pain reliever in the treatment of joint pain and post-surgical pain.
• Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.
• Drugs that are pharmacologically inactive but when exposed to ultraviolet radiation or sunlight are converted to their active metabolite to produce a beneficial reaction affecting the diseased tissue. These compounds can be administered topically or systemically and have been used therapeutically to treat psoriasis and various types of neoplasms.
• QM01 - Antiinflammatory and antirheumatic products

它在各数据库里的别名

carprofen; 53716-49-7; 2-(6-Chloro-9H-carbazol-2-yl)propanoic acid; Rimadyl; Carprofeno; 6-Chloro-alpha-methyl-9H-carbazole-2-acetic acid; Carprofene; Carprofenum; Carprodyl; 6-Chloro-alpha-methylcarbazole-2-acetic acid; Ro 20-5720/000; DTXSID1045871; Ro-20-5720/000; Rimadyl Caplets; (+-)-6-Chloro-alpha-methylcarbazole-2-acetic acid; Carprofen for veterinary use

计算机算出的分子描述符

数据库摘要

6-chloro-α-methyl-9H-carbazole-2-acetic acid · CAS 53716-49-7 · C15H12ClNO2. UNII FFL0D546HO. 熔点: 195-199; 熔点: 197.5 °C; 溶解度: 3.79e-03 g/L.

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。