盐酸西那卡塞

Description

Cinacalcet hydrochloride · CAS 364782-34-3 · C22H23ClF3N. UNII 1K860WSG25.

Identification

CAS Registry Number	364782-34-3
PubChem CID	156418
Molecular formula	C22H23ClF3N
IUPAC name	N-[(1R)-1-naphthalen-1-ylethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine;hydrochloride
UNII (FDA)	1K860WSG25

Computed Descriptors

Molecular Weight	393.9
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	6
Exact Mass	393.1471119
Monoisotopic Mass	393.1471119
Topological Polar Surface Area	12
Heavy Atom Count	27
Formal Charge	0
Complexity	422

Regulatory Status

GHS notification summary	9.1% (1 / 11)

GHS Hazard Classification

GHS notification summary	9.1% (1 / 11)
Reported hazard statements	H302 (45.5%), H317 (36.4%), H318 (45.5%), H319 (36.4%), H373 (54.5%), H400 (36.4%), H410 (45.5%)

Documented Uses

• Breast Feeding; Lactation; Milk, Human; Calcium-Regulating Hormones and Agents; Calcimimetic Agents
• Hormones and molecules with calcium-regulating hormone-like actions that modulate OSTEOLYSIS and other extra-skeletal activities to maintain calcium homeostasis.
• Small organic molecules that act as allosteric activators of the calcium sensing receptor (CaSR) in the PARATHYROID GLANDS and other tissues. They lower the threshold for CaSR activation by extracellular calcium ions and diminish PARATHYROID HORMONE (PTH) release from parathyroid cells.
• Calcium-sensing Receptor Agonist [EPC]; Increased Calcium-sensing Receptor Sensitivity [MoA]

Synonyms

Cinacalcet hydrochloride; 364782-34-3; Cinacalcet HCl; Mimpara; AMG073 HCl; DTXSID3046792; AMG-073 HCL; AMG073 hydrochloride; 1K860WSG25; DTXCID1026792; CHEBI:48391; 1-Naphthalenemethanamine, a-methyl-N-(3-(3-(trifluoromethyl)phenyl)propyl)-,(aR)-, Hydrochloride; RefChem:57402; 620-490-5; Sensipar; (R)-N-(1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine hydrochloride

Frequently Asked Questions

What are the CAS number and molecular formula of Cinacalcet hydrochloride?

CAS 364782-34-3; molecular formula C22H23ClF3N; molecular weight — g/mol.

What other names is Cinacalcet hydrochloride known by?

Cinacalcet hydrochloride, 364782-34-3, Cinacalcet HCl, Mimpara, AMG073 HCl, DTXSID3046792.

Is Cinacalcet hydrochloride classified as hazardous?

9.1% of GHS notifications report no hazard classification (1 of 11).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.